Publications by authors named "Elvin D de Araujo"

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The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease.
Lindsay Kosack, Bettina Wingelhofer, Alexandra Popa, Anna Orlova, Benedikt Agerer, Bojan Vilagos, Peter Majek, Katja Parapatics, Alexander Lercher, Anna Ringler

Cancer Cell· January 2019

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Thyroid hormone receptor beta signaling is a targetable driver of prostate cancer growth.
Aleksandra Fesiuk, Daniel Pölöske, Elvin D de Araujo, Geordon A Frere, Timothy B Wright

Mol Cancer· October 2025

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Improved Pharmacokinetic Profiles of HDAC6 Inhibitors via Cap Group Modifications.
Olasunkanmi O Olaoye, Fettah Erdogan, Maria Gracia-Hernandez, Harsimran Kaur Garcha, Abootaleb Sedighi, Elvin D de Araujo

J Med Chem· September 2025

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Allosteric Covalent Inhibitors of the STAT3 Transcription Factor from Virtual Screening.
Tibor Viktor Szalai, Vincenzo di Lorenzo, Nikolett Péczka, Levente M Mihalovits, László Petri, Elvin D de Araujo

ACS Med Chem Lett· June 2025

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Monoselective Histone Deacetylase 6 PROTAC Degrader Shows Tractability.
Harsimran K Garcha, Olasunkanmi O Olaoye, Abootaleb Sedighi, Daniel Pölöske, Pearla Hariri, Elvin D de Araujo

J Med Chem· March 2025

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Microwave-assisted synthesis of pomalidomide building blocks for rapid PROTAC and molecular glue development.
Diaaeldin I Abdallah, Johan Israelian, Lina S Hasan, Naman H Patel, Jeffrey W Keillor, Elvin D de Araujo

Chem Commun (Camb)· March 2025

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The structural influence of the oncogenic driver mutation N642H in the STAT5B SH2 domain.
Liam Haas-Neill, Deniz Meneksedag-Erol, Ayesha Chaudhry, Masha Novoselova, Qirat F Ashraf, Elvin D de Araujo

Protein Sci· January 2025

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Dual specific STAT3/5 degraders effectively block acute myeloid leukemia and natural killer/T cell lymphoma.
Daniel Pölöske, Helena Sorger, Anna Schönbichler, Elvin D de Araujo, Heidi A Neubauer

Hemasphere· December 2024

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De novo GTP synthesis is a metabolic vulnerability for the interception of brain metastases.
Agata M Kieliszek, Daniel Mobilio, Blessing I Bassey-Archibong, Jarrod W Johnson, Mathew L Piotrowski, Elvin D de Araujo

Cell Rep Med· October 2024

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Mapping protein binding sites by photoreactive fragment pharmacophores.
Péter Ábrányi-Balogh, Dávid Bajusz, Zoltán Orgován, Aaron B Keeley, László Petri, Elvin D de Araujo

Commun Chem· July 2024

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Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia.
Tobias Suske, Helena Sorger, Gabriele Manhart, Frank Ruge, Nicole Prutsch, Elvin Dominic de Araujo

J Clin Invest· April 2024

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Discovery of YSR734: A Covalent HDAC Inhibitor with Cellular Activity in Acute Myeloid Leukemia and Duchenne Muscular Dystrophy.
Yasir S Raouf, Abootaleb Sedighi, Mulu Geletu, Geordon A Frere, Rebecca G Allan, Elvin D de Araujo

J Med Chem· December 2023

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Inhibitor Library Screening of SH2 Domains Through Denaturation-Based Assays.
Elvin D de Araujo, Anna Orlova, Qirat F Ashraf, Richard Moriggl, Patrick T Gunning

Methods Mol Biol· September 2023

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Medicinal chemistry advances in targeting class I histone deacetylases.
Diaaeldin I Abdallah, Elvin D de Araujo, Naman H Patel, Lina S Hasan, Richard Moriggl

Explor Target Antitumor Ther· August 2023

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SH2db, an information system for the SH2 domain.
Dávid Bajusz, Gáspár Pándy-Szekeres, Ágnes Takács, Elvin D de Araujo, György M Keserű

Nucleic Acids Res· July 2023

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Histone deacetylase inhibitors as a potential new treatment for psoriatic disease and other inflammatory conditions.
Jehan Mohammad Nazri, Katerina Oikonomopoulou, Elvin D de Araujo, Dziyana Kraskouskaya, Patrick T Gunning

Crit Rev Clin Lab Sci· June 2023

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Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T-cell lymphoma.
Helena Sorger, Saptaswa Dey, Pablo Augusto Vieyra-Garcia, Daniel Pölöske, Andrea R Teufelberger, Elvin D de Araujo

EMBO Mol Med· December 2022

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Evaluation of Small-Molecule HDAC Inhibitors Through In Vitro and In Cellulo Approaches.
Nabanita Nawar, Harsimran Kaur Garcha, Abootaleb Sedighi, Elvin D de Araujo, Patrick T Gunning

Methods Mol Biol· October 2022

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Fluorescence Polarization-Based Competition Assays to Evaluate Histone Deacetylase 6 Inhibitors.
Qirat F Ashraf, Erica J Quilates, Olasunkanmi O Olaoye, Elvin D de Araujo, Patrick T Gunning

Methods Mol Biol· October 2022

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High Efficacy and Drug Synergy of HDAC6-Selective Inhibitor NN-429 in Natural Killer (NK)/T-Cell Lymphoma.
Harsimran Kaur Garcha, Nabanita Nawar, Helena Sorger, Fettah Erdogan, Myint Myat Khine Aung, Elvin D de Araujo

Pharmaceuticals (Basel)· October 2022

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Phenotypic Screening of Histone Deacetylase (HDAC) Inhibitors against Schistosoma mansoni.
Muhammad Murtaza Hassan, Abootaleb Sedighi, Olasunkanmi O Olaoye, Cécile Häberli, Annika Merz, Elvin D de Araujo

ChemMedChem· September 2022

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Emerging mechanisms of targeted protein degradation by molecular glues.
Geordon A Frere, Elvin D de Araujo, Patrick T Gunning

Methods Cell Biol· May 2022

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JAK-STAT core cancer pathway: An integrative cancer interactome analysis.
Fettah Erdogan, Tudor Bogdan Radu, Anna Orlova, Abdul Khawazak Qadree, Elvin Dominic de Araujo

J Cell Mol Med· April 2022

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Structural and mutational analysis of member-specific STAT functions.
Fettah Erdogan, Abdul K Qadree, Tudor B Radu, Anna Orlova, Elvin D de Araujo

Biochim Biophys Acta Gen Subj· March 2022

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Discovery of HDAC6-Selective Inhibitor NN-390 with Efficacy in Group 3 Medulloblastoma.
Nabanita Nawar, Shazreh Bukhari, Ashley A Adile, Yujin Suk, Pimyupa Manaswiyoungkul, Elvin D de Araujo

J Med Chem· February 2022

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Efficacy and Synergy of Small Molecule Inhibitors Targeting -ITD Acute Myeloid Leukemia.
Javier Bregante, Anna Schönbichler, Daniel Pölöske, Lina Degenfeld-Schonburg, Garazi Monzó Contreras, Elvin D de Araujo

Cancers (Basel)· December 2021

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