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Cancer Cell January 2019 PMID 30645971

The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease.

Lindsay Kosack, Bettina Wingelhofer, Alexandra Popa, Anna Orlova, Benedikt Agerer, Bojan Vilagos, Peter Majek, Katja Parapatics, Alexander Lercher, Anna Ringler, Johanna Klughammer, Mark Smyth, Kseniya Khamina, Hatoon Baazim, Elvin D de Araujo

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Mentions

44
Peak: 9 in Apr 2019
across 5 sources since Jan 2019

Extended reach

365,438
potential audience

Total likes

106

Video views

5,670

Mentions per month

Jan 2019 – Apr 2025

Where it's discussed

  • X / Twitter19 posts
  • News14 articles
  • Facebook5 posts
  • Blogs4 articles
  • YouTube2 videos

AI synopsis

What people are saying

Discussions frequently highlight the significance of the ERBB-STAT3 pathway in driving the disease, with tone emphasizing the potential for new treatments and conservation solutions, such as phrases like 'interesting story' and references to research publications, indicating a keen interest and acknowledgment of the research's importance.

AgreementModerate agreement

Most discussions acknowledge the importance of the research, referencing the ERBB-STAT3 pathway as a key driver of the disease.

InterestHigh interest

The posting volume and phrases like 'interesting story' reflect high interest among the participants.

EngagementModerate engagement

The mentions of research details and referencing specific papers suggest moderate effort to understand and share insights.

ImpactModerate impact

The recognition that targeting this pathway could have conservation and therapeutic implications indicates perceived high impact.

Abstract in brief

  • The study explores the molecular mechanisms behind the transmissible Tasmanian devil facial tumor disease (DFTD), highlighting the role of the ERBB-STAT3 pathway.
  • Researchers found that inhibiting ERBB or STAT3 can stop tumor growth, restore immune system markers, and may offer a dual therapeutic approach to protect Tasmanian devils.
  • The findings suggest that targeting this signaling axis could be key to understanding and fighting transmissible cancers, with implications for both conservation and cancer biology.
Read the full abstract

Top posts

Most liked on X and Bluesky
Cancer Cell
@Cancer_Cell · X

The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease https://t.co/bbsCCZDM2i by Kosack, Bergthaler @oeaw & co, reference 11. https://t.co/kQM0dPaQb1

Apr 3, 2019 · 14 likes · 2 shares · 72,276 followers View post →
Cancer Cell
@Cancer_Cell · X

The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease https://t.co/bbsCCZDM2i by Kosack, Bergthaler @oeaw & co, reference 11. https://t.co/RRne4EiLcb

Apr 3, 2019 · 14 likes · 5 shares · 72,276 followers View post →
ふぁっふぉい
@sugikota · X

タスマニアデビルの悪性神経鞘腫、Devil Facial Tumor Disease (DFTD)の参考文献: (新しい総説がないのでこの原著から孫引きする方がよい) The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease https://t.co/mDICIRKhj3

Aug 1, 2024 · 8 likes · 11,487 followers View post →
Oncologiavet
@oncologiavet · X

The ERBB-STAT3 axis drives Tasmanian devil facial tumor disease. https://t.co/wXwds3D22A

Jan 18, 2019 · 4 likes · 1 share · 4,555 followers View post →
Gunning Group
@GunningLabUofT · X

You can read more about this interesting story in the @Cancer_Cell paper we published together with Profs. Moriggl and Bergthaler last year: The ERBB-#STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease. https://t.co/x5sLJuAsmD

Jun 22, 2020 · 2 likes · 1 share · 2,451 followers View post →
まきまき
@qwertymcn · X

The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease https://t.co/3qXVEEBNBD xenograft疾患ってイヌの可移植性性器肉腫以外にもあるんだっていう驚き

Jan 17, 2020 · 2 likes · 856 followers View post →

All mentions

ふぁっふぉい
@sugikota · X

タスマニアデビルの悪性神経鞘腫、Devil Facial Tumor Disease (DFTD)の参考文献: (新しい総説がないのでこの原著から孫引きする方がよい) The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease https://t.co/mDICIRKhj3

Aug 1, 2024 · 8 likes · 11,487 followers View post →
Elvin de Araujo
@e_dearaujo · X

RT @GunningLabUofT: You can read more about this interesting story in the @Cancer_Cell paper we published together with Profs. Moriggl and…

Jun 25, 2020 · 1 share · 96 followers View post →
Gunning Group
@GunningLabUofT · X

You can read more about this interesting story in the @Cancer_Cell paper we published together with Profs. Moriggl and Bergthaler last year: The ERBB-#STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease. https://t.co/x5sLJuAsmD

Jun 22, 2020 · 2 likes · 1 share · 2,451 followers View post →
まきまき
@qwertymcn · X

The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease https://t.co/3qXVEEBNBD xenograft疾患ってイヌの可移植性性器肉腫以外にもあるんだっていう驚き

Jan 17, 2020 · 2 likes · 856 followers View post →
CeMM Papers
@CeMM_papers · X

The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease. https://t.co/ixQoKe2i73

Oct 19, 2019 · 541 followers View post →
jesusanampa
@jesusanampa · X

RT @Cancer_Cell: The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease https://t.co/bbsCCZDM2i by Kosack, Bergthaler @oeaw & co,…

Apr 3, 2019 · 2 shares · 8,169 followers View post →
Lennis O
@lennisque · X

RT @Cancer_Cell: The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease https://t.co/bbsCCZDM2i by Kosack, Bergthaler @oeaw & co,…

Apr 3, 2019 · 5 shares · 54 followers View post →
filippo masini
@filimasini · X

RT @oncologiavet: The ERBB-STAT3 axis drives Tasmanian devil facial tumor disease. https://t.co/wXwds3D22A

Apr 3, 2019 · 1 share · 770 followers View post →
Katsuaki Maehara
@KatsuakiMaehara · X

RT @Cancer_Cell: The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease https://t.co/bbsCCZDM2i by Kosack, Bergthaler @oeaw & co,…

Apr 3, 2019 · 5 shares · 2,941 followers View post →
Jean-Médard ZOLA
@jmzola2017 · X

RT @Cancer_Cell: The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease https://t.co/bbsCCZDM2i by Kosack, Bergthaler @oeaw & co,…

Apr 3, 2019 · 2 shares · 240 followers View post →
Jean-Médard ZOLA
@jmzola2017 · X

RT @Cancer_Cell: The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease https://t.co/bbsCCZDM2i by Kosack, Bergthaler @oeaw & co,…

Apr 3, 2019 · 5 shares · 240 followers View post →
ゐぬめゑ
@inumay · X

RT @Cancer_Cell: The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease https://t.co/bbsCCZDM2i by Kosack, Bergthaler @oeaw & co,…

Apr 3, 2019 · 5 shares · 262 followers View post →
Cancer Cell
@Cancer_Cell · X

The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease https://t.co/bbsCCZDM2i by Kosack, Bergthaler @oeaw & co, reference 11. https://t.co/RRne4EiLcb

Apr 3, 2019 · 14 likes · 5 shares · 72,276 followers View post →
Cancer Cell
@Cancer_Cell · X

The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease https://t.co/bbsCCZDM2i by Kosack, Bergthaler @oeaw & co, reference 11. https://t.co/kQM0dPaQb1

Apr 3, 2019 · 14 likes · 2 shares · 72,276 followers View post →
Collectibulldogs
@collectibulldog · X

RT @oncologiavet: The ERBB-STAT3 axis drives Tasmanian devil facial tumor disease. https://t.co/wXwds3D22A

Jan 20, 2019 · 1 share · 181,019 followers View post →
filippo masini
@filimasini · X

RT @oncologiavet: The ERBB-STAT3 axis drives Tasmanian devil facial tumor disease. https://t.co/wXwds3D22A

Jan 20, 2019 · 1 share · 770 followers View post →
Oncologiavet
@oncologiavet · X

The ERBB-STAT3 axis drives Tasmanian devil facial tumor disease. https://t.co/wXwds3D22A

Jan 18, 2019 · 4 likes · 1 share · 4,555 followers View post →
CeMM Papers
@CeMM_papers · X

The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease. https://t.co/JyeMLKWlOd

Jan 16, 2019 · 1 like · 541 followers View post →
marsupialpapers
@marsup_papers · X

The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease. https://t.co/OMwcvPi3Tv https://t.co/QwUbnIzALB

Jan 16, 2019 · 1 like · 150 followers View post →