Publications by authors named "Emi Lutz"

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PD-1 blockade during T cell priming enhances long-term protection against metastatic tumors by epigenetically tuning T cell exhaustion.
Teresa Dinter, Sebastian Mackowiak, Zachary J Rogers, Vidit Bhandarkar, Molly Y Carney, Emi Lutz

bioRxiv· November 2025

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CD8 T cell priming that is required for curative intratumorally anchored anti-4-1BB immunotherapy is constrained by Tregs.
Joseph R Palmeri, Brianna M Lax, Joshua M Peters, Lauren Duhamel, Jordan A Stinson, Emi A Lutz

Nat Commun· March 2024

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Enhanced Vaccine Immunogenicity Enabled by Targeted Cytosolic Delivery of Tumor Antigens into Dendritic Cells.
Nicholas L Truex, Aurélie Rondon, Simon L Rössler, Cameron C Hanna, Yehlin Cho, Emi A Lutz

ACS Cent Sci· September 2023

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Both intratumoral regulatory T cell depletion and CTLA-4 antagonism are required for maximum efficacy of anti-CTLA-4 antibodies.
Brianna M Lax, Joseph R Palmeri, Emi A Lutz, Allison Sheen, Jordan A Stinson

Proc Natl Acad Sci U S A· August 2023

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Tregs constrain CD8 T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy.
Joseph R Palmeri, Brianna M Lax, Joshua M Peters, Lauren Duhamel, Jordan A Stinson, Emi A Lutz

bioRxiv· February 2023

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Intratumoral nanobody-IL-2 fusions that bind the tumor extracellular matrix suppress solid tumor growth in mice.
Emi A Lutz, Noor Jailkhani, Noor Momin, Ying Huang, Allison Sheen

PNAS Nexus· November 2022

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Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies.
Emi A Lutz, Yash Agarwal, Noor Momin, Sarah C Cowles, Joseph R Palmeri

Proc Natl Acad Sci U S A· September 2022

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An affinity threshold for maximum efficacy in anti-PD-1 immunotherapy.
Sarah C Cowles, Allison Sheen, Luciano Santollani, Emi A Lutz, Brianna M Lax

MAbs· August 2022

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Type I interferon activates MHC class I-dressed CD11b conventional dendritic cells to promote protective anti-tumor CD8 T cell immunity.
Ellen Duong, Tim B Fessenden, Emi Lutz, Teresa Dinter, Leon Yim

Immunity· February 2022

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Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity.
Yash Agarwal, Lauren E Milling, Jason Y H Chang, Luciano Santollani, Allison Sheen, Emi A Lutz

Nat Biomed Eng· February 2022

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Maximizing response to intratumoral immunotherapy in mice by tuning local retention.
Noor Momin, Joseph R Palmeri, Emi A Lutz, Noor Jailkhani, Howard Mak

Nat Commun· January 2022

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Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy.
Noor Momin, Naveen K Mehta, Nitasha R Bennett, Leyuan Ma, Joseph R Palmeri, Emi A Lutz

Sci Transl Med· June 2019

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Efficient Identification of Murine M2 Macrophage Peptide Targeting Ligands by Phage Display and Next-Generation Sequencing.
Gary W Liu, Brynn R Livesay, Nataly A Kacherovsky, Maryelise Cieslewicz, Emi Lutz

Bioconjug Chem· August 2015

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