Publications by authors named "Emily Button"

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Exidavnemab binds to aggregated α-synuclein in human brains affected by α-synucleinopathies.
Olof Zachrisson, Malin Johannesson, Linda Söderberg, Fredrik Eriksson, Dan Sunnemark, Emily B Button

Neurotherapeutics· November 2025

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Lecanemab demonstrates highly selective binding to Aβ protofibrils isolated from Alzheimer's disease brains.
Malin Johannesson, Linda Söderberg, Olof Zachrisson, Nicolas Fritz, Helen Kylefjord, Emily Button

Mol Cell Neurosci· September 2024

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Amyloid-beta antibody binding to cerebral amyloid angiopathy fibrils and risk for amyloid-related imaging abnormalities.
Linda Söderberg, Malin Johannesson, Eleni Gkanatsiou, Patrik Nygren, Nicolas Fritz, Emily Button

Sci Rep· May 2024

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Characterization of functionally deficient SIM2 variants found in patients with neurological phenotypes.
Emily L Button, Joseph J Rossi, Daniel P McDougal, John B Bruning, Daniel J Peet

Biochem J· July 2022

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Toward three-dimensional models to study neurovascular unit functions in health and disease.
Tara M Caffrey, Emily B Button, Jerome Robert

Neural Regen Res· November 2021

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Development of a novel, sensitive translational immunoassay to detect plasma glial fibrillary acidic protein (GFAP) after murine traumatic brain injury.
Emily B Button, Wai Hang Cheng, Carlos Barron, Honor Cheung, Asma Bashir

Alzheimers Res Ther· March 2021

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An in vitro bioengineered model of the human arterial neurovascular unit to study neurodegenerative diseases.
Jerome Robert, Nicholas L Weilinger, Li-Ping Cao, Stefano Cataldi, Emily B Button

Mol Neurodegener· November 2020

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Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E.
Jerome Robert, Emily B Button, Emma M Martin, Luke McAlary, Zoe Gidden

Mol Neurodegener· March 2020

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Increased severity of the CHIMERA model induces acute vascular injury, sub-acute deficits in memory recall, and chronic white matter gliosis.
Asma Bashir, Zelalem A Abebe, Kurt A McInnes, Emily B Button, Igor Tatarnikov

Exp Neurol· February 2020

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HDL from an Alzheimer's disease perspective.
Emily B Button, Jérôme Robert, Tara M Caffrey, Jianjia Fan, Wenchen Zhao

Curr Opin Lipidol· June 2019

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ApoA-I deficiency increases cortical amyloid deposition, cerebral amyloid angiopathy, cortical and hippocampal astrogliosis, and amyloid-associated astrocyte reactivity in APP/PS1 mice.
Emily B Button, Guilaine K Boyce, Anna Wilkinson, Sophie Stukas, Arooj Hayat

Alzheimers Res Ther· May 2019

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CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP/PS1 mice.
Wai Hang Cheng, Kris M Martens, Asma Bashir, Honor Cheung, Sophie Stukas, Emily B Button

Alzheimers Res Ther· January 2019

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Vasoprotective Functions of High-Density Lipoproteins Relevant to Alzheimer's Disease Are Partially Conserved in Apolipoprotein B-Depleted Plasma.
Emily B Button, Megan Gilmour, Harleen K Cheema, Emma M Martin, Andrew Agbay

Int J Mol Sci· January 2019

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Age at injury and genotype modify acute inflammatory and neurofilament-light responses to mild CHIMERA traumatic brain injury in wild-type and APP/PS1 mice.
Wai Hang Cheng, Sophie Stukas, Kris M Martens, Dhananjay R Namjoshi, Emily B Button

Exp Neurol· March 2018

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Clearance of beta-amyloid is facilitated by apolipoprotein E and circulating high-density lipoproteins in bioengineered human vessels.
Jerome Robert, Emily B Button, Brian Yuen, Megan Gilmour, Kevin Kang

Elife· October 2017

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High-density lipoproteins suppress Aβ-induced PBMC adhesion to human endothelial cells in bioengineered vessels and in monoculture.
Jérôme Robert, Emily B Button, Sophie Stukas, Guilaine K Boyce, Ebrima Gibbs

Mol Neurodegener· August 2017

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HIF has Biff - Crosstalk between HIF1a and the family of bHLH/PAS proteins.
Emily L Button, David C Bersten, Murray L Whitelaw

Exp Cell Res· July 2017

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The pleiotropic vasoprotective functions of high density lipoproteins (HDL).
Guilaine Boyce, Emily Button, Sonja Soo, Cheryl Wellington

J Biomed Res· May 2017

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Reconstituted high-density lipoproteins acutely reduce soluble brain Aβ levels in symptomatic APP/PS1 mice.
Jérôme Robert, Sophie Stukas, Emily Button, Wai Hang Cheng, Michael Lee

Biochim Biophys Acta· May 2016

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The ad-libitum alcohol 'taste test': secondary analyses of potential confounds and construct validity.
Andrew Jones, Emily Button, Abigail K Rose, Eric Robinson, Paul Christiansen

Psychopharmacology (Berl)· March 2016

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Fasting upregulates adipose triglyceride lipase and hormone-sensitive lipase levels and phosphorylation in mouse kidney.
Phillip M Marvyn, Ryan M Bradley, Emily B Button, Emily B Mardian, Robin E Duncan

Biochem Cell Biol· June 2015

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Microglial cell activation increases saturated and decreases monounsaturated fatty acid content, but both lipid species are proinflammatory.
Emily B Button, Andrew S Mitchell, Marcia M Domingos, Jessica H-J Chung, Ryan M Bradley

Lipids· April 2014

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