Publications by authors named "Emily F Ruff"

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Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states.
Eric W Lake, Joseph M Muretta, Andrew R Thompson, Damien M Rasmussen, Abir Majumdar, Emily F Ruff

Proc Natl Acad Sci U S A· December 2018

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A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation.
Emily F Ruff, Joseph M Muretta, Andrew R Thompson, Eric W Lake, Soreen Cyphers

Elife· February 2018

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A water-mediated allosteric network governs activation of Aurora kinase A.
Soreen Cyphers, Emily F Ruff, Julie M Behr, John D Chodera, Nicholas M Levinson

Nat Chem Biol· April 2017

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Mechanism of transcription initiation and promoter escape by . RNA polymerase.
Kate L Henderson, Lindsey C Felth, Cristen M Molzahn, Irina Shkel, Si Wang, Emily F Ruff

Proc Natl Acad Sci U S A· April 2017

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Using solutes and kinetics to probe large conformational changes in the steps of transcription initiation.
Emily F Ruff, Wayne S Kontur, M Thomas Record

Methods Mol Biol· October 2015

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E. coli RNA Polymerase Determinants of Open Complex Lifetime and Structure.
Emily F Ruff, Amanda C Drennan, Michael W Capp, Mikaela A Poulos, Irina Artsimovitch

J Mol Biol· July 2015

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Initial events in bacterial transcription initiation.
Emily F Ruff, M Thomas Record, Irina Artsimovitch

Biomolecules· May 2015

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