Publications by authors named "Emily Geddes"

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Transfer learning enables discovery of sub-micromolar antibacterials for ESKAPE pathogens from ultra-large chemical spaces.
Miguel García-Ortegón, Srijit Seal, Emily Geddes, Jenny L Littler, Collette S Guy

Chem Sci· November 2025

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Cell-Based Assay to Determine Type 3 Secretion System Translocon Assembly in Using Split Luciferase.
Hanling Guo, Emily J Geddes, Timothy J Opperman, Alejandro P Heuck

ACS Infect Dis· December 2023

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Porin-independent accumulation in Pseudomonas enables antibiotic discovery.
Emily J Geddes, Morgan K Gugger, Alfredo Garcia, Martin Garcia Chavez, Myung Ryul Lee

Nature· December 2023

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Correction to "An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with Efficacy against Drug-Resistant Gram-Negative Infections".
Erica N Parker, Brett N Cain, Behnoush Hajian, Rebecca J Ulrich, Emily J Geddes

ACS Cent Sci· September 2022

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Rationalizing the generation of broad spectrum antibiotics with the addition of a positive charge.
Nandan Haloi, Archit Kumar Vasan, Emily J Geddes, Arjun Prasanna, Po-Chao Wen

Chem Sci· November 2021

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An LC-MS/MS assay and complementary web-based tool to quantify and predict compound accumulation in E. coli.
Emily J Geddes, Zhong Li, Paul J Hergenrother

Nat Protoc· October 2021

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Compound Uptake into Can Be Facilitated by -Alkyl Guanidiniums and Pyridiniums.
Sarah J Perlmutter, Emily J Geddes, Bryon S Drown, Stephen E Motika, Myung Ryul Lee

ACS Infect Dis· January 2021

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Gram-Negative Antibiotic Active Through Inhibition of an Essential Riboswitch.
Stephen E Motika, Rebecca J Ulrich, Emily J Geddes, Hyang Yeon Lee, Gee W Lau

J Am Chem Soc· June 2020

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Implementation of permeation rules leads to a FabI inhibitor with activity against Gram-negative pathogens.
Erica N Parker, Bryon S Drown, Emily J Geddes, Hyang Yeon Lee, Nahed Ismail

Nat Microbiol· January 2020

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