Publications by authors named "Emily Hartwell"

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Transdiagnostic and Disorder-Level Genome-Wide Association Studies Enhance Precision of Substance Use and Psychiatric Genetic Risk Profiles in African and European Ancestries.
Yousef Khan, Christal N Davis, Zeal Jinwala, Kyra L Feuer, Sylvanus Toikumo, Emily E Hartwell

Biol Psychiatry· January 2026

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Demographic and Genetic Predictors of ADHD Diagnoses and Medications in Electronic Health Records.
Olivia R Nicastro, Makayla Reed, Zeal Jinwala, , , Emily E Hartwell

Res Sq· October 2025

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Predicting treatment-seeking status for alcohol use disorder using polygenic scores and machine learning in a deeply-phenotyped sample.
Zeal Jinwala, ReJoyce Green, Yousef Khan, Joel Gelernter, Rachel L Kember, Emily E Hartwell

Drug Alcohol Depend· September 2025

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Multi-ancestry genome-wide association meta-analysis of buprenorphine treatment response.
Christal N Davis, Yousef Khan, Richard C Crist, Rachel Vickers-Smith, Emily E Hartwell

Neuropsychopharmacology· August 2025

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Next-generation biomarkers for alcohol consumption and alcohol use disorder diagnosis, prognosis, and treatment: A critical review.
Shaunna L Clark, Emily E Hartwell, Doo-Sup Choi, John H Krystal, Robert O Messing

Alcohol Clin Exp Res (Hoboken)· January 2025

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Utility of Candidate Genes From an Algorithm Designed to Predict Genetic Risk for Opioid Use Disorder.
Christal N Davis, Zeal Jinwala, Alexander S Hatoum, Sylvanus Toikumo, Arpana Agrawal, Emily E Hartwell

JAMA Netw Open· January 2025

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Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and somatic traits.
Emily E Hartwell, Zeal Jinwala, Jackson Milone, Sarah Ramirez, Joel Gelernter

Neuropsychopharmacology· December 2024

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Predicting Treatment-seeking Status for Alcohol Use Disorder Using Polygenic Scores and Machine Learning in a Deeply-Phenotyped Sample.
Zeal Jinwala, ReJoyce Green, Yousef Khan, Joel Gelernter, Rachel L Kember, Emily E Hartwell

medRxiv· November 2024

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Gene × environment effects and mediation involving adverse childhood events, mood and anxiety disorders, and substance dependence.
Henry R Kranzler, Christal N Davis, Richard Feinn, Zeal Jinwala, Yousef Khan, Emily E Hartwell

Nat Hum Behav· August 2024

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Author Correction: A multi-ancestry genetic study of pain intensity in 598,339 veterans.
Sylvanus Toikumo, Rachel Vickers-Smith, Zeal Jinwala, Heng Xu, Divya Saini, Emily E Hartwell

Nat Med· July 2024

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Identifying neurofunctional domains across substance use disorders.
Emily E Hartwell, Melanie Schwandt, Yaira Z Nunez, Reagan R Wetherill, Rachel L Kember

Am J Drug Alcohol Abuse· July 2024

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Combining Transdiagnostic and Disorder-Level GWAS Enhances Precision of Psychiatric Genetic Risk Profiles in a Multi-Ancestry Sample.
Yousef Khan, Christal N Davis, Zeal Jinwala, Kyra L Feuer, Sylvanus Toikumo, Emily E Hartwell

medRxiv· May 2024

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Candidate Genes from an FDA-Approved Algorithm Fail to Predict Opioid Use Disorder Risk in Over 450,000 Veterans.
Christal N Davis, Zeal Jinwala, Alexander S Hatoum, Sylvanus Toikumo, Arpana Agrawal, Emily E Hartwell

medRxiv· May 2024

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A multi-ancestry genetic study of pain intensity in 598,339 veterans.
Sylvanus Toikumo, Rachel Vickers-Smith, Zeal Jinwala, Heng Xu, Divya Saini, Emily E Hartwell

Nat Med· April 2024

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Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and medical traits.
Emily E Hartwell, Zeal Jinwala, Jackson Milone, Sarah Ramirez, Joel Gelernter

medRxiv· January 2024

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Adverse Childhood Events, Mood and Anxiety Disorders, and Substance Dependence: Gene X Environment Effects and Moderated Mediation.
Henry R Kranzler, Christal N Davis, Richard Feinn, Zeal Jinwala, Yousef Khan, Emily E Hartwell

medRxiv· October 2023

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Adverse Childhood Events, Mood and Anxiety Disorders, and Substance Dependence: Gene x Environment Effects and Moderated Mediation.
Henry Kranzler, Christal Davis, Richard Feinn, Zeal Jinwala, Yousef Khan, Emily Hartwell

Res Sq· October 2023

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Does polygenic risk for substance-related traits predict ages of onset and progression of symptoms?
Henry R Kranzler, Richard Feinn, Heng Xu, Brendan L Ho, Divya Saini, Emily E Hartwell

Addiction· September 2023

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Medications for treating alcohol use disorder: A narrative review.
Henry R Kranzler, Emily E Hartwell

Alcohol Clin Exp Res (Hoboken)· July 2023

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Racial and Ethnic Bias in the Diagnosis of Alcohol Use Disorder in Veterans.
Rachel Vickers-Smith, Amy C Justice, William C Becker, Christopher T Rentsch, Brenda Curtis, Emily E Hartwell

Am J Psychiatry· June 2023

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Phenome-wide Association Analysis of Substance Use Disorders in a Deeply Phenotyped Sample.
Rachel L Kember, Emily E Hartwell, Heng Xu, James Rotenberg, Laura Almasy

Biol Psychiatry· March 2023

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Effects of topiramate therapy on serum bicarbonate concentration in a sample of 10,279 veterans.
Michelle S Naps, Shirley H Leong, Emily E Hartwell, Christopher T Rentsch, Henry R Kranzler

Alcohol Clin Exp Res (Hoboken)· March 2023

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The genetic architecture of pain intensity in a sample of 598,339 U.S. veterans.
Sylvanus Toikumo, Rachel Vickers-Smith, Zeal Jinwala, Heng Xu, Divya Saini, Emily Hartwell

medRxiv· March 2023

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Treating Alcohol Use Disorder With Hallucinogens-Renewed Interest After a 50-Year Hiatus.
Henry R Kranzler, Emily E Hartwell

JAMA Psychiatry· October 2022

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Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects in brain regions associated with addiction.
Rachel L Kember, Rachel Vickers-Smith, Heng Xu, Sylvanus Toikumo, Maria Niarchou, Emily E Hartwell

Nat Neurosci· October 2022

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