Publications by authors named "Emily Machiela"

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Identification of Novel Therapeutic Targets for Polyglutamine Diseases That Target Mitochondrial Fragmentation.
Annika Traa, Emily Machiela, Paige D Rudich, Sonja K Soo, Megan M Senchuk

Int J Mol Sci· December 2021

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Targeting Mitochondrial Network Disorganization is Protective in Models of Huntington's Disease.
Emily Machiela, Paige D Rudich, Annika Traa, Ulrich Anglas, Sonja K Soo

Aging Dis· October 2021

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Biological Aging and the Cellular Pathogenesis of Huntington's Disease.
Emily Machiela, Amber L Southwell

J Huntingtons Dis· April 2021

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The Interaction of Aging and Cellular Stress Contributes to Pathogenesis in Mouse and Human Huntington Disease Neurons.
Emily Machiela, Ritika Jeloka, Nicholas S Caron, Shagun Mehta, Mandi E Schmidt

Front Aging Neurosci· September 2020

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Disruption of mitochondrial dynamics increases stress resistance through activation of multiple stress response pathways.
Emily Machiela, Thomas Liontis, Dylan J Dues, Paige D Rudich, Annika Traa

FASEB J· June 2020

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Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways.
Ziyun Wu, Megan M Senchuk, Dylan J Dues, Benjamin K Johnson, Jason F Cooper, Emily Machiela

BMC Biol· December 2018

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Activation of the mitochondrial unfolded protein response promotes longevity and dopamine neuron survival in Parkinson's disease models.
Jason F Cooper, Emily Machiela, Dylan J Dues, Katie K Spielbauer, Megan M Senchuk

Sci Rep· November 2017

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Oxidative stress is increased in C. elegans models of Huntington's disease but does not contribute to polyglutamine toxicity phenotypes.
Emily Machiela, Dylan J Dues, Megan M Senchuk, Jeremy M Van Raamsdonk

Neurobiol Dis· December 2016

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Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson's disease.
Anamitra Ghosh, Trevor Tyson, Sonia George, Erin N Hildebrandt, Jennifer A Steiner, Emily Machiela

Sci Transl Med· December 2016

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Delaying aging is neuroprotective in Parkinson's disease: a genetic analysis in models.
Jason F Cooper, Dylan J Dues, Katie K Spielbauer, Emily Machiela, Megan M Senchuk

NPJ Parkinsons Dis· November 2015

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Mitochondrial and cytoplasmic ROS have opposing effects on lifespan.
Claire E Schaar, Dylan J Dues, Katie K Spielbauer, Emily Machiela, Jason F Cooper

PLoS Genet· February 2015

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