Publications by authors named "Emily Nettesheim"

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First-in-human high dose AAV9 intrathecal gene therapy for paediatric CLN7 disease: a phase 1, open-label, single ascending dose, non-randomised clinical trial.
Benjamin M Greenberg, Berge Minassian, Souad Messahel, Veronica Bordes Edgar, Andrea Lowden, Emily R Nettesheim

EBioMedicine· November 2025

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Elevated PRDM13 Disrupts Photoreceptor Function and Survival in the Mammalian Retina.
Emily R Nettesheim, Ashley A Rowe, Tiffany Yee, Ahmed Alshaikhsalama, Tyler Cepica

Invest Ophthalmol Vis Sci· August 2025

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Female sex hormones exacerbate retinal neurodegeneration.
Ashley A Rowe, Mauricio J Velasquez, Jacob W Aumeier, Sofia Reyes, Tiffany Yee, Emily R Nettesheim

Sci Adv· April 2025

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Neuronal ceroid lipofuscinoses type 7 (CLN7): a case series reporting cross sectional and retrospective clinical data to evaluate validity of standardized tools to assess disease progression, quality of life, and adaptive skills.
Saima Kayani, Veronica BordesEdgar, Andrea Lowden, Emily R Nettesheim, Hamza Dahshi

Orphanet J Rare Dis· December 2024

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Female sex hormones exacerbate retinal neurodegeneration.
Ashley A Rowe, Sofia Reyes, Mauricio J Velasquez, Tiffany Yee, Emily R Nettesheim

bioRxiv· July 2024

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Neuronal Ceroid Lipofuscinoses Type 7 (CLN7)- A Case Series Reporting Cross Sectional and Retrospective Clinical Data to Evaluate Validity of Standardized Tools to Assess Disease Progression, Quality of Life, and Adaptive Skills.
Saima Kayani, Veronica Bordes Edgar, Andrea Lowden, Emily R Nettesheim, Hamza Dahshi

Res Sq· June 2024

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Improved Cardiac Function in Postischemic Rats Using an Optimized Cardiac Reprogramming Cocktail Delivered in a Single Novel Adeno-Associated Virus.
Huanyu Zhou, Jin Yang, Chetan Srinath, Aliya Zeng, Iris Wu, Emily R Nettesheim

Circulation· October 2023

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Prostaglandin-based rAAV-mediated glaucoma gene therapy in Brown Norway rats.
Kristina J Chern, Emily R Nettesheim, Christopher A Reid, Nathan W Li, Gavin J Marcoe

Commun Biol· November 2022

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Long-term progression of retinal degeneration in a preclinical model of CLN7 Batten disease as a baseline for testing clinical therapeutics.
Ashley A Rowe, Xin Chen, Emily R Nettesheim, Yacine Issioui, Thomas Dong

EBioMedicine· November 2022

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PA licensure questions, the Americans with Disabilities Act, and seeking medical care.
Christopher Roman, Stephanie Neary, Emily Nettesheim, Jennifer Zorn

JAAPA· January 2022

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Do PA licensure questions violate the Americans with Disabilities Act?
Emily Nettesheim, Stephanie Neary, Christopher Roman

JAAPA· March 2021

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A candidate activation pathway for coagulation factor VII.
Tina M Misenheimer, Kraig T Kumfer, Barbara E Bates, Emily R Nettesheim, Bradford S Schwartz

Biochem J· October 2019

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Presynaptic Expression of LRIT3 Transsynaptically Organizes the Postsynaptic Glutamate Signaling Complex Containing TRPM1.
Nazarul Hasan, Gobinda Pangeni, Catherine A Cobb, Thomas A Ray, Emily R Nettesheim

Cell Rep· June 2019

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A Destabilizing Domain Allows for Fast, Noninvasive, Conditional Control of Protein Abundance in the Mouse Eye - Implications for Ocular Gene Therapy.
Shyamtanu Datta, Marian Renwick, Viet Q Chau, Fang Zhang, Emily R Nettesheim

Invest Ophthalmol Vis Sci· October 2018

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Development of an inducible anti-VEGF rAAV gene therapy strategy for the treatment of wet AMD.
Christopher A Reid, Emily R Nettesheim, Thomas B Connor, Daniel M Lipinski

Sci Rep· August 2018

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