Publications by authors named "Emma Derrett-Smith"

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Transforming growth factor beta (TGF-β) induces type 1 interferon signalling in systemic sclerosis keratinocytes through the chloride intracellular channel 4 (CLIC4).
Christopher W Wasson, Sophie L Dibb, Begoña Caballero-Ruiz, Ifeoluwa E Bamigbola, Stefano Di Donato, Emma Derrett-Smith

Arthritis Res Ther· September 2025

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The 2024 British Society for Rheumatology guideline for management of systemic sclerosis-executive summary.
Christopher P Denton, Enrico De Lorenzis, Elen Roblin, Nina Goldman, Begonya Alcacer-Pitarch, Emma Derrett-Smith

Rheumatology (Oxford)· November 2024

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The 2024 British Society for Rheumatology guideline for management of systemic sclerosis.
Christopher P Denton, Enrico De Lorenzis, Elen Roblin, Nina Goldman, Begonya Alcacer-Pitarch, Emma Derrett-Smith

Rheumatology (Oxford)· November 2024

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Clinical trajectories of hand function impairment in systemic sclerosis: an unmet clinical need across disease subsets.
Enrico De Lorenzis, Vishal Kakkar, Stefano Di Donato, Michelle Wilson, Theresa Barnes, Emma Derrett-Smith

RMD Open· January 2024

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Skin biopsy analysis of concurrent keloidal morphoea and systemic sclerosis confirms overlapping pathogenic pathways.
Kristina E N Clark, Nataliya Gak, Catherine H Orteu, Voon H Ong, Emma C Derrett-Smith

Clin Exp Rheumatol· August 2023

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The value of ultrasound-defined tenosynovitis and synovitis in the prediction of persistent arthritis.
Ilfita Sahbudin, Ruchir Singh, Paola De Pablo, Elizabeth Rankin, Benjamin Rhodes, Emma Derrett-Smith

Rheumatology (Oxford)· March 2023

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Management of systemic sclerosis: British Society for Rheumatology guideline scope.
Christopher P Denton, Enrico De Lorenzis, Elen Roblin, Nina Goldman, Begonya Alcacer-Pitarch, Emma Derrett-Smith

Rheumatol Adv Pract· March 2023

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A genomic meta-analysis of clinical variables and their association with intrinsic molecular subsets in systemic sclerosis.
Jennifer M Franks, Diana M Toledo, Viktor Martyanov, Yue Wang, Suiyuan Huang, Emma Derrett-Smith

Rheumatology (Oxford)· December 2022

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Integrated analysis of dermal blister fluid proteomics and genome-wide skin gene expression in systemic sclerosis: an observational study.
Kristina E N Clark, Eszter Csomor, Corrado Campochiaro, Nicholas Galwey, Katherine Nevin, Emma Derrett-Smith

Lancet Rheumatol· July 2022

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Outcomes linked to eligibility for stem cell transplantation trials in diffuse cutaneous systemic sclerosis.
Julia Spierings, Svetlana I Nihtyanova, Emma Derrett-Smith, Kristina E N Clark, Jacob M van Laar

Rheumatology (Oxford)· May 2022

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Induction of Pro-Fibrotic CLIC4 in Dermal Fibroblasts by TGF-β/Wnt3a Is Mediated by GLI2 Upregulation.
Christopher W Wasson, Begoña Caballero-Ruiz, Justin Gillespie, Emma Derrett-Smith, Jamel Mankouri

Cells· February 2022

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Molecular basis for clinical diversity between autoantibody subsets in diffuse cutaneous systemic sclerosis.
Kristina Elizabeth Neergaard Clark, Corrado Campochiaro, Eszter Csomor, Adam Taylor, Katherine Nevin, Emma Derrett-Smith

Ann Rheum Dis· December 2021

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The pan-PPAR agonist lanifibranor reduces development of lung fibrosis and attenuates cardiorespiratory manifestations in a transgenic mouse model of systemic sclerosis.
Emma Derrett-Smith, Kristina E N Clark, Xu Shiwen, David J Abraham, Rachel K Hoyles

Arthritis Res Ther· September 2021

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Using Autoantibodies and Cutaneous Subset to Develop Outcome-Based Disease Classification in Systemic Sclerosis.
Svetlana I Nihtyanova, Alper Sari, Jennifer C Harvey, Anna Leslie, Emma C Derrett-Smith

Arthritis Rheumatol· March 2020

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Transforming Growth Factor β Activation Primes Canonical Wnt Signaling Through Down-Regulation of Axin-2.
Justin Gillespie, Rebecca L Ross, Clarissa Corinaldesi, Filomena Esteves, Emma Derrett-Smith

Arthritis Rheumatol· June 2018

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What does it mean if a patient is positive for anti-Jo-1 in routine hospital practice? A retrospective nested case-control study.
Paresh Jobanputra, Feryal Malick, Emma Derrett-Smith, Tim Plant, Alex Richter

F1000Res· June 2018

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Scleroderma fibroblasts suppress angiogenesis via TGF-β/caveolin-1 dependent secretion of pigment epithelium-derived factor.
Vasiliki Liakouli, Jacobo Elies, Yasser Mohamed El-Sherbiny, Margherita Scarcia, Gary Grant, Emma C Derrett-Smith

Ann Rheum Dis· March 2018

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Limited cutaneous systemic sclerosis skin demonstrates distinct molecular subsets separated by a cardiovascular development gene expression signature.
Emma C Derrett-Smith, Viktor Martyanov, Cecilia B Chighizola, Pia Moinzadeh, Corrado Campochiaro

Arthritis Res Ther· July 2017

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Resolution of paraneoplastic PM/Scl-positive systemic sclerosis after curative resection of a pancreatic tumour.
Cosimo Bruni, Ana Lages, Hitesh Patel, Svetlana I Nihtyanova, Bryan Green, Emma Derrett-Smith

Rheumatology (Oxford)· February 2017

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Impaired bone morphogenetic protein receptor II signaling in a transforming growth factor-β-dependent mouse model of pulmonary hypertension and in systemic sclerosis.
Adrian J Gilbane, Emma Derrett-Smith, Sarah L Trinder, Robert B Good, Andrew Pearce

Am J Respir Crit Care Med· March 2015

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Endothelial injury in a transforming growth factor β-dependent mouse model of scleroderma induces pulmonary arterial hypertension.
Emma C Derrett-Smith, Audrey Dooley, Adrian J Gilbane, Sarah L Trinder, Korsa Khan

Arthritis Rheum· November 2013

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Revisiting ANCA-associated vasculitis in systemic sclerosis: clinical, serological and immunogenetic factors.
Emma C Derrett-Smith, Svetlana I Nihtyanova, Jennifer Harvey, Alan D Salama, Christopher P Denton

Rheumatology (Oxford)· October 2013

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Gut fibrosis with altered colonic contractility in a mouse model of scleroderma.
Nora M Thoua, Emma C Derrett-Smith, Korsa Khan, Audrey Dooley, Xu Shi-Wen

Rheumatology (Oxford)· November 2012

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Clinical and pathological significance of interleukin 6 overexpression in systemic sclerosis.
Korsa Khan, Shiwen Xu, Svetlana Nihtyanova, Emma Derrett-Smith, David Abraham

Ann Rheum Dis· July 2012

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An essential role for resident fibroblasts in experimental lung fibrosis is defined by lineage-specific deletion of high-affinity type II transforming growth factor β receptor.
Rachel K Hoyles, Emma C Derrett-Smith, Korsa Khan, Xu Shiwen, Sarah L Howat

Am J Respir Crit Care Med· January 2011

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