Publications by authors named "Emma Lofthouse"

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Computational Modelling of Paracellular Diffusion and OCT3 Mediated Transport of Metformin in the Perfused Human Placenta.
Emma M Lofthouse, Jane Cleal, Rohan M Lewis, Bram G Sengers

J Pharm Sci· September 2023

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3D visualization of trans-syncytial nanopores provides a pathway for paracellular diffusion across the human placental syncytiotrophoblast.
Rohan M Lewis, Harikesan Baskaran, Jools Green, Stanimir Tashev, Eleni Palaiologou, Emma M Lofthouse

iScience· December 2022

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Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit.
Brogan Ashley, Claire Simner, Antigoni Manousopoulou, Carl Jenkinson, Felicity Hey, Emma M Lofthouse

Elife· March 2022

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Folding of the syncytiotrophoblast basal plasma membrane increases the surface area available for exchange in human placenta.
Stanimir A Tashev, Daisy Parsons, Cameron Hillman, Shelley Harris, Emma M Lofthouse

Placenta· January 2022

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N-acetylcysteine, xCT and suppression of Maxi-chloride channel activity in human placenta.
Emma M Lofthouse, Antigoni Manousopoulou, Jane K Cleal, Ita M O'Kelly, Kirsten R Poore

Placenta· July 2021

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Pericytes on placental capillaries in terminal villi preferentially cover endothelial junctions in regions furthest away from the trophoblast.
Shelley E Harris, Kate Sh Matthews, Eleni Palaiologou, Stanimir A Tashev, Emma M Lofthouse

Placenta· January 2021

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Glibenclamide transfer across the perfused human placenta is determined by albumin binding not transporter activity.
Emma M Lofthouse, Jane K Cleal, Georgina Hudson, Rohan M Lewis, Bram G Sengers

Eur J Pharm Sci· September 2020

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Serial block-face scanning electron microscopy reveals novel intercellular connections in human term placental microvasculature.
Eleni Palaiologou, Patricia Goggin, David S Chatelet, Rodolfo Ribeiro de Souza, Wendy Chiu, Emma M Lofthouse

J Anat· August 2020

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Ursodeoxycholic acid inhibits uptake and vasoconstrictor effects of taurocholate in human placenta.
Emma M Lofthouse, Christopher Torrens, Antigoni Manousopoulou, Monica Nahar, Jane K Cleal

FASEB J· July 2019

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A systems perspective on placental amino acid transport.
Jane K Cleal, Emma M Lofthouse, Bram G Sengers, Rohan M Lewis

J Physiol· December 2018

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Estrone sulphate uptake by the microvillous membrane of placental syncytiotrophoblast is coupled to glutamate efflux.
Emma M Lofthouse, Jane K Cleal, Ita M O'Kelly, Bram G Sengers, Rohan M Lewis

Biochem Biophys Res Commun· November 2018

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Serial block-face scanning electron microscopy of erythrocytes protruding through the human placental syncytiotrophoblast.
Eleni Palaiologou, Patricia Goggin, David S Chatelet, Emma M Lofthouse, Christopher Torrens

J Anat· October 2017

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Glutamate cycling may drive organic anion transport on the basal membrane of human placental syncytiotrophoblast.
Emma M Lofthouse, Suzanne Brooks, Jane K Cleal, Mark A Hanson, Kirsten R Poore

J Physiol· October 2015

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Systems-based approaches to probing metabolic variation within the Mycobacterium tuberculosis complex.
Emma K Lofthouse, Paul R Wheeler, Dany J V Beste, Bhagwati L Khatri, Huihai Wu

PLoS One· June 2014

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A patient with bacteraemia and possible endocarditis caused by a recently-discovered genomospecies of Capnocytophaga: Capnocytophaga genomospecies AHN8471: a case report.
Jonathan M Mills, Emma Lofthouse, Phil Roberts, Johannis A Karas

J Med Case Rep· December 2008

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