Publications by authors named "Emma Mead"

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Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor.
Darragh P O'Brien, Hannah B L Jones, Yuqi Shi, Franziska Guenther, Iolanda Vendrell, Emma Mead

J Proteome Res· February 2025

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Evaluating data integrity in ribosome footprinting datasets through modelled polysome profiles.
Fabio Hedayioglu, Emma J Mead, Patrick B F O'Connor, Matas Skiotys, Owen J Sansom

Nucleic Acids Res· October 2022

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Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.
Aleksandra Szykowska, Yu Chen, Thomas B Smith, Charlotta Preger, Jingjing Yang, Emma Mead

Structure· November 2021

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PLCγ2 regulates TREM2 signalling and integrin-mediated adhesion and migration of human iPSC-derived macrophages.
Juliane Obst, Hazel L Hall-Roberts, Thomas B Smith, Mira Kreuzer, Lorenza Magno, Emma Mead

Sci Rep· October 2021

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TREM2/PLCγ2 signalling in immune cells: function, structural insight, and potential therapeutic modulation.
Lorenza Magno, Tom D Bunney, Emma Mead, Fredrik Svensson, Magda N Bictash

Mol Neurodegener· April 2021

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Amyloid binding and beyond: a new approach for Alzheimer's disease drug discovery targeting Aβo-PrP binding and downstream pathways.
James D Grayson, Matthew P Baumgartner, Cleide Dos Santos Souza, Samuel J Dawes, Imane Ghafir El Idrissi, Emma Mead

Chem Sci· February 2021

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TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages.
Hazel Hall-Roberts, Devika Agarwal, Juliane Obst, Thomas B Smith, Jimena Monzón-Sandoval, Emma Mead

Alzheimers Res Ther· November 2020

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Control of translation elongation in health and disease.
John R P Knight, Gavin Garland, Tuija Pöyry, Emma Mead, Nikola Vlahov

Dis Model Mech· March 2020

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Application of ER Stress Biomarkers to Predict Formulated Monoclonal Antibody Stability.
Natalie E Talbot, Emma J Mead, Stephanie A Davies, Shahid Uddin, C Mark Smales

Biotechnol J· October 2019

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Correction: Interventions for treating children and adolescents with overweight and obesity: an overview of Cochrane reviews.
Louisa J Ells, Karen Rees, Tamara Brown, Emma Mead, Lena Al-Khudairy

Int J Obes (Lond)· August 2019

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Behavior-Changing Interventions for Treating Overweight or Obesity in Children Aged 6 to 11 Years.
Tamara J Brown, Emma Mead, Louisa J Ells

JAMA Pediatr· April 2019

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Interventions for treating children and adolescents with overweight and obesity: an overview of Cochrane reviews.
Louisa J Ells, Karen Rees, Tamara Brown, Emma Mead, Lena Al-Khudairy

Int J Obes (Lond)· November 2018

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Polysome profiling of mAb producing CHO cell lines links translational control of cell proliferation and recombinant mRNA loading onto ribosomes with global and recombinant protein synthesis.
Charlotte L Godfrey, Emma J Mead, Olalekan Daramola, Sarah Dunn, Diane Hatton

Biotechnol J· August 2017

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Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age of 6 to 11 years.
Emma Mead, Tamara Brown, Karen Rees, Liane B Azevedo, Victoria Whittaker

Cochrane Database Syst Rev· June 2017

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Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents aged 12 to 17 years.
Lena Al-Khudairy, Emma Loveman, Jill L Colquitt, Emma Mead, Rebecca E Johnson

Cochrane Database Syst Rev· June 2017

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Drug interventions for the treatment of obesity in children and adolescents.
Emma Mead, Greg Atkinson, Bernd Richter, Maria-Inti Metzendorf, Louise Baur

Cochrane Database Syst Rev· November 2016

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Halting of Caspase Activity Protects Tau from MC1-Conformational Change and Aggregation.
Emma Mead, Dimitra Kestoras, Yolanda Gibson, Lucy Hamilton, Ross Goodson

J Alzheimers Dis· October 2016

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Diet, physical activity, and behavioural interventions for the treatment of overweight or obesity in preschool children up to the age of 6 years.
Jill L Colquitt, Emma Loveman, Claire O'Malley, Liane B Azevedo, Emma Mead

Cochrane Database Syst Rev· March 2016

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Biological insights into the expression of translation initiation factors from recombinant CHOK1SV cell lines and their relationship to enhanced productivity.
Emma J Mead, Rosalyn J Masterton, Marc Feary, Olga Obrezanova, Lin Zhang

Biochem J· December 2015

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Parent-only interventions for childhood overweight or obesity in children aged 5 to 11 years.
Emma Loveman, Lena Al-Khudairy, Rebecca E Johnson, Wendy Robertson, Jill L Colquitt, Emma L Mead

Cochrane Database Syst Rev· December 2015

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Prevalence of severe childhood obesity in England: 2006-2013.
Louisa J Ells, Caroline Hancock, Vicky R Copley, Emma Mead, Hywell Dinsdale

Arch Dis Child· July 2015

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Surgery for the treatment of obesity in children and adolescents.
Louisa J Ells, Emma Mead, Greg Atkinson, Eva Corpeleijn, Katharine Roberts

Cochrane Database Syst Rev· June 2015

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Control and regulation of mRNA translation.
Emma J Mead, Rosalyn J Masterton, Tobias von der Haar, Mick F Tuite, C Mark Smales

Biochem Soc Trans· February 2014

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Experimental and in silico modelling analyses of the gene expression pathway for recombinant antibody and by-product production in NS0 cell lines.
Emma J Mead, Lesley M Chiverton, Sarah K Spurgeon, Elaine B Martin, Gary A Montague

PLoS One· February 2013

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Microglial neurotransmitter receptors trigger superoxide production in microglia; consequences for microglial-neuronal interactions.
Emma L Mead, Angelina Mosley, Simon Eaton, Lucianne Dobson, Simon J Heales

J Neurochem· April 2012

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