Publications by authors named "Emma Plested"

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Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine in children aged 6-17 years: Final results of a phase 2, single-blind, randomised controlled trial (COV006).
Grace Li, Natalie G Marchevsky, Grace Macaulay, Parvinder Aley, Hannah Baughan, Emma Plested

Vaccine· August 2025

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Understanding the interaction of upper respiratory tract infection with respiratory syncytial virus and Streptococcus pneumoniae using a human challenge model: a multicenter, randomized controlled study protocol.
Sanjita Brito-Mutunayagam, David O Hamilton, Elena Mitsi, Carla Solórzano, Grace Li, Emma Plested

PLoS One· July 2025

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A phase 1/2a clinical trial to assess safety and immunogenicity of an adenoviral-vectored capsular group B meningococcal vaccine.
Christina Dold, Blanché Oguti, Laura Silva-Reyes, Anna Stanzelova, Meriel Raymond, Emma Plested

Sci Transl Med· May 2025

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Pneumococcal Carriage and Disease in Adults in England, 2011-2019: The Importance of Adults as a Reservoir for Pneumococcus in Communities.
Dima El Safadi, Lisa Hitchins, Ashleigh Howard, Parvinder Aley, Jaclyn Bowman, Emma Plested

J Infect Dis· February 2025

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Safety and humoral immunogenicity of the ChAdOx1 nCoV-19 vaccine administered as a fourth dose booster following two doses of ChAdOx1 nCoV-19 and a third dose of BNT162b2 (COV009): A prospective cohort study.
Shuo Feng, Sagida Bibi, Parvinder K Aley, Federica Cappuccini, Elizabeth A Clutterbuck, Emma Plested

J Infect· February 2025

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The Impact of Infant Bacille Calmette-Guérin Vaccination on the Immunogenicity of Other Vaccines: A Randomized Exploratory Study.
Alexander Maytum, David Porter, Philip de Whalley, Amber Thompson, Emma Plested

Pediatr Infect Dis J· August 2024

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Serum HCoV-spike specific antibodies do not protect against subsequent SARS-CoV-2 infection in children and adolescents.
Helen Ratcliffe, Karen S Tiley, Stephanie Longet, Claire Tonry, Cathal Roarty, Emma Plested

iScience· December 2023

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Reactogenicity, immunogenicity and breakthrough infections following heterologous or fractional second dose COVID-19 vaccination in adolescents (Com-COV3): A randomised controlled trial.
Eimear Kelly, Melanie Greenland, Philip C S de Whalley, Parvinder K Aley, Emma L Plested

J Infect· September 2023

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Persistence of immune response in heterologous COVID vaccination schedules in the Com-COV2 study - A single-blind, randomised trial incorporating mRNA, viral-vector and protein-adjuvant vaccines.
Robert H Shaw, Melanie Greenland, Arabella S V Stuart, Parvinder K Aley, Nick J Andrews, Emma L Plested

J Infect· June 2023

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Pneumococcal carriage following PCV13 delivered as one primary and one booster dose (1 + 1) compared to two primary doses and a booster (2 + 1) in UK infants.
David Goldblatt, Nick J Andrews, Carmen L Sheppard, Samuel Rose, Parvinder K Aley, Emma Plested

Vaccine· May 2023

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Nasopharyngeal Carriage of Pneumococcus in Children in England up to 10 Years After 13-Valent Pneumococcal Conjugate Vaccine Introduction: Persistence of Serotypes 3 and 19A and Emergence of 7C.
Karen S Tiley, Helen Ratcliffe, Merryn Voysey, Kimberley Jefferies, Gemma Sinclair, Emma Plested

J Infect Dis· March 2023

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Persistence of the immune response after two doses of ChAdOx1 nCov-19 (AZD1222): 1 year of follow-up of two randomized controlled trials.
Merryn Voysey, Amy Flaxman, Jeremy Aboagye, Parvinder K Aley, Sandra Belij-Rammerstorfer, Emma Plested

Clin Exp Immunol· March 2023

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Community seroprevalence of SARS-CoV-2 in children and adolescents in England, 2019-2021.
Helen Ratcliffe, K S Tiley, Nick Andrews, Gayatri Amirthalingam, I Vichos, Emma Plested

Arch Dis Child· January 2023

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Booster Vaccination Against SARS-CoV-2 Induces Potent Immune Responses in People With Human Immunodeficiency Virus.
Sarah Fidler, Julie Fox, Timothy Tipoe, Stephanie Longet, Tom Tipton, Emma Plested

Clin Infect Dis· January 2023

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Impact of meningococcal ACWY conjugate vaccines on pharyngeal carriage in adolescents: evidence for herd protection from the UK MenACWY programme.
Jeremy P Carr, Jenny M MacLennan, Emma Plested, Holly B Bratcher, Odile B Harrison

Clin Microbiol Infect· December 2022

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Effect of priming interval on reactogenicity, peak immunological response, and waning after homologous and heterologous COVID-19 vaccine schedules: exploratory analyses of Com-COV, a randomised control trial.
Robert H Shaw, Xinxue Liu, Arabella S V Stuart, Melanie Greenland, Parvinder K Aley, Emma L Plested

Lancet Respir Med· November 2022

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An exploratory analysis of the response to ChAdOx1 nCoV-19 (AZD1222) vaccine in males and females.
Natalie Gabrielle Marchevsky, Grace Li, Parvinder Aley, Sue Ann Costa Clemens, Jordan Richard Barrett, Emma Plested

EBioMedicine· July 2022

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Durability of ChAdOx1 nCoV-19 vaccination in people living with HIV.
Ane Ogbe, Matthew Pace, Mustapha Bittaye, Timothy Tipoe, Sandra Adele, Emma Plested

JCI Insight· April 2022

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Immunogenicity, safety, and reactogenicity of heterologous COVID-19 primary vaccination incorporating mRNA, viral-vector, and protein-adjuvant vaccines in the UK (Com-COV2): a single-blind, randomised, phase 2, non-inferiority trial.
Arabella S V Stuart, Robert H Shaw, Xinxue Liu, Melanie Greenland, Parvinder K Aley, Emma L Plested

Lancet· January 2022

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Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection.
Shuo Feng, Daniel J Phillips, Thomas White, Homesh Sayal, Parvinder K Aley, Emma Plested

Nat Med· November 2021

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Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 lineages circulating in Brazil.
Sue Ann Costa Clemens, Pedro M Folegatti, Katherine R W Emary, Lily Yin Weckx, Jeremy Ratcliff, Emma Plested

Nat Commun· October 2021

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Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-inferiority trial.
Xinxue Liu, Robert H Shaw, Arabella S V Stuart, Melanie Greenland, Parvinder K Aley, Emma L Plested

Lancet· September 2021

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Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002).
Amy Flaxman, Natalie G Marchevsky, Daniel Jenkin, Jeremy Aboagye, Parvinder K Aley, Emma Plested

Lancet· September 2021

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Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in HIV infection: a single-arm substudy of a phase 2/3 clinical trial.
John Frater, Katie J Ewer, Ane Ogbe, Mathew Pace, Sandra Adele, Emma Plested

Lancet HIV· August 2021

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Author Correction: T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial.
Katie J Ewer, Jordan R Barrett, Sandra Belij-Rammerstorfer, Hannah Sharpe, Rebecca Makinson, Emma Plested

Nat Med· June 2021

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