Publications by authors named "Emma S Child"

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Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease.
Bo Qin, Gregory B Craven, Pengjiao Hou, Julian Chesti, Xinran Lu, Emma S Child

Acta Pharm Sin B· October 2022

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Inhibition of mitogen-activated protein kinase (MAPK) and cyclin-dependent kinase 2 (Cdk2) by platinum(II) phenanthroline complexes.
Emma S Child, Savvas N Georgiades, Kirsten N Rose, Verity S Stafford, Chirag B K Patel

J Chem Biol· October 2011

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The chemoselective one-step alkylation and isolation of thiophosphorylated cdk2 substrates in the presence of native cysteine.
Sarah E Lee, Lucy M Elphick, Holger B Kramer, Alexandra M E Jones, Emma S Child

Chembiochem· March 2011

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Cyclin D1 and cyclin D3 show divergent responses to distinct mitogenic stimulation.
Alexandra A Anderson, Emma S Child, Aarathi Prasad, Lucy M Elphick, David J Mann

J Cell Physiol· November 2010

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Cell cycle-dependent regulation of the forkhead transcription factor FOXK2 by CDK·cyclin complexes.
Anett Marais, Zongling Ji, Emma S Child, Eberhard Krause, David J Mann

J Biol Chem· November 2010

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A cancer-derived mutation in the PSTAIRE helix of cyclin-dependent kinase 2 alters the stability of cyclin binding.
Emma S Child, Tereza Hendrychová, Karen McCague, Andy Futreal, Michal Otyepka

Biochim Biophys Acta· July 2010

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Dose-dependent changes in cyclin D1 in response to 4-nitroquinoline 1-oxide-induced DNA damage.
Natsuko Suwaki, Emma S Child, Lucy M Elphick, David J Mann

Arch Biochem Biophys· May 2010

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Synthesis and O-phosphorylation of 3,3,4,4-tetrafluoroaryl-C-nucleoside analogues.
Laurent Bonnac, Sarah E Lee, Guy T Giuffredi, Lucy M Elphick, Alexandra A Anderson, Emma S Child

Org Biomol Chem· March 2010

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Exploring the roles of protein kinases using chemical genetics.
Lucy M Elphick, Sarah E Lee, Alexandra A Anderson, Emma S Child, Laurent Bonnac

Future Med Chem· October 2009

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Synthesis and reactivity of novel gamma-phosphate modified ATP analogues.
Sarah E Lee, Lucy M Elphick, Alexandra A Anderson, Laurent Bonnac, Emma S Child

Bioorg Med Chem Lett· July 2009

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A quantitative comparison of wild-type and gatekeeper mutant cdk2 for chemical genetic studies with ATP analogues.
Lucy M Elphick, Sarah E Lee, Emma S Child, Aarathi Prasad, Cristina Pignocchi

Chembiochem· June 2009

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Differential regulation of the cyclin-dependent kinase inhibitors p21(Cip1) and p27(Kip1) by phosphorylation directed by the cyclin encoded by Murine Herpesvirus 68.
Aliaksandr Yarmishyn, Emma S Child, Lucy M Elphick, David J Mann

Exp Cell Res· January 2008

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p27Kip1 and p130 cooperate to regulate hematopoietic cell proliferation in vivo.
Inês Soeiro, Azim Mohamedali, Hanna M Romanska, Nicholas C Lea, Emma S Child

Mol Cell Biol· August 2006

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The intricacies of p21 phosphorylation: protein/protein interactions, subcellular localization and stability.
Emma S Child, David J Mann

Cell Cycle· June 2006

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Phosphorylation of the cyclin-dependent kinase inhibitor p21Cip1 on serine 130 is essential for viral cyclin-mediated bypass of a p21Cip1-imposed G1 arrest.
Annika Järviluoma, Emma S Child, Grzegorz Sarek, Papinya Sirimongkolkasem, Gordon Peters

Mol Cell Biol· March 2006

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H2O2 induces a transient multi-phase cell cycle arrest in mouse fibroblasts through modulating cyclin D and p21Cip1 expression.
Karin Barnouin, Marlène L Dubuisson, Emma S Child, Silvia Fernandez de Mattos, Janet Glassford

J Biol Chem· April 2002

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