Publications by authors named "Emma Vincent"

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Adiposity distribution and risks of 12 obesity-related cancers: a Mendelian randomization analysis.
Emma Hazelwood, Lucy J Goudswaard, Matthew A Lee, Marina Vabistsevits, Dimitri J Pournaras, Emma E Vincent

J Natl Cancer Inst· December 2025

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Canagliflozin synergises with serine restriction mediating anti-leukaemic effects in T-cell acute lymphoblastic leukaemia.
Fernando M Ponce-Garcia, Yasmin R Jenkins, Victoria D Assmann, Silpita Paul, Nitesh D Sharma, Emma E Vincent

Mol Metab· December 2025

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Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function.
Benjamin J Jenkins, Yasmin R Jenkins, Fernando M Ponce-Garcia, Chloe Moscrop, Iain A Perry, Emma E Vincent

Nat Commun· November 2025

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Association between glucosamine use and albuminuria in the UK: a cohort and Mendelian randomisation study.
Samantha Jl Hayward, Andrei Constantinescu, Emma Hazelwood, Matthew J Butler, Emma E Vincent

BMJ Open· November 2025

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Transcriptome-wide Mendelian randomization exploring dynamic CD4+ T cell gene expression in colorectal cancer development.
Benedita Deslandes, Xueyan Wu, Matthew A Lee, Lucy J Goudswaard, Gareth W Jones, Emma E Vincent

J Leukoc Biol· October 2025

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Proteogenomic and observational evidence implicate ANGPTL4 as a potential therapeutic target for colorectal cancer prevention.
James Yarmolinsky, Matthew A Lee, Evelyn Lau, Ferran Moratalla-Navarro, Emma E Vincent

J Natl Cancer Inst· September 2025

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A comprehensive phenome wide analysis of the role of neutrophils in health and disease.
Katy Fleming, Naomi Cornish, Emma E Vincent, Andrew D Mumford, Borko Amulic

J Leukoc Biol· July 2025

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Association of Genetic Liability to Allergic Diseases with Overall and Early-Onset Colorectal Cancer Risk: A Mendelian Randomization Study.
Saleh Alduhayh, Ruhina Shirin Laskar, Xia Jiang, Zhaozhong Zhu, Emma E Vincent

Cancer Epidemiol Biomarkers Prev· May 2025

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Multi-tissue expression and splicing data prioritise anatomical subsite- and sex-specific colorectal cancer susceptibility genes.
Emma Hazelwood, Daffodil M Canson, Benedita Deslandes, Xuemin Wang, Pik Fang Kho, Emma E Vincent

Nat Commun· May 2025

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Transcriptome-wide Mendelian randomisation exploring dynamic CD4+ T cell gene expression in colorectal cancer development.
Benedita Deslandes, Xueyan Wu, Matthew A Lee, Lucy J Goudswaard, Gareth W Jones, Emma E Vincent

medRxiv· April 2025

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ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity.
Benjamin J Jenkins, Yasmin R Jenkins, Fernando M Ponce-Garcia, Chloe Moscrop, Iain A Perry, Emma E Vincent

bioRxiv· March 2025

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Identifying targetable metabolic dependencies across colorectal cancer progression.
Danny N Legge, Tracey J Collard, Ewelina Stanko, Ashley J Hoskin, Amy K Holt, Emma E Vincent

Mol Metab· December 2024

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Plasma Ghrelin and Risks of Sex-Specific, Site-Specific, and Early-Onset Colorectal Cancer: A Mendelian Randomization Analysis.
Emma Hazelwood, Catalina Lopez Manzano, Emma E Vincent, Demetrius Albanes, David Timothy Bishop

Cancer Epidemiol Biomarkers Prev· December 2024

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A proteogenomic analysis of the adiposity colorectal cancer relationship identifies GREM1 as a probable mediator.
Matthew A Lee, Charlie A Hatcher, Emma Hazelwood, Lucy J Goudswaard, Konstantinos K Tsilidis, Emma E Vincent

Int J Epidemiol· December 2024

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Spliceosomal vulnerability of MYCN-amplified neuroblastoma is contingent on PRMT5-mediated regulation of epitranscriptomic and metabolomic pathways.
Jodie Bojko, Madhu Kollareddy, Marianna Szemes, Jacob Bellamy, Evon Poon, Emma E Vincent

Cancer Lett· November 2024

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Transcriptome-wide Mendelian randomization during CD4 T cell activation reveals immune-related drug targets for cardiometabolic diseases.
Xueyan Wu, Hui Ying, Qianqian Yang, Qian Yang, Haoyu Liu, Emma E Vincent

Nat Commun· October 2024

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Tuning the electronic structure of gold cluster-assembled materials by altering organophosphine ligands.
Celina Sikorska, Emma Vincent, Andreas Schnepf, Nicola Gaston

Phys Chem Chem Phys· April 2024

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Loss of mitochondrial pyruvate carrier 1 supports proline-dependent proliferation and collagen biosynthesis in ovarian cancer.
M Rufaik Farook, Zack Croxford, Steffan Morgan, Anthony D Horlock, Amy K Holt, Emma E Vincent

Mol Metab· March 2024

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A genome-wide association study of neutrophil count in individuals associated to an African continental ancestry group facilitates studies of malaria pathogenesis.
Andrei-Emil Constantinescu, David A Hughes, Caroline J Bull, Kathryn Fleming, Ruth E Mitchell, Emma E Vincent

Hum Genomics· March 2024

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Impact of weight loss on cancer-related proteins in serum: results from a cluster randomised controlled trial of individuals with type 2 diabetes.
Caroline J Bull, Emma Hazelwood, Danny N Legge, Laura J Corbin, Tom G Richardson, Emma E Vincent

EBioMedicine· February 2024

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The metabolomic signature of weight loss and remission in the Diabetes Remission Clinical Trial (DiRECT).
Laura J Corbin, David A Hughes, Caroline J Bull, Emma E Vincent, Madeleine L Smith

Diabetologia· January 2024

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Identifying metabolic features of colorectal cancer liability using Mendelian randomization.
Caroline Bull, Emma Hazelwood, Joshua A Bell, Vanessa Tan, Andrei-Emil Constantinescu, Emma E Vincent

Elife· December 2023

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A phenome-wide approach to identify causal risk factors for deep vein thrombosis.
Andrei-Emil Constantinescu, Caroline J Bull, Lucy J Goudswaard, Jie Zheng, Benjamin Elsworth, Emma E Vincent

BMC Med Genomics· November 2023

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Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition.
Amy K Holt, Arafath K Najumudeen, Tracey J Collard, Hao Li, Laura M Millett, Emma E Vincent

Cancer Metab· October 2023

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The tumor multi-omic landscape of endometrial cancers developed on a germline genetic background of adiposity.
George Richenberg, Amy Francis, Carina N Owen, Victoria Gray, Timothy Robinson, Emma E Vincent

medRxiv· October 2023

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