Publications by authors named "Emmanuel Akala"

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Nanotechnology Platform for the Delivery of Docetaxel and Tyrosine Kinase Inhibitors for HER2-Positive Breast Cancer Therapy.
Bharathi Mandala, Yvonne Berko, Gantumur Battogtokh, Funmilola Fisusi, Haijun Gao, Emmanuel O Akala

Pharm Nanotechnol· January 2026

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Multiscale Computational Studies of PEG Chain Length Effects on HER2 mAb Fc Structure and Binding Energetics.
Heather A Noriega, Emmanuel O Akala, Xiang Simon Wang

ACS Omega· December 2025

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Development of Novel Neratinib and Docetaxel Core-Loaded and Trastuzumab Surface-Conjugated Nanoparticle for Treatment of HER-2 Positive Breast Cancer.
Victor Ejigah, Gantumur Battogtokh, Bharathi Mandala, Emmanuel O Akala

Pharmaceutics· September 2025

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Development of Multifunctional Targeted Dual-Loaded Polymeric Nanoparticles for Triple-Negative Breast Cancer Treatment.
Gantumur Battogtokh, Emmanuel O Akala

Pharmaceutics· March 2025

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Recent Developments in Combination Immunotherapy with Other Therapies and Nanoparticle-Based Therapy for Triple-Negative Breast Cancer (TNBC).
Gantumur Battogtokh, Onyinyechi Obidiro, Emmanuel O Akala

Cancers (Basel)· May 2024

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Triple Negative Breast Cancer Treatment Options and Limitations: Future Outlook.
Onyinyechi Obidiro, Gantumur Battogtokh, Emmanuel O Akala

Pharmaceutics· June 2023

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Dispersion polymerization induced self-assembly (pisa) techniques for the fabrication of polymeric nanoparticles for biomedical applications.
Emmanuel O Akala

Nanotechnol Lett· January 2023

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Nanotechnology in the development of small and large molecule tyrosine kinase inhibitors and immunotherapy for the treatment of HER2-positive breast cancer.
Victor Ejigah, Bharathi Mandala, Emmanuel O Akala

J Cancer Metastasis Res· April 2022

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AMPK Signaling Regulates Mitophagy and Mitochondrial ATP Production in Human Trophoblast Cell Line BeWo.
Bin Wu, Yun Chen, Robert Clarke, Emmanuel Akala, Peixin Yang

Front Biosci (Landmark Ed)· April 2022

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A Pre-matriculation Success Program to Improve Pharmacy Students' Academic Performance at a Historically Black University.
Mary K Awuonda, Emmanuel Akala, La'Marcus T Wingate, Salome Bwayo Weaver, Kirsten Brown

Am J Pharm Educ· June 2021

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Computer Optimization of Stealth Biodegradable Polymeric Dual-loaded Nanoparticles for Cancer Therapy Using Central Composite Face-centered Design.
Yvonne A Berko, Emmanuel O Akala

Pharm Nanotechnol· December 2020

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Studies on polyethylene glycol-monoclonal antibody conjugates for fabrication of nanoparticles for biomedical applications.
Funmilola Fisusi, Nailah Brandy, Jingbo Wu, Emmanuel O Akala

J Nanosci Nanomed· July 2020

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Drug Combinations in Breast Cancer Therapy.
Funmilola A Fisusi, Emmanuel O Akala

Pharm Nanotechnol· October 2019

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pH-Sensitive Polymeric Nanoparticles Fabricated by Dispersion Polymerization for the Delivery of Bioactive Agents.
Reema Puri, Solomon A Berhe, Emmanuel O Akala

Pharm Nanotechnol· May 2019

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Cellular uptake and cytotoxicity studies of pH-responsive polymeric nanoparticles fabricated by dispersion polymerization.
Reema Puri, Simeon Adesina, Emmanuel Akala

J Nanosci Nanomed· September 2018

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Antiretroviral Drugs-Loaded Nanoparticles Fabricated by Dispersion Polymerization with Potential for HIV/AIDS Treatment.
Oluwaseun Ogunwuyi, Namita Kumari, Kahli A Smith, Oleg Bolshakov, Simeon Adesina, Emmanuel O Akala

Infect Dis (Auckl)· March 2016

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Activation of HIV-1 with Nanoparticle-Packaged Small-Molecule Protein Phosphatase-1-Targeting Compound.
Kahli A Smith, Xionghao Lin, Oleg Bolshakov, James Griffin, Xiaomei Niu, Emmanuel Akala

Sci Pharm· February 2016

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Nanotechnology Approaches for the Delivery of Exogenous siRNA for HIV Therapy.
Simeon K Adesina, Emmanuel O Akala

Mol Pharm· December 2015

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Computer Optimization of Biodegradable Nanoparticles Fabricated by Dispersion Polymerization.
Emmanuel O Akala, Simeon Adesina, Oluwaseun Ogunwuyi

Int J Environ Res Public Health· December 2015

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Optimization of the fabrication of novel stealth PLA-based nanoparticles by dispersion polymerization using D-optimal mixture design.
Simeon K Adesina, Scott A Wight, Emmanuel O Akala

Drug Dev Ind Pharm· November 2014

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Polylactide-based paclitaxel-loaded nanoparticles fabricated by dispersion polymerization: characterization, evaluation in cancer cell lines, and preliminary biodistribution studies.
Simeon K Adesina, Alesia Holly, Gabriela Kramer-Marek, Jacek Capala, Emmanuel O Akala

J Pharm Sci· August 2014

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MS-Monitored Conjugation of Poly(ethylene glycol) Monomethacrylate to RGD Peptides.
Oleg I Bol'shakov, Emmanuel O Akala

J Appl Polym Sci Symp· July 2014

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Disposition of naltrexone after intravenous bolus administration in Wistar rats, low-alcohol-drinking rats and high-alcohol-drinking rats.
Emmanuel O Akala, Hu Wang, Adedayo Adedoyin

Neuropsychobiology· April 2009

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Organic redox-initiated polymerization process for the fabrication of hydrogels for colon-specific drug delivery.
Emmanuel O Akala, Oluchi Elekwachi, Vantoria Chase, Hausalynn Johnson, Marjorie Lazarre

Drug Dev Ind Pharm· April 2003

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Design of naltrexone-loaded hydrolyzable crosslinked nanoparticles.
Wusheng Yin, Emmanuel O Akala, Robert E Taylor

Int J Pharm· September 2002

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