Publications by authors named "Emmanuel Compe"

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Trichothiodystrophy-causative pathogenic variants impair a cooperative action of TFIIH and DDX1 in R-loop processing.
Debora Ferri, Giulia Branca, Manuela Lanzafame, Erica Gandolfi, Valentina Riva, Emmanuel Compe

Nucleic Acids Res· July 2025

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Pan-inhibition of super-enhancer-driven oncogenic transcription by next-generation synthetic ecteinascidins yields potent anti-cancer activity.
Max Cigrang, Julian Obid, Maguelone Nogaret, Léane Seno, Tao Ye, Emmanuel Compe

Nat Commun· January 2025

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Transcription: friend or foe of genome stability.
Emmanuel Compe, Donata Orioli

FEBS Lett· January 2025

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Super-enhancer-driven expression of BAHCC1 promotes melanoma cell proliferation and genome stability.
Pietro Berico, Maguelone Nogaret, Max Cigrang, Antonin Lallement, Fatemeh Vand-Rajabpour, Emmanuel Compe

Cell Rep· November 2023

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Active mRNA degradation by EXD2 nuclease elicits recovery of transcription after genotoxic stress.
Jérémy Sandoz, Max Cigrang, Amélie Zachayus, Philippe Catez, Lise-Marie Donnio, Emmanuel Compe

Nat Commun· January 2023

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Phosphorylation of XPD drives its mitotic role independently of its DNA repair and transcription functions.
Emmanuel Compe, Evanthia Pangou, Nicolas Le May, Clémence Elly, Cathy Braun

Sci Adv· August 2022

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Promoters of ASCL1- and NEUROD1-dependent genes are specific targets of lurbinectedin in SCLC cells.
Federico Costanzo, Marta Martínez Diez, Gema Santamaría Nuñez, Juan Ignacio Díaz-Hernandéz, Carlos Mario Genes Robles, Emmanuel Compe

EMBO Mol Med· April 2022

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HR-Bac, a toolbox based on homologous recombination for expression, screening and production of multiprotein complexes using the baculovirus expression system.
Olga Kolesnikova, Amélie Zachayus, Simon Pichard, Judit Osz, Natacha Rochel, Emmanuel Compe

Sci Rep· February 2022

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Author Correction: HR-Bac, a toolbox based on homologous recombination for expression, screening and production of multiprotein complexes using the baculovirus expression system.
Olga Kolesnikova, Amélie Zachayus, Simon Pichard, Judit Osz, Natacha Rochel, Emmanuel Compe

Sci Rep· February 2022

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CDK7 and MITF repress a transcription program involved in survival and drug tolerance in melanoma.
Pietro Berico, Max Cigrang, Guillaume Davidson, Cathy Braun, Jeremy Sandoz, Emmanuel Compe

EMBO Rep· September 2021

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The Long Road to Understanding RNAPII Transcription Initiation and Related Syndromes.
Emmanuel Compe, Jean-Marc Egly

Annu Rev Biochem· June 2021

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Reduced levels of prostaglandin I synthase: a distinctive feature of the cancer-free trichothiodystrophy.
Anita Lombardi, Lavinia Arseni, Roberta Carriero, Emmanuel Compe, Elena Botta

Proc Natl Acad Sci U S A· June 2021

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A PKD-MFF signaling axis couples mitochondrial fission to mitotic progression.
Evanthia Pangou, Olga Bielska, Lucile Guerber, Stephane Schmucker, Arantxa Agote-Arán, Emmanuel Compe

Cell Rep· May 2021

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Dysregulation of LXR responsive genes contribute to ichthyosis in trichothiodystrophy.
Satoru Hashimoto, Hiroki Takanari, Emmanuel Compe, Jean-Marc Egly

J Dermatol Sci· March 2020

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TFIIE orchestrates the recruitment of the TFIIH kinase module at promoter before release during transcription.
Emmanuel Compe, Carlos M Genes, Cathy Braun, Frederic Coin, Jean-Marc Egly

Nat Commun· May 2019

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Lurbinectedin Specifically Triggers the Degradation of Phosphorylated RNA Polymerase II and the Formation of DNA Breaks in Cancer Cells.
Gema Santamaría Nuñez, Carlos Mario Genes Robles, Christophe Giraudon, Juan Fernando Martínez-Leal, Emmanuel Compe

Mol Cancer Ther· October 2016

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Nucleotide Excision Repair and Transcriptional Regulation: TFIIH and Beyond.
Emmanuel Compe, Jean-Marc Egly

Annu Rev Biochem· June 2016

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TFIIH-dependent MMP-1 overexpression in trichothiodystrophy leads to extracellular matrix alterations in patient skin.
Lavinia Arseni, Manuela Lanzafame, Emmanuel Compe, Paola Fortugno, António Afonso-Barroso

Proc Natl Acad Sci U S A· February 2015

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Dynamic partnership between TFIIH, PGC-1α and SIRT1 is impaired in trichothiodystrophy.
Hussein Traboulsi, Serena Davoli, Philippe Catez, Jean-Marc Egly, Emmanuel Compe

PLoS Genet· October 2014

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Abnormal XPD-induced nuclear receptor transactivation in DNA repair disorders: trichothiodystrophy and xeroderma pigmentosum.
Xiaolong Zhou, Sikandar G Khan, Deborah Tamura, Takahiro Ueda, Jennifer Boyle, Emmanuel Compe

Eur J Hum Genet· August 2013

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XPD mutations in trichothiodystrophy hamper collagen VI expression and reveal a role of TFIIH in transcription derepression.
Donata Orioli, Emmanuel Compe, Tiziana Nardo, Manuela Mura, Christophe Giraudon

Hum Mol Genet· March 2013

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TFIIH: when transcription met DNA repair.
Emmanuel Compe, Jean-Marc Egly

Nat Rev Mol Cell Biol· May 2012

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The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process.
Pierre Chymkowitch, Nicolas Le May, Pierre Charneau, Emmanuel Compe, Jean-Marc Egly

EMBO J· February 2011

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Both XPD alleles contribute to the phenotype of compound heterozygote xeroderma pigmentosum patients.
Takahiro Ueda, Emmanuel Compe, Philippe Catez, Kenneth H Kraemer, Jean-Marc Egly

J Exp Med· December 2009

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[Neurological disorders and trichothiodystrophy: when the transcription process is impaired].
Emmanuel Compe, Jean-Marc Egly

Med Sci (Paris)· December 2007

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