Publications by authors named "Emmanuel Heilmann"

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The cryo-EM structure of Photosystem I from Chromera velia with a bound superoxide dismutase heterodimer.
Xukun Yuan, Martin Lukeš, Pu Qian, Quentin Charras, Tomáš Smrčka, Emmanuel Heilmann

Nat Commun· December 2025

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Using Vesicular Stomatitis Virus as a Platform for Directed Protease Evolution.
Francesco Costacurta, Stefanie Rauch, Dorothee von Laer, Emmanuel Heilmann

Curr Protoc· December 2024

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Highly specific SARS-CoV-2 main protease (M) mutations against the clinical antiviral ensitrelvir selected in a safe, VSV-based system.
Stefanie Rauch, Francesco Costacurta, Helge Schöppe, Ju-Yi Peng, David Bante, Emmanuel Heilmann

Antiviral Res· November 2024

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Vesicular Stomatitis Virus as a Platform for Protease Activity Measurements.
Stefanie Rauch, Francesco Costacurta, Dorothee von Laer, Emmanuel Heilmann

Curr Protoc· November 2024

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A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system.
Francesco Costacurta, Andrea Dodaro, David Bante, Helge Schöppe, Ju-Yi Peng, Emmanuel Heilmann

PLoS Pathog· September 2024

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Study of key residues in MERS-CoV and SARS-CoV-2 main proteases for resistance against clinically applied inhibitors nirmatrelvir and ensitrelvir.
Laura Krismer, Helge Schöppe, Stefanie Rauch, David Bante, Bernhard Sprenger, Emmanuel Heilmann

Npj Viruses· June 2024

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A comprehensive study of SARS-CoV-2 main protease (M) inhibitor-resistant mutants selected in a VSV-based system.
Francesco Costacurta, Andrea Dodaro, David Bante, Helge Schöppe, Bernhard Sprenger, Emmanuel Heilmann

bioRxiv· October 2023

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Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors.
Seyed Arad Moghadasi, Emmanuel Heilmann, Ahmed Magdy Khalil, Christina Nnabuife, Fiona L Kearns

Sci Adv· March 2023

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SARS-CoV-2 3CL mutations selected in a VSV-based system confer resistance to nirmatrelvir, ensitrelvir, and GC376.
Emmanuel Heilmann, Francesco Costacurta, Seyed Arad Moghadasi, Chengjin Ye, Matteo Pavan

Sci Transl Med· January 2023

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Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors.
Seyed Arad Moghadasi, Emmanuel Heilmann, Ahmed Magdy Khalil, Christina Nnabuife, Fiona L Kearns

bioRxiv· December 2022

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A VSV-based assay quantifies coronavirus Mpro/3CLpro/Nsp5 main protease activity and chemical inhibition.
Emmanuel Heilmann, Francesco Costacurta, Stephan Geley, Seyad Arad Mogadashi, Andre Volland

Commun Biol· April 2022

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Heparan sulfate proteoglycans serve as alternative receptors for low affinity LCMV variants.
André Volland, Michael Lohmüller, Emmanuel Heilmann, Janine Kimpel, Sebastian Herzog

PLoS Pathog· October 2021

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The Methyltransferase Region of Vesicular Stomatitis Virus L Polymerase Is a Target Site for Functional Intramolecular Insertion.
Emmanuel Heilmann, Janine Kimpel, Stephan Geley, Andreas Naschberger, Carles Urbiola

Viruses· October 2019

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