Publications by authors named "Emmanuel J Botzolakis"

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Brain MRI Deep Learning and Bayesian Inference System Augments Radiology Resident Performance.
Jeffrey D Rudie, Jeffrey Duda, Michael Tran Duong, Po-Hao Chen, Long Xie, Emmanuel J Botzolakis

J Digit Imaging· August 2021

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Subspecialty-Level Deep Gray Matter Differential Diagnoses with Deep Learning and Bayesian Networks on Clinical Brain MRI: A Pilot Study.
Jeffrey D Rudie, Andreas M Rauschecker, Long Xie, Jiancong Wang, Michael Tran Duong, Emmanuel J Botzolakis

Radiol Artif Intell· September 2020

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Artificial Intelligence System Approaching Neuroradiologist-level Differential Diagnosis Accuracy at Brain MRI.
Andreas M Rauschecker, Jeffrey D Rudie, Long Xie, Jiancong Wang, Michael Tran Duong, Emmanuel J Botzolakis

Radiology· June 2020

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Comparison of γ-Aminobutyric Acid, Type A (GABAA), Receptor αβγ and αβδ Expression Using Flow Cytometry and Electrophysiology: EVIDENCE FOR ALTERNATIVE SUBUNIT STOICHIOMETRIES AND ARRANGEMENTS.
Emmanuel J Botzolakis, Katharine N Gurba, Andre H Lagrange, Hua-Jun Feng, Aleksandar K Stanic

J Biol Chem· September 2016

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GABAA receptor biogenesis is impaired by the γ2 subunit febrile seizure-associated mutation, GABRG2(R177G).
Emily Todd, Katharine N Gurba, Emmanuel J Botzolakis, Aleksandar K Stanic, Robert L Macdonald

Neurobiol Dis· September 2014

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Relation of melatonin to sleep architecture in children with autism.
Roberta M Leu, Liya Beyderman, Emmanuel J Botzolakis, Kyla Surdyka, Lily Wang

J Autism Dev Disord· April 2011

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The effect of HSP-causing mutations in SPG3A and NIPA1 on the assembly, trafficking, and interaction between atlastin-1 and NIPA1.
Emmanuel J Botzolakis, Jiali Zhao, Katharine N Gurba, Robert L Macdonald, Peter Hedera

Mol Cell Neurosci· January 2011

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Targeting ligand-gated ion channels in neurology and psychiatry: is pharmacological promiscuity an obstacle or an opportunity?
Matt T Bianchi, Emmanuel J Botzolakis

BMC Pharmacol· March 2010

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Benzodiazepine modulation of GABA(A) receptor opening frequency depends on activation context: a patch clamp and simulation study.
Matt T Bianchi, Emmanuel J Botzolakis, Andre H Lagrange, Robert L Macdonald

Epilepsy Res· August 2009

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Context-dependent modulation of alphabetagamma and alphabetadelta GABA A receptors by penicillin: implications for phasic and tonic inhibition.
Hua-Jun Feng, Emmanuel J Botzolakis, Robert L Macdonald

Neuropharmacology· January 2009

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Hereditary spastic paraplegia-associated mutations in the NIPA1 gene and its Caenorhabditis elegans homolog trigger neural degeneration in vitro and in vivo through a gain-of-function mechanism.
Jiali Zhao, Dawn S Matthies, Emmanuel J Botzolakis, Robert L Macdonald, Randy D Blakely

J Neurosci· December 2008

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A conserved Cys-loop receptor aspartate residue in the M3-M4 cytoplasmic loop is required for GABAA receptor assembly.
Wen-yi Lo, Emmanuel J Botzolakis, Xin Tang, Robert L Macdonald

J Biol Chem· October 2008

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Microscopic kinetic determinants of macroscopic currents: insights from coupling and uncoupling of GABAA receptor desensitization and deactivation.
Matt T Bianchi, Emmanuel J Botzolakis, Kevin F Haas, Janet L Fisher, Robert L Macdonald

J Physiol· November 2007

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Enhanced macroscopic desensitization shapes the response of alpha4 subtype-containing GABAA receptors to synaptic and extrasynaptic GABA.
Andre H Lagrange, Emmanuel J Botzolakis, Robert L Macdonald

J Physiol· February 2007

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