Publications by authors named "Emmanuel Merigeon"

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Complement component C1q is an immunological rheostat that regulates Fc:FcR interactions.
Edward C So, Hua Zhou, Ariana Greenwell, Erin E Burch, Yaping Ji

Immunogenetics· August 2023

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Fc multimers effectively treat murine models of multiple sclerosis.
Jin Wang, Kellie Brown, Caroline Danehy, Emmanuel Mérigeon, Stephen Goralski

Front Immunol· August 2023

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An ACE2-IgG4 Fc Fusion Protein Demonstrates Strong Binding to All Tested SARS-CoV-2 Variants and Reduced Lung Inflammation in Animal Models of SARS-CoV-2 and Influenza.
Emmanuel Y Merigeon, Dong Yang, Elizabeth A Ihms, Leda C Bassit, Elizabeth A Fitzpatrick

Pathog Immun· August 2022

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A recombinant human IgG1 Fc multimer designed to mimic the active fraction of IVIG in autoimmunity.
Xiaoyu Zhang, Jane Owens, Henrik S Olsen, Edward So, Erin Burch

JCI Insight· January 2019

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Recombinant human IgG1 based Fc multimers, with limited FcR binding capacity, can effectively inhibit complement-mediated disease.
Haoping Sun, Henrik S Olsen, Emmanuel Y Mérigeon, Edward So, Erin Burch

J Autoimmun· November 2017

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A fully recombinant human IgG1 Fc multimer (GL-2045) inhibits complement-mediated cytotoxicity and induces iC3b.
Hua Zhou, Henrik Olsen, Edward So, Emmanuel Mérigeon, Denis Rybin

Blood Adv· March 2017

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Anti-CD20 Antibody with Multimerized Fc Domains: A Novel Strategy To Deplete B Cells and Augment Treatment of Autoimmune Disease.
Xiaoyu Zhang, Henrik S Olsen, Shaodong Chen, Edward So, Hua Zhou

J Immunol· February 2016

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Tumour antigen targeted monoclonal antibodies incorporating a novel multimerisation domain significantly enhance antibody dependent cellular cytotoxicity against colon cancer.
Ajay Jain, Bhawna Poonia, Edward C So, Ravi Vyzasatya, Erin E Burch

Eur J Cancer· October 2013

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Fully recombinant IgG2a Fc multimers (stradomers) effectively treat collagen-induced arthritis and prevent idiopathic thrombocytopenic purpura in mice.
Ajay Jain, Henrik S Olsen, Ravi Vyzasatya, Erin Burch, Yukimi Sakoda

Arthritis Res Ther· August 2012

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Assay for measurement of intact B-type natriuretic peptide prohormone in blood.
Isabelle Giuliani, François Rieunier, Catherine Larue, Jean-François Delagneau, Claude Granier, Emmanuel Merigeon

Clin Chem· June 2006

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