Publications by authors named "Emmanuel Vial"

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Impact of Minor Structural Modifications on Properties of a Series of mTOR Inhibitors.
Gilles Ouvry, Laurence Clary, Loïc Tomas, Michèle Aurelly, Laetitia Bonnary, Emmanuel Vial

ACS Med Chem Lett· November 2019

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A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils.
Baptiste Janela, Amit A Patel, Mai Chan Lau, Chi Ching Goh, Rasha Msallam, Emmanuel Vial

Immunity· April 2019

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Brimonidine displays anti-inflammatory properties in the skin through the modulation of the vascular barrier function.
Béatrice Bertino, Sandrine Blanchet-Réthoré, Séverine Thibaut de Ménonville, Philippe Reynier, Bruno Méhul, Emmanuel Vial

Exp Dermatol· December 2018

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Sulfoximines as potent RORγ inverse agonists.
Gilles Ouvry, Franck Bihl, Claire Bouix-Peter, Olivier Christin, Claire Defoin-Platel, Emmanuel Vial

Bioorg Med Chem Lett· May 2018

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Discovery and process development of a novel TACE inhibitor for the topical treatment of psoriasis.
Jean-Guy Boiteau, Gilles Ouvry, Jean-Marie Arlabosse, Stéphanie Astri, Audrey Beillard, Emmanuel Vial

Bioorg Med Chem· February 2018

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Discovery and Characterization of CD12681, a Potent RORγ Inverse Agonist, Preclinical Candidate for the Topical Treatment of Psoriasis.
Gilles Ouvry, Nicolas Atrux-Tallau, Franck Bihl, Aline Bondu, Claire Bouix-Peter, Emmanuel Vial

ChemMedChem· February 2018

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Protective Effect of Dermal Brimonidine Applications Against UV Radiation-induced Skin Tumors, Epidermal Hyperplasia and Cell Proliferation in the Skin of Hairless Mice.
Guy Bouvier, Douglas B Learn, Christelle Nonne, Gérard Feraille, Emmanuel Vial

Photochem Photobiol· November 2015

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Combining two repurposed drugs as a promising approach for Alzheimer's disease therapy.
Ilya Chumakov, Serguei Nabirotchkin, Nathalie Cholet, Aude Milet, Aurélie Boucard, Emmanuel Vial

Sci Rep· January 2015

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Polytherapy with a combination of three repurposed drugs (PXT3003) down-regulates Pmp22 over-expression and improves myelination, axonal and functional parameters in models of CMT1A neuropathy.
Ilya Chumakov, Aude Milet, Nathalie Cholet, Gwenaël Primas, Aurélie Boucard, Emmanuel Vial

Orphanet J Rare Dis· December 2014

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Major contribution of MEK1 to the activation of ERK1/ERK2 and to the growth of LS174T colon carcinoma cells.
Jessica Shama, Raquel Garcia-Medina, Jacques Pouysségur, Emmanuel Vial

Biochem Biophys Res Commun· August 2008

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Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility.
Erik Sahai, Raquel Garcia-Medina, Jacques Pouysségur, Emmanuel Vial

J Cell Biol· January 2007

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Elevated ERK-MAP kinase activity protects the FOS family member FRA-1 against proteasomal degradation in colon carcinoma cells.
Emmanuel Vial, Christopher J Marshall

J Cell Sci· December 2003

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ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility.
Emmanuel Vial, Erik Sahai, Christopher J Marshall

Cancer Cell· July 2003

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v-Jun downregulates the SPARC target gene by binding to the proximal promoter indirectly through Sp1/3.
Sandrine Chamboredon, Joseph Briggs, Emmanuel Vial, Julien Hurault, Federico Galvagni

Oncogene· June 2003

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