Publications by authors named "Emmanuel Zazopoulos"

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Comparative characterization of the lactimidomycin and iso-migrastatin biosynthetic machineries revealing unusual features for acyltransferase-less type I polyketide synthases and providing an opportunity to engineer new analogues.
Jeong-Woo Seo, Ming Ma, Thomas Kwong, Jianhua Ju, Si-Kyu Lim, Emmanuel Zazopoulos

Biochemistry· December 2014

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TLN-05220, TLN-05223, new Echinosporamicin-type antibiotics, and proposed revision of the structure of bravomicins(*).
Arjun H Banskota, Mustapha Aouidate, Dan Sørensen, Ashraf Ibrahim, Mahmood Piraee, Emmanuel Zazopoulos

J Antibiot (Tokyo)· October 2009

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iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.
Si-Kyu Lim, Jianhua Ju, Emmanuel Zazopoulos, Hui Jiang, Jeong-Woo Seo

J Biol Chem· October 2009

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Biosynthesis of diazepinomicin/ECO-4601, a Micromonospora secondary metabolite with a novel ring system.
James B McAlpine, Arjun H Banskota, Romila D Charan, Gerhard Schlingmann, Emmanuel Zazopoulos

J Nat Prod· September 2008

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Reassembly of anthramycin biosynthetic gene cluster by using recombinogenic cassettes.
Yunfeng Hu, Vanessa V Phelan, Chris M Farnet, Emmanuel Zazopoulos, Brian O Bachmann

Chembiochem· July 2008

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Molecular basis for chloronium-mediated meroterpene cyclization: cloning, sequencing, and heterologous expression of the napyradiomycin biosynthetic gene cluster.
Jaclyn M Winter, Michelle C Moffitt, Emmanuel Zazopoulos, James B McAlpine, Pieter C Dorrestein

J Biol Chem· June 2007

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Benzodiazepine biosynthesis in Streptomyces refuineus.
Yunfeng Hu, Vanessa Phelan, Ioanna Ntai, Chris M Farnet, Emmanuel Zazopoulos

Chem Biol· June 2007

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Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.
Arjun H Banskota, James B Mcalpine, Dan Sørensen, Ashraf Ibrahim, Mustapha Aouidate, Emmanuel Zazopoulos

J Antibiot (Tokyo)· September 2006

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Isolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach.
Arjun H Banskota, James B Mcalpine, Dan Sørensen, Mustapha Aouidate, Mahmood Piraee, Emmanuel Zazopoulos

J Antibiot (Tokyo)· March 2006

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Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.
James B McAlpine, Brian O Bachmann, Mahmood Piraee, Steve Tremblay, Anne-Marie Alarco, Emmanuel Zazopoulos

J Nat Prod· April 2005

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The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases.
Wen Liu, Koichi Nonaka, Liping Nie, Jian Zhang, Steven D Christenson, Emmanuel Zazopoulos

Chem Biol· March 2005

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A genomics-guided approach for discovering and expressing cryptic metabolic pathways.
Emmanuel Zazopoulos, Kexue Huang, Alfredo Staffa, Wen Liu, Brian O Bachmann

Nat Biotechnol· February 2003

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The calicheamicin gene cluster and its iterative type I enediyne PKS.
Joachim Ahlert, Erica Shepard, Natalia Lomovskaya, Emmanuel Zazopoulos, Alfredo Staffa

Science· August 2002

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