Publications by authors named "Emmanuelle Proust"

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Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: design, synthesis and structure-activity relationship studies.
Fabrice Vergne, Patrick Bernardelli, Edwige Lorthiois, Nga Pham, Emmanuelle Proust

Bioorg Med Chem Lett· September 2004

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Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 2: metabolism-directed optimization studies towards orally bioavailable derivatives.
Fabrice Vergne, Patrick Bernardelli, Edwige Lorthiois, Nga Pham, Emmanuelle Proust

Bioorg Med Chem Lett· September 2004

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Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 1.
Edwige Lorthiois, Patrick Bernardelli, Fabrice Vergne, Chrystelle Oliveira, Abdel-Kader Mafroud, Emmanuelle Proust

Bioorg Med Chem Lett· September 2004

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Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 2: Optimization of 5,8-disubstituted derivatives.
Patrick Bernardelli, Edwige Lorthiois, Fabrice Vergne, Chrystelle Oliveira, Abdel-Kader Mafroud, Emmanuelle Proust

Bioorg Med Chem Lett· September 2004

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