Publications by authors named "Emmy W Verschuren"

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ScType enables fast and accurate cell type identification from spatial transcriptomics data.
Kristen Nader, Misra Tasci, Aleksandr Ianevski, Andrew Erickson, Emmy W Verschuren

Bioinformatics· July 2024

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A community challenge to predict clinical outcomes after immune checkpoint blockade in non-small cell lung cancer.
Mike Mason, Óscar Lapuente-Santana, Anni S Halkola, Wenyu Wang, Raghvendra Mall, Emmy W Verschuren

J Transl Med· February 2024

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Effective intravenous delivery of adenovirus armed with TNFα and IL-2 improves anti-PD-1 checkpoint blockade in non-small cell lung cancer.
Tatiana V Kudling, James H A Clubb, Santeri Pakola, Dafne C A Quixabeira, Iris A K Lähdeniemi, Emmy W Verschuren

Oncoimmunology· August 2023

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PI3Kβ inhibition enhances ALK-inhibitor sensitivity in ALK-rearranged lung cancer.
Sarang S Talwelkar, Mikko I Mäyränpää, Julia Schüler, Nora Linnavirta, Annabrita Hemmes, Emmy W Verschuren

Mol Oncol· May 2023

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Protocol to utilize fresh uncultured human lung tumor cells for personalized functional diagnostics.
Sarang S Talwelkar, Iris A K Lähdeniemi, Mikko I Mäyränpää, Annabrita Hemmes, Nora Linnavirta, Emmy W Verschuren

STAR Protoc· December 2022

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Development of an adenosquamous carcinoma histopathology - selective lung metastasis model.
Iris A K Lähdeniemi, Jennifer R Devlin, Ashwini S Nagaraj, Sarang S Talwelkar, Jie Bao, Emmy W Verschuren

Biol Open· December 2022

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Inactivation of AMPK Leads to Attenuation of Antigen Presentation and Immune Evasion in Lung Adenocarcinoma.
Yajing Gao, Pekka Päivinen, Sushil Tripathi, Eva Domènech-Moreno, Iris P L Wong, Emmy W Verschuren

Clin Cancer Res· January 2022

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SOX9 has distinct roles in the formation and progression of different non-small cell lung cancer histotypes.
Jie Bao, Katja Närhi, Ana Teodòsio, Annabrita Hemmes, Nora M Linnavirta, Emmy W Verschuren

J Pathol· September 2021

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Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments.
Sarang S Talwelkar, Mikko I Mäyränpää, Lars Søraas, Swapnil Potdar, Jie Bao, Emmy W Verschuren

Cell Rep Med· August 2021

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Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin.
Topi A Tervonen, Shishir M Pant, Denis Belitškin, Johanna I Englund, Katja Närhi, Emmy W Verschuren

Cancer Res· March 2021

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Spa-RQ: an Image Analysis Tool to Visualise and Quantify Spatial Phenotypes Applied to Non-Small Cell Lung Cancer.
Jie Bao, Margarita Walliander, Ferenc Kovács, Ashwini S Nagaraj, Annabrita Hemmes, Emmy W Verschuren

Sci Rep· November 2019

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Receptor Tyrosine Kinase Signaling Networks Define Sensitivity to ERBB Inhibition and Stratify -Mutant Lung Cancers.
Sarang S Talwelkar, Ashwini S Nagaraj, Jennifer R Devlin, Annabrita Hemmes, Swapnil Potdar, Emmy W Verschuren

Mol Cancer Ther· October 2019

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Establishment and Analysis of Tumor Slice Explants As a Prerequisite for Diagnostic Testing.
Ashwini S Nagaraj, Jie Bao, Annabrita Hemmes, Mafalda Machado, Katja Närhi, Emmy W Verschuren

J Vis Exp· November 2018

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More than a Tumor Suppressor: E-Cadherin Loss Drives Lung Cancer Metastasis.
Jennifer R Devlin, Emmy W Verschuren

Am J Respir Cell Mol Biol· August 2018

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Spatial aspects of oncogenic signalling determine the response to combination therapy in slice explants from Kras-driven lung tumours.
Katja Närhi, Ashwini S Nagaraj, Elina Parri, Riku Turkki, Petra W van Duijn, Emmy W Verschuren

J Pathol· May 2018

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Protocols and characterization data for 2D, 3D, and slice-based tumor models from the PREDECT project.
Ronald de Hoogt, Marta F Estrada, Suzana Vidic, Emma J Davies, Annika Osswald, Emmy W Verschuren

Sci Data· November 2017

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Cell of Origin Links Histotype Spectrum to Immune Microenvironment Diversity in Non-small-Cell Lung Cancer Driven by Mutant Kras and Loss of Lkb1.
Ashwini S Nagaraj, Jenni Lahtela, Annabrita Hemmes, Teijo Pellinen, Sami Blom, Emmy W Verschuren

Cell Rep· January 2017

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Capturing complex tumour biology in vitro: histological and molecular characterisation of precision cut slices.
Emma J Davies, Meng Dong, Matthias Gutekunst, Katja Närhi, Hanneke J A A van Zoggel, Emmy W Verschuren

Sci Rep· December 2015

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KSHV viral cyclin interferes with T-cell development and induces lymphoma through Cdk6 and Notch activation in vivo.
Pirita Pekkonen, Annika Järviluoma, Nadezhda Zinovkina, Anna Cvrljevic, Sonam Prakash, Emmy W Verschuren

Cell Cycle· September 2015

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The putative tumor suppressor gene EphA3 fails to demonstrate a crucial role in murine lung tumorigenesis or morphogenesis.
Jenni Lahtela, Barun Pradhan, Katja Närhi, Annabrita Hemmes, Merja Särkioja, Emmy W Verschuren

Dis Model Mech· April 2015

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Extendable blocking probe in reverse transcription for analysis of RNA variants with superior selectivity.
Tho H Ho, Kien X Dang, Susanna Lintula, Kristina Hotakainen, Lin Feng, Emmy W Verschuren

Nucleic Acids Res· January 2015

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A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3.
Jenni Lahtela, Laura B Corson, Annabrita Hemmes, Matthew J Brauer, Sonja Koopal, Emmy W Verschuren

Cell Cycle· February 2013

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APC/C(Cdc20) targets E2F1 for degradation in prometaphase.
Melissa J Peart, Masha V Poyurovsky, Elizabeth M Kass, Marshall Urist, Emmy W Verschuren

Cell Cycle· October 2010

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Loss of Emi1-dependent anaphase-promoting complex/cyclosome inhibition deregulates E2F target expression and elicits DNA damage-induced senescence.
Emmy W Verschuren, Kenneth H Ban, Marilyn A Masek, Norman L Lehman, Peter K Jackson

Mol Cell Biol· November 2007

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Putting transcription repression and protein destruction in pRb's pocket.
Emmy W Verschuren, Peter K Jackson

Dev Cell· February 2007

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