Publications by authors named "Eng-Hui Chew"

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An In-House Developed Probiotics Database E-Reference Information for Healthcare Professionals.
Adison Goh, Brigitta Budijono, Christine Lim, Eng Hui Chew, Kevin Yap

Stud Health Technol Inform· January 2024

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Elucidating the role of a positive family history in differentiating between axial and peripheral spondyloarthritis: an ancillary analysis of the ASAS-PerSpA study.
Yu Heng Kwan, Luanne Tan, Chuen Seng Tan, Clementina López-Medina, Maxime Dougados, Eng Hui Chew

Clin Exp Rheumatol· September 2022

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Ribisins and Certain Analogues Exert Neuroprotective Effects through Activation of the Keap1-Nrf2-ARE Pathway.
Shen H Tan, Muthukumar Karuppasamy, Ping Lan, Yaochun Zhang, Jiayi Hu, Eng-Hui Chew

ChemMedChem· September 2022

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Development of a Probiotics Practice E-Reference Database for Health Care Professionals.
Adison Dai Yong Goh, Charmaine Sum May Ng, Yhim Ghee Toh, Joy Boon Ka Chong, Eng-Hui Chew

Clin Ther· December 2021

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Development of an Item Bank to Measure Medication Adherence: Systematic Review.
Yu Heng Kwan, Livia Jia Yi Oo, Dionne Hui Fang Loh, Jie Kie Phang, Si Dun Weng, Eng Hui Chew

J Med Internet Res· October 2020

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Validity and reliability of the Assessment of Spondyloarthritis International Society Health Index in English-speaking patients with axial spondyloarthritis in Singapore.
Yu Heng Kwan, Fang Fang Aw, Warren Fong, Jie Kie Phang, Uta Kiltz, Eng Hui Chew

Int J Rheum Dis· September 2019

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A systematic review of the association of obesity with the outcomes of inflammatory rheumatic diseases.
Yi Xuan Lee, Yu Heng Kwan, Ka Keat Lim, Chuen Seng Tan, Nai Lee Lui, Eng Hui Chew

Singapore Med J· June 2019

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A systematic review of the factors associated with the initiation of biologicals in patients with rheumatological conditions.
Wan Yu Png, Yu Heng Kwan, Ka Keat Lim, Eng Hui Chew, Nai Lee Lui

Eur J Hosp Pharm· May 2019

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Factors Associated With Initiation of Biologics in Patients With Axial Spondyloarthritis in an Urban Asian City: A PRESPOND Study.
Wan Yu Png, Yu Heng Kwan, Yi Xuan Lee, Ka Keat Lim, Eng Hui Chew

J Clin Rheumatol· March 2019

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Validity and reliability of the ten-item Connor-Davidson Resilience Scale (CD-RISC10) instrument in patients with axial spondyloarthritis (axSpA) in Singapore.
Yu Heng Kwan, Amanda Ng, Ka Keat Lim, Warren Fong, Jie Kie Phang, Eng Hui Chew

Rheumatol Int· January 2019

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Measurement properties of patient reported outcome measures for spondyloarthritis: A systematic review.
Kelly Png, Yu Heng Kwan, Ying Ying Leung, Jie Kie Phang, Jia Qi Lau, Eng Hui Chew

Semin Arthritis Rheum· October 2018

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Novel dual-targeting anti-proliferative dihydrotriazine-chalcone derivatives display suppression of cancer cell invasion and inflammation by inhibiting the NF-κB signaling pathway.
Fei-Fei Gan, Ruirui Zhang, Hui-Li Ng, Muthukumar Karuppasamy, Waygene Seah, Eng-Hui Chew

Food Chem Toxicol· June 2018

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Association of obesity with patient-reported outcomes in patients with axial spondyloarthritis: a cross-sectional study in an urban Asian population.
Yi Xuan Lee, Yu Heng Kwan, Wan Yu Png, Ka Keat Lim, Chuen Seng Tan, Eng Hui Chew

Clin Rheumatol· October 2017

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Design, Synthesis, and Biological Evaluation of Coupled Bioactive Scaffolds as Potential Anticancer Agents for Dual Targeting of Dihydrofolate Reductase and Thioredoxin Reductase.
Hui-Li Ng, Xiang Ma, Eng-Hui Chew, Wai-Keung Chui

J Med Chem· March 2017

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Applying the designed multiple ligands approach to inhibit dihydrofolate reductase and thioredoxin reductase for anti-proliferative activity.
Hui-Li Ng, Shangying Chen, Eng-Hui Chew, Wai-Keung Chui

Eur J Med Chem· June 2016

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Indolin-2-one compounds targeting thioredoxin reductase as potential anticancer drug leads.
Kamila K Kaminska, Helene C Bertrand, Hisashi Tajima, William C Stafford, Qing Cheng, Eng-Hui Chew

Oncotarget· June 2016

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Thioredoxin-dependent regulation of AIF-mediated DNA damage.
Sandeep B Shelar, Kamila K Kaminska, Shridhivya A Reddy, Dilip Kumar, Chong-Teik Tan, Eng-Hui Chew

Free Radic Biol Med· October 2015

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Sulforaphane and its methylcarbonyl analogs inhibit the LPS-stimulated inflammatory response in human monocytes through modulating cytokine production, suppressing chemotactic migration and phagocytosis in a NF-κB- and MAPK-dependent manner.
Shridhivya A Reddy, Sandeep B Shelar, Truong-Minh Dang, Baxter Neng-Cun Lee, Hong Yang, Eng-Hui Chew

Int Immunopharmacol· February 2015

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3-(2-oxoethylidene)indolin-2-one derivatives activate Nrf2 and inhibit NF-κB: potential candidates for chemoprevention.
Amrita A Nagle, Shridhivya A Reddy, Helene Bertrand, Hisashi Tajima, Truong-Minh Dang, Eng-Hui Chew

ChemMedChem· August 2014

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A novel shogaol analog suppresses cancer cell invasion and inflammation, and displays cytoprotective effects through modulation of NF-κB and Nrf2-Keap1 signaling pathways.
Fei-Fei Gan, Hui Ling, Xiaohui Ang, Shridhivya A Reddy, Stephanie S-H Lee, Eng-Hui Chew

Toxicol Appl Pharmacol· November 2013

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Identification of Michael acceptor-centric pharmacophores with substituents that yield strong thioredoxin reductase inhibitory character correlated to antiproliferative activity.
Fei-Fei Gan, Kamila K Kaminska, Hong Yang, Chin-Yee Liew, Pay-Chin Leow, Eng-Hui Chew

Antioxid Redox Signal· October 2013

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Antioxidant and Nrf2 inducing activities of luteolin, a flavonoid constituent in Ixeris sonchifolia Hance, provide neuroprotective effects against ischemia-induced cellular injury.
Yao-Chun Zhang, Fei-Fei Gan, Sandeep Balu Shelar, Ka-Yun Ng, Eng-Hui Chew

Food Chem Toxicol· September 2013

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Studies on the chemical constituents and biological activities of ixeris.
Yao-Chun Zhang, Chun-Nian He, Eng-Hui Chew

Chem Biodivers· August 2013

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Induction of tumor cell death through targeting tubulin and evoking dysregulation of cell cycle regulatory proteins by multifunctional cinnamaldehydes.
Amrita A Nagle, Fei-Fei Gan, Gavin Jones, Choon-Leng So, Geoffrey Wells, Eng-Hui Chew

PLoS One· May 2013

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