Publications by authors named "Eric A Appel"

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Hydrogel formulations for sustained-release of broadly neutralizing antibodies.
Carolyn K Jons, Catherine M Kasse, Bryan T Mayer, Ollivier Hyrien, Samya Sen, Eric A Appel

J Control Release· December 2025

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Enabling global access to potent subunit vaccines with a simple and scalable injectable hydrogel platform.
Priya Ganesh, Alexander N Prossnitz, Carolyn K Jons, Noah Eckman, Alakesh Alakesh, Eric A Appel

Biomater Sci· November 2025

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Cross-Molecular Active Learning for the Discovery of Antimicrobial Polyacrylamides.
Shoshana C Williams, Gabriel Greenstein, Xinyu Liu, Alessio Fragasso, Noah Eckman, Eric A Appel

bioRxiv· November 2025

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Intranasal Sertraline for the Investigation of Nose-to-Brain Delivery to Mitigate Systemic Exposure.
Shoshana C Williams, Travis Lantz, Vanessa Doulames, Alakesh Alakesh, Daniel Ramos Mejia, Eric A Appel

ACS Pharmacol Transl Sci· October 2025

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Osteopontin attenuates the foreign-body response to silicone implants.
Michelle F Griffin, Jennifer B Parker, Ruth Tevlin, Norah E Liang, Caleb Valencia, Eric A Appel

Nat Biomed Eng· August 2025

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Ultrahigh-concentration biologic therapeutics enabled by spray drying with a glassy surfactant excipient.
Carolyn K Jons, Alexander N Prossnitz, Noah Eckman, Changxin Dong, Ashley Utz, Eric A Appel

Sci Transl Med· August 2025

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A Transient Immunostimulatory Niche Synergizes Adoptive and Endogenous Immunity for Enhanced Tumor Control.
Anahita Nejatfard, John H Klich, Noah Eckman, Sophia J Bailey, Kyra Gillard, Eric A Appel

bioRxiv· August 2025

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Hydrogel-to-Aerogel Transitions in Polymer-Particle Hydrogels Expand the Wildfire Defense Window.
Changxin Dong, Samya Sen, Zhennan Ru, Athena Kolli, Paxton S Appel, Eric A Appel

ACS Appl Mater Interfaces· July 2025

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Long-acting hydrogel-based depot formulations of tirzepatide and semaglutide for the management of type 2 diabetes and weight.
Andrea I d'Aquino, Changxin Dong, Leslee T Nguyen, Jerry Yan, Carolyn K Jons, Eric A Appel

bioRxiv· July 2025

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In Vitro Evaluation of Gelatin-Based Hydrogels as Potential Fillers for Corneal Wounds.
Cristina Romo-Valera, Eric A Appel, Jaime Etxebarria, Jon Arluzea, Noelia Andollo

Biomacromolecules· June 2025

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Engineering Sustained-Release Broadly Neutralizing Antibody Formulations.
Carolyn K Jons, Catherine M Kasse, Bryan T Mayer, Ollivier Hyrien, Samya Sen, Eric A Appel

bioRxiv· June 2025

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Sustained Vaccine Exposure Elicits More Rapid, Consistent, and Broad Humoral Immune Responses to Multivalent Influenza Vaccines.
Olivia M Saouaf, Ben S Ou, Ye Eun Song, Joshua J Carter, Jerry Yan, Eric A Appel

Adv Sci (Weinh)· May 2025

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Spatially Tuned Localization of Interleukins and OX40 Agonists Enhances Synergistic Anti-Tumor Immunity.
John H Klich, Anahita Nejatfard, Emily L Meany, Ben S Ou, Julie Baillet, Eric A Appel

bioRxiv· May 2025

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Highly Extensible Physically Crosslinked Hydrogels for High-Speed 3D Bioprinting.
Ye Eun Song, Noah Eckman, Samya Sen, Carolyn K Jons, Olivia M Saouaf, Eric A Appel

Adv Healthc Mater· April 2025

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Sustained exposure to multivalent antigen-decorated nanoparticles generates broad anti-coronavirus responses.
Julie Baillet, John H Klich, Ben S Ou, Emily L Meany, Jerry Yan, Eric A Appel

Matter· April 2025

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Clonally expanded, targetable, natural killer-like NKG7 T cells seed the aged spinal cord to disrupt myeloid-dependent wound healing.
Guiping Kong, Yayue Song, Yuyang Yan, Samantha M Calderazzo, Madhu Sudhana Saddala, Eric A Appel

Neuron· March 2025

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Crosslink strength governs yielding behavior in dynamically crosslinked hydrogels.
Noah Eckman, Abigail K Grosskopf, Grace Jiang, Krutarth Kamani, Michelle S Huang, Eric A Appel

Biomater Sci· March 2025

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Preventing peritendinous adhesions using lubricious supramolecular hydrogels.
Emily L Meany, Christian M Williams, Ye Eun Song, Vanessa M Doulames, Sophia J Bailey, Eric A Appel

bioRxiv· March 2025

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Postoperative adhesions are abrogated by a sustained-release anti-JUN therapeutic in preclinical models.
Deshka S Foster, Jason L Guo, Emily Meany, Charlotte E Berry, Mahsa Fallah, Eric A Appel

Sci Transl Med· March 2025

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Polyacrylamide-Based Antimicrobial Copolymers to Replace or Rescue Antibiotics.
Shoshana C Williams, Madeline B Chosy, Carolyn K Jons, Changxin Dong, Alexander N Prossnitz, Eric A Appel

ACS Cent Sci· March 2025

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Viral Vector Eluting Lenses for Single-Step Targeted Expression of Genetically-Encoded Activity Sensors for in Vivo Microendoscopic Calcium Imaging.
Carolyn K Jons, David Cheng, Changxin Dong, Emily L Meany, Jonathan J Nassi, Eric A Appel

Macromol Biosci· February 2025

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Electrochemically mutable soft metasurfaces.
Siddharth Doshi, Anqi Ji, Ali I Mahdi, Scott T Keene, Skyler P Selvin, Eric A Appel

Nat Mater· February 2025

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Defining Structure-Function Relationships of Amphiphilic Excipients Enables Rational Design of Ultra-Stable Biopharmaceuticals.
Alexander N Prossnitz, Leslee T Nguyen, Noah Eckman, Suraj Borkar, Samantha Tetef, Eric A Appel

Adv Sci (Weinh)· February 2025

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A thiol-ene click-based strategy to customize injectable polymer-nanoparticle hydrogel properties for therapeutic delivery.
Sophia J Bailey, Noah Eckman, Elisa S Brunel, Carolyn K Jons, Samya Sen, Eric A Appel

Biomater Sci· February 2025

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Water-Enhancing Gels Exhibiting Heat-Activated Formation of Silica Aerogels for Protection of Critical Infrastructure During Catastrophic Wildfire.
Changxin Dong, Andrea I d'Aquino, Samya Sen, Ian A Hall, Anthony C Yu, Eric A Appel

Adv Mater· October 2024

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