Publications by authors named "Eric Chiao"

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Somatic and intergenerational G4C2 hexanucleotide repeat instability in a human C9orf72 knock-in mouse model.
Nada Kojak, Junko Kuno, Kristina E Fittipaldi, Ambereen Khan, David Wenger, Eric Chiao

Nucleic Acids Res· June 2024

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Production of large, defined genome modifications in rats by targeting rat embryonic stem cells.
Jeffrey Lee, Jingjing Wang, Roxanne Ally, Sean Trzaska, Joseph Hickey, Eric Chiao

Stem Cell Reports· January 2023

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Homozygous ALS-linked FUS P525L mutations cell- autonomously perturb transcriptome profile and chemoreceptor signaling in human iPSC microglia.
Sze Yen Kerk, Yu Bai, Janell Smith, Pranav Lalgudi, Charleen Hunt, Eric Chiao

Stem Cell Reports· March 2022

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Assessment of the role of afucosylated glycoforms on the antibody-dependent phagocytosis activity of an antibody to Aβ aggregates.
Allyson Kwiatkowski, Carl Co, Sei Kameoka, An Zhang, John Coughlin, Eric Chiao

MAbs· July 2021

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Tissue-specific activation of gene expression by the Synergistic Activation Mediator (SAM) CRISPRa system in mice.
Charleen Hunt, Suzanne A Hartford, Derek White, Evangelos Pefanis, Timothy Hanna, Eric Chiao

Nat Commun· May 2021

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SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage.
Mohini Jangi, Christina Fleet, Patrick Cullen, Shipra V Gupta, Shila Mekhoubad, Eric Chiao

Proc Natl Acad Sci U S A· March 2017

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Using ovality to predict nonmutagenic, orally efficacious pyridazine amides as cell specific spleen tyrosine kinase inhibitors.
Matthew C Lucas, Niala Bhagirath, Eric Chiao, David M Goldstein, Johannes C Hermann

J Med Chem· March 2014

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A high-throughput screen for teratogens using human pluripotent stem cells.
Sei Kameoka, Joshua Babiarz, Kyle Kolaja, Eric Chiao

Toxicol Sci· January 2014

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Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model.
Liang Guo, Luke Coyle, Rory M C Abrams, Raymond Kemper, Eric T Chiao

Toxicol Sci· December 2013

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The effects of jaspamide on human cardiomyocyte function and cardiac ion channel activity.
Karen Schweikart, Liang Guo, Zachary Shuler, Rory Abrams, Eric T Chiao

Toxicol In Vitro· March 2013

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Pyrrolopyrazines as selective spleen tyrosine kinase inhibitors.
Fernando Padilla, Niala Bhagirath, Shaoqing Chen, Eric Chiao, David M Goldstein

J Med Chem· February 2013

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Determination of the human cardiomyocyte mRNA and miRNA differentiation network by fine-scale profiling.
Joshua E Babiarz, Morgane Ravon, Sriram Sridhar, Palanikumar Ravindran, Brad Swanson, Eric Chiao

Stem Cells Dev· July 2012

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Skeletogenic phenotype of human Marfan embryonic stem cells faithfully phenocopied by patient-specific induced-pluripotent stem cells.
Natalina Quarto, Brian Leonard, Shuli Li, Melanie Marchand, Erica Anderson, Eric Chiao

Proc Natl Acad Sci U S A· January 2012

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Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage.

Nat Biotechnol· November 2011

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Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes.
Liang Guo, Rory M C Abrams, Joshua E Babiarz, Jennifer D Cohen, Sei Kameoka, Eric Chiao

Toxicol Sci· September 2011

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Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells.
Yohei Shimono, Maider Zabala, Robert W Cho, Neethan Lobo, Piero Dalerba, Eric Chiao

Cell· August 2009

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Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver.
Alayne L Brunner, David S Johnson, Si Wan Kim, Anton Valouev, Timothy E Reddy, Eric Chiao

Genome Res· June 2009

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Viral infection of human progenitor and liver-derived cells encapsulated in three-dimensional PEG-based hydrogel.
Nam-Joon Cho, Menashe Elazar, Anming Xiong, Wonjae Lee, Eric Chiao

Biomed Mater· February 2009

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Isolation and transcriptional profiling of purified hepatic cells derived from human embryonic stem cells.
Eric Chiao, Menashe Elazar, Yi Xing, Anming Xiong, Muriel Kmet

Stem Cells· August 2008

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Derivation of human embryonic stem cells in standard and chemically defined conditions.
Eric Chiao, Muriel Kmet, Barry Behr, Julie Baker

Methods Cell Biol· July 2008

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High-throughput functional screen of mouse gastrula cDNA libraries reveals new components of endoderm and mesoderm specification.
Eric Chiao, Jeff Leonard, Kari Dickinson, Julie C Baker

Genome Res· January 2005

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Overgrowth of a mouse model of the Simpson-Golabi-Behmel syndrome is independent of IGF signaling.
Eric Chiao, Peter Fisher, Laura Crisponi, Manila Deiana, Ioannis Dragatsis

Dev Biol· March 2002

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