Publications by authors named "Eric Destexhe"

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A platform approach as a plausible option for nonclinical safety assessment of adjuvanted vaccines.
Eric Destexhe

NPJ Vaccines· August 2025

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Are Repeat-Dose Toxicity Studies Informative for Safety Assessment of Vaccine Candidates? A Survey of Vaccine Developers.
Cynthia M Rohde, Eric Destexhe, Jan Willem van der Laan, Sarah Gould, Rachel Coe

Int J Toxicol· April 2025

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Repeated-Dose Toxicity, Biodistribution, and Shedding Assessments With a ChAd155 Respiratory Syncytial Virus Vaccine Candidate Evaluated in Rabbits and Rats.
Alan H Stokes, Camille Planty, Johanne Pion, Philippe Ancian, Alexandra Rogue, Eric Destexhe

Int J Toxicol· August 2022

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Lack of effects on female fertility or pre- and postnatal development of offspring in rats after exposure to AS03-adjuvanted recombinant plant-derived virus-like particle vaccine candidate for COVID-19.
Charlotte Dubé, Sarah Paris-Robidas, Iryna Primakova, Eric Destexhe, Brian J Ward

Reprod Toxicol· January 2022

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Nonclinical safety assessment of repeated administration and biodistribution of ChAd3-EBO-Z Ebola candidate vaccine.
Camille Planty, Guillaume Chevalier, Marie-Ève Duclos, Clémentine Chalmey, Catherine Thirion-Delalande, Eric Destexhe

J Appl Toxicol· June 2020

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Chimeric hemagglutinin supra-seasonal universal influenza vaccine candidates administered sequentially by the intramuscular route are locally and systemically well-tolerated in rabbits.
Éric Destexhe, Émilie Grosdidier, Adèle Bouhraoua, Catherine Thirion-Delalande, Badiaa Bouzya

Regul Toxicol Pharmacol· June 2020

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Oral Vaccination with Replication-Competent Adenovirus in Mice Reveals Dissemination of the Viral Vaccine beyond the Gastrointestinal Tract.
Emeline Goffin, Justine Javaux, Eric Destexhe, Carla D Pretto, Katherine R Spindler

J Virol· July 2019

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Signal management in pharmacovigilance and human risk assessment of CpG 7909, integrating embryo-fetal and post-natal developmental toxicity studies in rats and rabbits.
Frédérique Delannois, Camille Planty, Giulia Giordano, Eric Destexhe, Dinesh Stanislaus

Reprod Toxicol· January 2018

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Intramuscularly administered herpes zoster subunit vaccine has no effects on fertility, pre- and post-natal development in Sprague-Dawley rats.
Lawrence Segal, Karen Thacker, Michel Fochesato, Giulia Giordano, Nathalie Garçon, Eric Destexhe

Reprod Toxicol· April 2017

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Non-clinical safety assessment of single and repeated administration of gE/AS01 zoster vaccine in rabbits.
Giulia Giordano, Lawrence Segal, Menk Prinsen, Marcel V W Wijnands, Nathalie Garçon, Eric Destexhe

J Appl Toxicol· February 2017

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Evaluation of the potential effects of AS03-adjuvanted A(H1N1)pdm09 vaccine administration on the central nervous system of non-primed and A(H1N1)pdm09-primed cotton rats.
Camille Planty, Corey P Mallett, Kevin Yim, Jorge C G Blanco, Marina Boukhvalova, Eric Destexhe

Hum Vaccin Immunother· January 2017

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Non-clinical safety and biodistribution of AS03-adjuvanted inactivated pandemic influenza vaccines.
Lawrence Segal, Sandrine Wouters, Danielle Morelle, Gaëlle Gautier, Julien Le Gal, Eric Destexhe

J Appl Toxicol· December 2015

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Non-clinical safety assessment of single and repeated intramuscular administration of a human papillomavirus-16/18 vaccine in rabbits and rats.
Lawrence Segal, Danielle Morelle, Kari Kaaber, Eric Destexhe, Nathalie Garçon

J Appl Toxicol· December 2015

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Effects of Adjuvant Systems on the cardiovascular and respiratory functions in telemetered conscious dogs and anaesthetised rats.
Lawrence Segal, Virginie Roger, Colin Williams, Eric Destexhe, Nathalie Garçon

Regul Toxicol Pharmacol· October 2015

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Non-clinical safety evaluation of single and repeated intramuscular administrations of MAGE-A3 Cancer Immunotherapeutic in rabbits and cynomolgus monkeys.
Eric Destexhe, Emilie Grosdidier, Nathalie Baudson, Roy Forster, Catherine Gerard

J Appl Toxicol· July 2015

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Narcolepsy and A(H1N1)pdm09 vaccination: shaping the research on the observed signal.
Robbert van der Most, Marcelle Van Mechelen, Eric Destexhe, Martine Wettendorff, Emmanuel Hanon

Hum Vaccin Immunother· March 2015

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Local tolerance and systemic toxicity of single and repeated intramuscular administrations of two different formulations of the RTS,S malaria candidate vaccine in rabbits.
Lawrence Segal, Danielle Morelle, Mark Blee, Emma Moore, Micaela Damsten, Eric Destexhe

Regul Toxicol Pharmacol· March 2015

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Evaluation of C-reactive protein as an inflammatory biomarker in rabbits for vaccine nonclinical safety studies.
Eric Destexhe, Menk K Prinsen, Inge van Schöll, C Frieke Kuper, Nathalie Garçon

J Pharmacol Toxicol Methods· September 2014

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