Publications by authors named "Eric Huntzinger"

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HELZ2: a new, interferon-regulated, human 3'-5' exoribonuclease of the RNB family is expressed from a non-canonical initiation codon.
Eric Huntzinger, Jordan Sinteff, Bastien Morlet, Bertrand Séraphin

Nucleic Acids Res· September 2023

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Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation.
Amy E O'Connell, Maxim V Gerashchenko, Marie-Francoise O'Donohue, Samantha M Rosen, Eric Huntzinger

PLoS Genet· February 2019

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miRISC and the CCR4-NOT complex silence mRNA targets independently of 43S ribosomal scanning.
Duygu Kuzuoğlu-Öztürk, Dipankar Bhandari, Eric Huntzinger, Maria Fauser, Sigrun Helms

EMBO J· June 2016

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An asymmetric PAN3 dimer recruits a single PAN2 exonuclease to mediate mRNA deadenylation and decay.
Stefanie Jonas, Mary Christie, Daniel Peter, Dipankar Bhandari, Belinda Loh, Eric Huntzinger

Nat Struct Mol Biol· July 2014

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Structure of the PAN3 pseudokinase reveals the basis for interactions with the PAN2 deadenylase and the GW182 proteins.
Mary Christie, Andreas Boland, Eric Huntzinger, Oliver Weichenrieder, Elisa Izaurralde

Mol Cell· August 2013

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The role of GW182 proteins in miRNA-mediated gene silencing.
Joerg E Braun, Eric Huntzinger, Elisa Izaurralde

Adv Exp Med Biol· March 2013

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The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets.
Eric Huntzinger, Duygu Kuzuoglu-Öztürk, Joerg E Braun, Ana Eulalio, Lara Wohlbold

Nucleic Acids Res· January 2013

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A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation.
Joerg E Braun, Vincent Truffault, Andreas Boland, Eric Huntzinger, Chung-Te Chang

Nat Struct Mol Biol· December 2012

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A molecular link between miRISCs and deadenylases provides new insight into the mechanism of gene silencing by microRNAs.
Joerg E Braun, Eric Huntzinger, Elisa Izaurralde

Cold Spring Harb Perspect Biol· December 2012

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The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex.
Alain-Pierre Petit, Lara Wohlbold, Praveen Bawankar, Eric Huntzinger, Steffen Schmidt

Nucleic Acids Res· November 2012

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The Caenorhabditis elegans GW182 protein AIN-1 interacts with PAB-1 and subunits of the PAN2-PAN3 and CCR4-NOT deadenylase complexes.
Duygu Kuzuoglu-Öztürk, Eric Huntzinger, Steffen Schmidt, Elisa Izaurralde

Nucleic Acids Res· July 2012

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GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets.
Joerg E Braun, Eric Huntzinger, Maria Fauser, Elisa Izaurralde

Mol Cell· October 2011

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Crystal structure of the MID-PIWI lobe of a eukaryotic Argonaute protein.
Andreas Boland, Eric Huntzinger, Steffen Schmidt, Elisa Izaurralde, Oliver Weichenrieder

Proc Natl Acad Sci U S A· June 2011

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Gene silencing by microRNAs: contributions of translational repression and mRNA decay.
Eric Huntzinger, Elisa Izaurralde

Nat Rev Genet· February 2011

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Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing.
Eric Huntzinger, Joerg E Braun, Susanne Heimstädt, Latifa Zekri, Elisa Izaurralde

EMBO J· December 2010

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Role of GW182 proteins and PABPC1 in the miRNA pathway: a sense of déjà vu.
Felix Tritschler, Eric Huntzinger, Elisa Izaurralde

Nat Rev Mol Cell Biol· May 2010

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The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release.
Latifa Zekri, Eric Huntzinger, Susanne Heimstädt, Elisa Izaurralde

Mol Cell Biol· December 2009

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Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival.
Nadine Wittkopp, Eric Huntzinger, Catrin Weiler, Jérôme Saulière, Steffen Schmidt

Mol Cell Biol· July 2009

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Staphylococcus aureus endoribonuclease III purification and properties.
Clément Chevalier, Eric Huntzinger, Pierre Fechter, Sandrine Boisset, François Vandenesch

Methods Enzymol· March 2009

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Deadenylation is a widespread effect of miRNA regulation.
Ana Eulalio, Eric Huntzinger, Tadashi Nishihara, Jan Rehwinkel, Maria Fauser

RNA· January 2009

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SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan.
Eric Huntzinger, Isao Kashima, Maria Fauser, Jérôme Saulière, Elisa Izaurralde

RNA· December 2008

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GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay.
Ana Eulalio, Eric Huntzinger, Elisa Izaurralde

Nat Struct Mol Biol· April 2008

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Getting to the root of miRNA-mediated gene silencing.
Ana Eulalio, Eric Huntzinger, Elisa Izaurralde

Cell· January 2008

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Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing.
Ana Eulalio, Jan Rehwinkel, Mona Stricker, Eric Huntzinger, Schu-Fee Yang

Genes Dev· October 2007

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Delving into the diversity of silencing pathways. Symposium on MicroRNAs and siRNAs: biological functions and mechanisms.
Silke Dorner, Ana Eulalio, Eric Huntzinger, Elisa Izaurralde

EMBO Rep· August 2007

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