Publications by authors named "Eric Jnoff"

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Discovery of UCB9386: A Potent, Selective, and Brain-Penetrant Nuak1 Inhibitor Suitable for Pharmacological Studies.
Karine G Poullennec, Eric Jnoff, Jan Abendroth, Naresh Bhuma, Mark Calmiano

J Med Chem· December 2024

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Identification of ß-Glucocerebrosidase Activators for Glucosylceramide hydrolysis.
Monika-Sarah E D Schulze, Diana Scholz, Eric Jnoff, Adrian Hall, Jonathan Melin

ChemMedChem· April 2024

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Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.
Melissa L Boby, Daren Fearon, Matteo Ferla, Mihajlo Filep, Lizbé Koekemoer, Eric Jnoff

Science· November 2023

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Discovery of a small molecule modulator of the Kv1.1/Kvβ1 channel complex that reduces neuronal excitability and in vitro epileptiform activity.
Isabelle Niespodziany, Brice Mullier, Véronique Marie André, Philippe Ghisdal, Eric Jnoff

CNS Neurosci Ther· April 2019

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Back-up strategies in drug discovery: what, how and when?
Laurent Provins, Eric Jnoff, Christophe Genicot

Drug Discov Today· November 2014

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Advantageous safety profile of a dual selective alpha(2C) agonist/alpha(2A) antagonist antinociceptive agent.
Annie Delaunois, Pierrette De Ron, Paul Dedoncker, Marie-Luce Rosseels, Miranda Cornet, Eric Jnoff

Fundam Clin Pharmacol· August 2014

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Discovery of heterocyclic nonacetamide synaptic vesicle protein 2A (SV2A) ligands with single-digit nanomolar potency: opening avenues towards the first SV2A positron emission tomography (PET) ligands.
Joël Mercier, Laurence Archen, Véronique Bollu, Stéphane Carré, Yves Evrard, Eric Jnoff

ChemMedChem· April 2014

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Binding mode and structure-activity relationships around direct inhibitors of the Nrf2-Keap1 complex.
Eric Jnoff, Claudia Albrecht, John J Barker, Oliver Barker, Edward Beaumont

ChemMedChem· April 2014

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Discovery of selective alpha(2C) adrenergic receptor agonists.
Eric Jnoff, Bernard Christophe, Philippe Collart, Francis Coloretti, Aurel Debeuckelaere

ChemMedChem· March 2012

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Multicomponent reactions for the synthesis of complex piperidine scaffolds.
Wei Zhu, Marisa Mena, Eric Jnoff, Na Sun, Patrick Pasau

Angew Chem Int Ed Engl· October 2009

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