Publications by authors named "Eric Lander"

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PD-1 blockade during T cell priming enhances long-term protection against metastatic tumors by epigenetically tuning T cell exhaustion.
Teresa Dinter, Sebastian Mackowiak, Zachary J Rogers, Vidit Bhandarkar, Molly Y Carney, Eric Lander

bioRxiv· November 2025

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Efficiently quantifying dependence in massive scientific datasets using InterDependence Scores.
Adityanarayanan Radhakrishnan, Yajit Jain, Caroline Uhler, Eric S Lander

Proc Natl Acad Sci U S A· August 2025

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Rewriting regulatory DNA to dissect and reprogram gene expression.
Gabriella E Martyn, Michael T Montgomery, Hank Jones, Katherine Guo, Benjamin R Doughty, Eric S Lander

Cell· June 2025

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Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes.
Jorge Diego Martin-Rufino, Alexis Caulier, Seayoung Lee, Nicole Castano, Emily King, Eric S Lander

Science· April 2025

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Circulating Tumor DNA as a Prognostic Biomarker for Recurrence in Patients With Locoregional Esophagogastric Cancers With a Pathologic Complete Response.
Eric Michael Lander, Vasily N Aushev, Brandon M Huffman, Diana Hanna, Punashi Dutta

JCO Precis Oncol· December 2024

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A standing platform for cancer drug development using ctDNA-based evidence of recurrence.
Arielle J Medford, Ariel B Carmeli, Alexandra Ritchie, Nikhil Wagle, Levi Garraway, Eric S Lander

Nat Rev Cancer· November 2024

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Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes.
Jorge Diego Martin-Rufino, Alexis Caulier, Seayoung Lee, Nicole Castano, Emily King, Eric S Lander

bioRxiv· September 2024

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Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation.
Ali Akbari, Alison R Barton, Steven Gazal, Zheng Li, Mohammadreza Kariminejad, Eric S Lander

bioRxiv· September 2024

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Cohesin-mediated 3D contacts tune enhancer-promoter regulation.
Philine Guckelberger, Benjamin R Doughty, Glen Munson, Suhas S P Rao, Yingxuan Tan, Eric S Lander

bioRxiv· July 2024

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Advancing early onset colorectal cancer research: research advocacy, health disparities, and scientific imperatives.
Andrea J Dwyer, Aniruddha Rathod, Carli King, F E R Vuik, Phuong Gallagher, Eric M Lander

Front Oncol· July 2024

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Functional dissection of complex and molecular trait variants at single nucleotide resolution.
Layla Siraj, Rodrigo I Castro, Hannah Dewey, Susan Kales, Thanh Thanh L Nguyen, Eric S Lander

bioRxiv· May 2024

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Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever.
Dylan Kotliar, Siddharth Raju, Shervin Tabrizi, Ikponmwosa Odia, Augustine Goba, Eric S Lander

Nat Microbiol· March 2024

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Gastroesophageal Adenocarcinomas With Defective Mismatch Repair: Current Knowledge and Clinical Management.
Matthew R Strickland, Eric M Lander, Michael K Gibson, David H Ilson, Jaffer A Ajani

J Natl Compr Canc Netw· March 2024

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Convergence of coronary artery disease genes onto endothelial cell programs.
Gavin R Schnitzler, Helen Kang, Shi Fang, Ramcharan S Angom, Vivian S Lee-Kim, Eric S Lander

Nature· February 2024

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Rewriting regulatory DNA to dissect and reprogram gene expression.
Gabriella E Martyn, Michael T Montgomery, Hank Jones, Katherine Guo, Benjamin R Doughty, Eric S Lander

bioRxiv· December 2023

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Esophageal Cancer: Overview, Risk Factors, and Reasons for the Rise.
Steve Lander, Eric Lander, Michael K Gibson

Curr Gastroenterol Rep· November 2023

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Identification and Characterization of Avoidable Hospital Admissions in Patients With Lung Cancer.
Eric M Lander, Xuanyi Li, Li-Ching Huang, Amanda S Cass, Wade T Iams

J Natl Compr Canc Netw· October 2023

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Extremely sparse models of linkage disequilibrium in ancestrally diverse association studies.
Pouria Salehi Nowbandegani, Anthony Wilder Wohns, Jenna L Ballard, Eric S Lander, Alex Bloemendal

Nat Genet· September 2023

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Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases.
Elle M Weeks, Jacob C Ulirsch, Nathan Y Cheng, Brian L Trippe, Rebecca S Fine, Eric S Lander

Nat Genet· August 2023

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Massively parallel base editing to map variant effects in human hematopoiesis.
Jorge D Martin-Rufino, Nicole Castano, Michael Pang, Emanuelle I Grody, Samantha Joubran, Eric S Lander

Cell· May 2023

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Using the HER2/CEP17 FISH Ratio to Predict Pathologic Complete Response Following Neoadjuvant Anti-HER2 Doublet Therapy in HER2+ Breast Cancer.
Eric M Lander, Katherine C Rappazzo, Li-Ching Huang, Jiun-Ruey Hu, Heidi Chen

Oncologist· February 2023

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Gene Sequencing Identifies Perturbation in Nitric Oxide Signaling as a Nonlipid Molecular Subtype of Coronary Artery Disease.
Amit V Khera, Minxian Wang, Mark Chaffin, Connor A Emdin, Nilesh J Samani, Eric S Lander

Circ Genom Precis Med· December 2022

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Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer's disease.
Manish D Paranjpe, Mark Chaffin, Sohail Zahid, Scott Ritchie, Jerome I Rotter, Eric S Lander

PLoS Genet· September 2022

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A patient-driven clinicogenomic partnership for metastatic prostate cancer.
Jett Crowdis, Sara Balch, Lauren Sterlin, Beena S Thomas, Sabrina Y Camp, Eric S Lander

Cell Genom· September 2022

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