Publications by authors named "Eric M Bindels"

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An inflammatory T-cell-stromal axis contributes to hematopoietic stem/progenitor cell failure and clonal evolution in human myelodysplastic syndrome.
Lanpeng Chen, Yujie Bian, Eline Pronk, Claire van Dijk, Tim V D van Tienhoven, Eric M Bindels

Nat Commun· November 2025

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Virus-specific TRM cells of both donor and recipient origin reside in human kidney transplants.
Daphne M Hullegie-Peelen, Hector Tejeda Mora, Dennis A Hesselink, Eric Mj Bindels, Thierry Pp van den Bosch

JCI Insight· November 2023

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A Single-Cell Taxonomy Predicts Inflammatory Niche Remodeling to Drive Tissue Failure and Outcome in Human AML.
Lanpeng Chen, Eline Pronk, Claire van Dijk, Yujie Bian, Jacqueline Feyen, Eric M Bindels

Blood Cancer Discov· September 2023

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A combinatorial panel for flow cytometry-based isolation of enteric nervous system cells from human intestine.
Jonathan D Windster, Andrea Sacchetti, Gerben J Schaaf, Eric Mj Bindels, Robert Mw Hofstra

EMBO Rep· April 2023

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Efficient generation of ETX embryoids that recapitulate the entire window of murine egg cylinder development.
Cathérine Dupont, Olivier J M Schäffers, Beatrice F Tan, Sarra Merzouk, Eric M Bindels

Sci Adv· January 2023

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Single-cell analysis of cultured bone marrow stromal cells reveals high similarity to fibroblasts in situ.
Ursula S A Stalmann, Bella Banjanin, Inge A M Snoeren, James S Nagai, Nils B Leimkühler, Eric M Bindels

Exp Hematol· June 2022

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The tumor suppressor MIR139 is silenced by POLR2M to promote AML oncogenesis.
Christiaan J Stavast, Iris van Zuijen, Elena Karkoulia, Arman Özçelik, Antoinette van Hoven-Beijen, Eric M Bindels

Leukemia· March 2022

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The miR-200c/141-ZEB2-TGFβ axis is aberrant in human T-cell prolymphocytic leukemia.
Stefan J Erkeland, Christiaan J Stavast, Joyce Schilperoord-Vermeulen, Giada Dal Collo, Harmen J G Van de Werken, Eric M Bindels

Haematologica· January 2022

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Selective Requirement of MYB for Oncogenic Hyperactivation of a Translocated Enhancer in Leukemia.
Leonie Smeenk, Sophie Ottema, Roger Mulet-Lazaro, Anja Ebert, Marije Havermans, Eric M Bindels

Cancer Discov· November 2021

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Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN.
Hélène F E Gleitz, Aurélien J F Dugourd, Nils B Leimkühler, Inge A M Snoeren, Stijn N R Fuchs, Eric M Bindels

Blood· October 2020

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Rapid in vitro generation of bona fide exhausted CD8+ T cells is accompanied by Tcf7 promotor methylation.
Manzhi Zhao, Caoimhe H Kiernan, Christopher J Stairiker, Jennifer L Hope, Leticia G Leon, Eric M Bindels

PLoS Pathog· June 2020

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MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML.
Mathijs A Sanders, Edward Chew, Christoffer Flensburg, Annelieke Zeilemaker, Sarah E Miller, Eric M Bindels

Blood· October 2018

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Gli1 Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target.
Rebekka K Schneider, Ann Mullally, Aurelien Dugourd, Fabian Peisker, Remco Hoogenboezem, Eric M Bindels

Cell Stem Cell· August 2018

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Gli1 Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target.
Rebekka K Schneider, Ann Mullally, Aurelien Dugourd, Fabian Peisker, Remco Hoogenboezem, Eric M Bindels

Cell Stem Cell· June 2017

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Deficiency of the ribosome biogenesis gene Sbds in hematopoietic stem and progenitor cells causes neutropenia in mice by attenuating lineage progression in myelocytes.
Noemi A Zambetti, Eric M J Bindels, Paulina M H Van Strien, Marijke G Valkhof, Maria N Adisty

Haematologica· October 2015

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Mutational spectrum of myeloid malignancies with inv(3)/t(3;3) reveals a predominant involvement of RAS/RTK signaling pathways.
Stefan Gröschel, Mathijs A Sanders, Remco Hoogenboezem, Annelieke Zeilemaker, Marije Havermans, Eric M J Bindels

Blood· January 2015

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EVI1 is critical for the pathogenesis of a subset of MLL-AF9-rearranged AMLs.
Eric M J Bindels, Marije Havermans, Sanne Lugthart, Claudia Erpelinck, Elizabeth Wocjtowicz

Blood· June 2012

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Involvement of G1/S cyclins in estrogen-independent proliferation of estrogen receptor-positive breast cancer cells.
Eric M J Bindels, François Lallemand, Astrid Balkenende, Desiree Verwoerd, Rob Michalides

Oncogene· November 2002

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