Publications by authors named "Eric R Fearon"

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Medroxyprogesterone Acetate Inhibits Tumorigenesis in Mouse Models of Oviductal High-Grade Serous Carcinoma.
Yali Zhai, Karan Bedi, Rong Wu, Ying Feng, Maranne E Green, Eric R Fearon

Cancers (Basel)· October 2025

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Bilateral Salpingo-Oophorectomy Is Superior to Salpingectomy Alone in Preventing Non-Tubal Tumor Development in a Mouse Model of High-Grade Serous Carcinoma.
Yali Zhai, Eric R Fearon, Kathleen R Cho

Cancers (Basel)· August 2025

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SOX9 suppresses colon cancer via inhibiting epithelial-mesenchymal transition and SOX2 induction.
Ying Feng, Ningxin Zhu, Karan Bedi, Jinju Li, Chamila Perera, Eric R Fearon

J Clin Invest· June 2025

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Defining CDK12 as a tumor suppressor and therapeutic target in mouse models of tubo-ovarian high-grade serous carcinoma.
Jean Ching-Yi Tien, Yali Zhai, Rong Wu, Yuping Zhang, Yu Chang, Eric R Fearon

Proc Natl Acad Sci U S A· June 2025

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HMGA1 acts as an epigenetic gatekeeper of ASCL2 and Wnt signaling during colon tumorigenesis.
Li Z Luo, Jung-Hyun Kim, Iliana Herrera, Shaoguang Wu, Xinqun Wu, Eric R Fearon

J Clin Invest· February 2025

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CCN6 Suppresses Metaplastic Breast Carcinoma by Antagonizing Wnt/β-Catenin Signaling to Inhibit EZH2-Driven EMT.
Maria E Gonzalez, Bryce Brophy, Ahmad Eido, Adele E Leonetti, Sabra I Djomehri, Eric R Fearon

Cancer Res· October 2024

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Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer.
Hannah N Bell, Amanda K Huber, Rashi Singhal, Navyateja Korimerla, Ryan J Rebernick, Eric R Fearon

Cell Metab· January 2023

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Aging accelerates while multiparity delays tumorigenesis in mouse models of high-grade serous carcinoma.
Xiaoman Hou, Yali Zhai, Kevin Hu, Chia-Jen Liu, Aaron Udager, Eric R Fearon

Gynecol Oncol· June 2022

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DOT1L affects colorectal carcinogenesis via altering T cell subsets and oncogenic pathway.
Danfeng Sun, Weichao Wang, Fangfang Guo, Michael R Pitter, Wan Du, Eric R Fearon

Oncoimmunology· April 2022

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Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance.
Hannah N Bell, Ryan J Rebernick, Joshua Goyert, Rashi Singhal, Miljan Kuljanin, Eric R Fearon

Cancer Cell· February 2022

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Altering the Microbiome Inhibits Tumorigenesis in a Mouse Model of Oviductal High-Grade Serous Carcinoma.
Lixing Chen, Yali Zhai, Yisheng Wang, Eric R Fearon, Gabriel Núñez

Cancer Res· June 2021

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Murine Oviductal High-Grade Serous Carcinomas Mirror the Genomic Alterations, Gene Expression Profiles, and Immune Microenvironment of Their Human Counterparts.
Kevin W McCool, Zachary T Freeman, Yali Zhai, Rong Wu, Kevin Hu, Eric R Fearon

Cancer Res· February 2020

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Cancer: Context Is Key for E-cadherin in Invasion and Metastasis.
Eric R Fearon

Curr Biol· November 2019

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Lineage tracing suggests that ovarian endosalpingiosis does not result from escape of oviductal epithelium.
Yisheng Wang, Michael S Sessine, Yali Zhai, Courtney Tipton, Kevin McCool, Eric R Fearon

J Pathol· October 2019

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Trp53 null and R270H mutant alleles have comparable effects in regulating invasion, metastasis, and gene expression in mouse colon tumorigenesis.
Jinyu Tang, Ying Feng, Rork Kuick, Megan Green, Maranne Green, Eric R Fearon

Lab Invest· October 2019

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Induction of endoplasmic reticulum stress and inhibition of colon carcinogenesis by the anti-helmintic drug rafoxanide.
Federica Laudisi, Antonio Di Grazia, Veronica De Simone, Fabio Cherubini, Alfredo Colantoni, Eric R Fearon

Cancer Lett· October 2019

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Rectal cancer sub-clones respond differentially to neoadjuvant therapy.
Lynn M Frydrych, Peter Ulintz, Armand Bankhead, Christopher Sifuentes, Joel Greenson, Eric R Fearon

Neoplasia· October 2019

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Silencing the GUCA2A-GUCY2C tumor suppressor axis in CIN, serrated, and MSI colorectal neoplasia.
Babar Bashir, Dante J Merlino, Jeffrey A Rappaport, Esteban Gnass, Juan P Palazzo, Eric R Fearon

Hum Pathol· May 2019

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An immunohistochemical approach to detect oncogenic CTNNB1 mutations in primary neoplastic tissues.
Aytekin Akyol, Günes Güner, Havva Solak Özşeker, Aynur Işık, Özge Atcı, Eric R Fearon

Lab Invest· January 2019

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MOLECULAR FEATURES AND MOUSE MODELS OF COLORECTAL CANCER.
Eric R Fearon

Trans Am Clin Climatol Assoc· December 2018

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Lymph Node Metastases in Colon Cancer Are Polyclonal.
Peter J Ulintz, Joel K Greenson, Rong Wu, Eric R Fearon, Karin M Hardiman

Clin Cancer Res· May 2018

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Thiosulfate sulfurtransferase-like domain-containing 1 protein interacts with thioredoxin.
Marouane Libiad, Nicole Motl, David L Akey, Naoya Sakamoto, Eric R Fearon

J Biol Chem· February 2018

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Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma.
Heather K Schofield, Jörg Zeller, Carlos Espinoza, Christopher J Halbrook, Annachiara Del Vecchio, Eric R Fearon

JCI Insight· January 2018

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ZBP-89 function in colonic stem cells and during butyrate-induced senescence.
Ramon Ocadiz-Ruiz, Amanda L Photenhauer, Michael M Hayes, Lin Ding, Eric R Fearon

Oncotarget· November 2017

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High-grade serous carcinomas arise in the mouse oviduct via defects linked to the human disease.
Yali Zhai, Rong Wu, Rork Kuick, Michael S Sessine, Stephanie Schulman, Eric R Fearon

J Pathol· September 2017

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