Publications by authors named "Eric Toone"

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Assessing the threat of harboring a multi-resistant IncC plasmid and the efficacy of an antibiotic targeting LpxC.
Nadine Lemaitre, Amélie Dewitte, Faniry Rakotomanimana, David Gooden, Eric Toone

Antimicrob Agents Chemother· March 2025

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Degradation of Components of the Lpt Transenvelope Machinery Reveals LPS-Dependent Lpt Complex Stability in .
Alessandra M Martorana, Elisabete C C M Moura, Paola Sperandeo, Flavia Di Vincenzo, Xiaofei Liang, Eric Toone

Front Mol Biosci· December 2021

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Curative Treatment of Severe Gram-Negative Bacterial Infections by a New Class of Antibiotics Targeting LpxC.
Nadine Lemaître, Xiaofei Liang, Javaria Najeeb, Chul-Jin Lee, Marie Titecat, Eric J Toone

mBio· July 2017

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High susceptibility of MDR and XDR Gram-negative pathogens to biphenyl-diacetylene-based difluoromethyl-allo-threonyl-hydroxamate LpxC inhibitors.
Marie Titecat, Xiaofei Liang, Chul-Jin Lee, Audrey Charlet, Didier Hocquet, Eric J Toone

J Antimicrob Chemother· October 2016

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A Scalable Synthesis of the Difluoromethyl-allo-threonyl Hydroxamate-Based LpxC Inhibitor LPC-058.
Xiaofei Liang, Ramesh Gopalaswamy, Frank Navas, Eric J Toone, Pei Zhou

J Org Chem· May 2016

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Drug design from the cryptic inhibitor envelope.
Chul-Jin Lee, Xiaofei Liang, Qinglin Wu, Javaria Najeeb, Jinshi Zhao, Eric J Toone

Nat Commun· February 2016

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Specific binding at the cellulose binding module-cellulose interface observed by force spectroscopy.
Jason R King, Carleen M Bowers, Eric J Toone

Langmuir· March 2015

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Photo-activated psoralen binds the ErbB2 catalytic kinase domain, blocking ErbB2 signaling and triggering tumor cell apoptosis.
Wenle Xia, David Gooden, Leihua Liu, Sumin Zhao, Erik J Soderblom, Eric J Toone

PLoS One· October 2014

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Structural basis of the promiscuous inhibitor susceptibility of Escherichia coli LpxC.
Chul-Jin Lee, Xiaofei Liang, Ramesh Gopalaswamy, Javaria Najeeb, Eugene D Ark, Eric J Toone

ACS Chem Biol· January 2014

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Synthesis, structure, and antibiotic activity of aryl-substituted LpxC inhibitors.
Xiaofei Liang, Chul-Jin Lee, Jinshi Zhao, Eric J Toone, Pei Zhou

J Med Chem· September 2013

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Energy biotechnology in 2013: advanced technology development for breakthroughs in fuels and chemicals production.
Eric Toone, Han de Winde

Curr Opin Biotechnol· June 2013

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Effect of compressive force on unbinding specific protein-ligand complexes with force spectroscopy.
Carleen M Bowers, David A Carlson, Monica Rivera, Robert L Clark, Eric J Toone

J Phys Chem B· May 2013

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Enthalpic signature of methonium desolvation revealed in a synthetic host-guest system based on cucurbit[7]uril.
Yi Wang, Jason R King, Pan Wu, Daniel L Pelzman, David N Beratan, Eric J Toone

J Am Chem Soc· April 2013

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A general and efficient cantilever functionalization technique for AFM molecular recognition studies.
Carleen M Bowers, David A Carlson, Alexander A Shestopalov, Robert L Clark, Eric J Toone

Biopolymers· October 2012

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An enthalpic basis of additivity in biphenyl hydroxamic acid ligands for stromelysin-1.
Erin M Wilfong, Yu Du, Eric J Toone

Bioorg Med Chem Lett· October 2012

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Multicomponent patterning of indium tin oxide.
Carleen M Bowers, Alexander A Shestopalov, Robert L Clark, Eric J Toone

ACS Appl Mater Interfaces· August 2012

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E
Exploring variation in binding of Protein A and Protein G to immunoglobulin type G by isothermal titration calorimetry.
Line Naomi Lund, Trine Christensen, Eric Toone, Gunnar Houen, Arne Staby

J Mol Recognit· February 2012

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Advances in enzymology and related areas of molecular biology. Preface.
Eric J Toone

Adv Enzymol Relat Areas Mol Biol· February 2012

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Improving upon nature: active site remodeling produces highly efficient aldolase activity toward hydrophobic electrophilic substrates.
Manoj Cheriyan, Eric J Toone, Carol A Fierke

Biochemistry· February 2012

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Derivatives of plant phenolic compound affect the type III secretion system of Pseudomonas aeruginosa via a GacS-GacA two-component signal transduction system.
Akihiro Yamazaki, Jin Li, Quan Zeng, Devanshi Khokhani, William C Hutchins, Eric J Toone

Antimicrob Agents Chemother· January 2012

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Soft lithographic functionalization and patterning oxide-free silicon and germanium.
Carleen M Bowers, Eric J Toone, Robert L Clark, Alexander A Shestopalov

J Vis Exp· December 2011

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Directed evolution of a pyruvate aldolase to recognize a long chain acyl substrate.
Manoj Cheriyan, Matthew J Walters, Brian D Kang, Laura L Anzaldi, Eric J Toone

Bioorg Med Chem· November 2011

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A multidisciplinary approach to probing enthalpy-entropy compensation and the interfacial mobility model.
Erin M Wilfong, Yuri Kogiso, Sivaramakrishnan Muthukrishnan, Thomas Kowatz, Yu Du, Eric J Toone

J Am Chem Soc· August 2011

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Bacterial infection remains a leading cause of death in both Western and developing world. Preface.
Eric J Toone

Adv Enzymol Relat Areas Mol Biol· July 2011

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