Publications by authors named "Erickson Paragas"

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Characterization of small molecule drug clearance mechanisms using in vitro and in vivo approaches in drug discovery and development.
Cindy Yanfei Li, Nashid Farhan, Erickson M Paragas, Hiranmayee Kandala, Upendra P Dahal

Expert Opin Drug Metab Toxicol· December 2025

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Assessing and mitigating pH-mediated DDI risks in drug development - formulation approaches and clinical considerations.
Di Wu, Jiaying Liu, Erickson M Paragas, Jaydeep Yadav, Theresa Aliwarga

Drug Metab Rev· August 2025

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Enzyme-mediated drug-drug interactions: a review of and methodologies, regulatory guidance, and translation to the clinic.
Jaydeep Yadav, Benjamin J Maldonato, Joseph M Roesner, Ana G Vergara, Erickson M Paragas

Drug Metab Rev· August 2025

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Epigenetics in drug disposition & drug therapy: symposium report of the 24 North American meeting of the International Society for the Study of Xenobiotics (ISSX).
Benjamin J Maldonato, Ana G Vergara, Jaydeep Yadav, Sarah M Glass, Erickson M Paragas

Drug Metab Rev· August 2022

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Complex Cytochrome P450 Kinetics Due to Multisubstrate Binding and Sequential Metabolism. Part 1. Theoretical Considerations.
Zeyuan Wang, Erickson M Paragas, Swati Nagar, Ken Korzekwa

Drug Metab Dispos· December 2021

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Complex Cytochrome P450 Kinetics Due to Multisubstrate Binding and Sequential Metabolism. Part 2. Modeling of Experimental Data.
Erickson M Paragas, Zeyuan Wang, Ken Korzekwa, Swati Nagar

Drug Metab Dispos· December 2021

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Enzyme Kinetics, Pharmacokinetics, and Inhibition of Aldehyde Oxidase.
Erickson M Paragas, Kanika Choughule, Jeffrey P Jones, John T Barr

Methods Mol Biol· August 2021

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Aldehyde Oxidase Contributes to All--Retinoic Acid Biosynthesis in Human Liver.
Guo Zhong, Chris J Seaman, Erickson M Paragas, Huaqing Xi, Karla-Luise Herpoldt

Drug Metab Dispos· March 2021

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Time-dependent enzyme inactivation: Numerical analyses of in vitro data and prediction of drug-drug interactions.
Jaydeep Yadav, Erickson Paragas, Ken Korzekwa, Swati Nagar

Pharmacol Ther· February 2020

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Time Course of Aldehyde Oxidase and Why It Is Nonlinear.
Armina Abbasi, Erickson M Paragas, Carolyn A Joswig-Jones, John T Rodgers, Jeffrey P Jones

Drug Metab Dispos· May 2019

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Kinetic mechanism of time-dependent inhibition of CYP2D6 by 3,4-methylenedioxymethamphetamine (MDMA): Functional heterogeneity of the enzyme and the reversibility of its inactivation.
John T Rodgers, Nadezhda Y Davydova, Erickson M Paragas, Jeffrey P Jones, Dmitri R Davydov

Biochem Pharmacol· October 2018

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The two faces of aldehyde oxidase: Oxidative and reductive transformations of 5-nitroquinoline.
Erickson M Paragas, Sara C Humphreys, Joshua Min, Carolyn A Joswig-Jones, Jeffrey P Jones

Biochem Pharmacol· December 2017

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ecoAO: A Simple System for the Study of Human Aldehyde Oxidases Role in Drug Metabolism.
Erickson M Paragas, Sara C Humphreys, Joshua Min, Carolyn A Joswig-Jones, Silke Leimkühler

ACS Omega· August 2017

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One-pot SSA-catalyzed β-elimination: an efficient and inexpensive protocol for easy access to the glycal of sialic acid.
Erickson M Paragas, I Abrrey Monreal, Chris M Vasil, Jonel P Saludes

Carbohydr Res· January 2015

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Antitubercular constituents from Premna odorata Blanco.
Stephen B Lirio, Allan Patrick G Macabeo, Erickson M Paragas, Matthias Knorn, Paul Kohls

J Ethnopharmacol· June 2014

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