Publications by authors named "Erik Guetschow"

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Orally Bioavailable Macrocyclic Peptide That Inhibits Binding of PCSK9 to the Low Density Lipoprotein Receptor.
Douglas G Johns, Louis-Charles Campeau, Puja Banka, An Bautmans, Tjerk Bueters, Erik D Guetschow

Circulation· July 2023

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Holistic analytical characterization and risk assessment of residual host cell protein impurities in an active pharmaceutical ingredient synthesized by biocatalysts.
Fengqiang Wang, Xuanwen Li, Michael Swanson, Erik Guetschow, Matthew Winston

Biotechnol Bioeng· August 2022

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A kinase-cGAS cascade to synthesize a therapeutic STING activator.
John A McIntosh, Zhijian Liu, Brian M Andresen, Nastaran Salehi Marzijarani, Jeffrey C Moore, Erik Guetschow

Nature· March 2022

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Quantitation and speciation of residual protein within active pharmaceutical ingredients using image analysis with SDS-PAGE.
Joseph P Smith, Nicole M Ralbovsky, Mackenzie L Lauro, Erik Hoyt, Erik D Guetschow

J Pharm Biomed Anal· January 2022

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Mass Activated Droplet Sorting (MADS) Enables High-Throughput Screening of Enzymatic Reactions at Nanoliter Scale.
Daniel A Holland-Moritz, Michael K Wismer, Benjamin F Mann, Iman Farasat, Paul Devine, Erik D Guetschow

Angew Chem Int Ed Engl· March 2020

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Combination of circular dichroism spectroscopy and size-exclusion chromatography coupled with HDX-MS for studying global conformational structures of peptides in solution.
Nicole M Schiavone, Gregory F Pirrone, Erik D Guetschow, Ian Mangion, Alexey A Makarov

Talanta· March 2019

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Enabling Biocatalysis by High-Throughput Protein Engineering Using Droplet Microfluidics Coupled to Mass Spectrometry.
Xue W Diefenbach, Iman Farasat, Erik D Guetschow, Christopher J Welch, Robert T Kennedy

ACS Omega· February 2018

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An Inexpensive, Open-Source USB Arduino Data Acquisition Device for Chemical Instrumentation.
James P Grinias, Jason T Whitfield, Erik D Guetschow, Robert T Kennedy

J Chem Educ· July 2016

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Identification of sirtuin 5 inhibitors by ultrafast microchip electrophoresis using nanoliter volume samples.
Erik D Guetschow, Surinder Kumar, David B Lombard, Robert T Kennedy

Anal Bioanal Chem· January 2016

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Subsecond electrophoretic separations from droplet samples for screening of enzyme modulators.
Erik D Guetschow, Daniel J Steyer, Robert T Kennedy

Anal Chem· October 2014

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Detection of prolactin inducible protein mRNA, a biomarker for breast cancer metastasis, using a molecular beacon-based assay.
Erik D Guetschow, Will Black, Carolyn M Walsh, Jennifer R W Furchak

Anal Bioanal Chem· August 2012

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The effect of co-surfactant-modified micelles on chiral separations in EKC.
Adeline B Kojtari, Erik D Guetschow, Joe P Foley

Electrophoresis· August 2009

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