Publications by authors named "Erik Hack"

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IgM Anti-Ganglioside Binding and Complement Activation in an iPSC-Derived Motor Neuron Model for Multifocal Motor Neuropathy.
Daniëlle Krijgsman, Kim Dijkxhoorn, Elisabeth de Zeeuw, Lauri M Bloemenkamp, Jeroen W Bos, C Erik Hack

Neurol Neuroimmunol Neuroinflamm· January 2026

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Randomized phase I trial outcomes show safe and sustainable inhibition of classical and lectin complement pathways by empasiprubart.
Inge Van de Walle, Laura Bracke, Heidi Gytz Olesen, Tonke van Bragt, Stéphanie Cadour, C Erik Hack

Nat Commun· August 2025

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Complement activation by IgM autoantibodies linked to immune-mediated neuropathies depends on C2.
Kevin Budding, Kim Dijkxhoorn, Elisabeth de Zeeuw, Lauri M Bloemenkamp, W Ludo van der Pol, C Erik Hack

Eur J Neurol· January 2025

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IgM anti-GM2 antibodies in patients with multifocal motor neuropathy target Schwann cells and are associated with early onset.
Kevin Budding, Jeroen W Bos, Kim Dijkxhoorn, Elisabeth de Zeeuw, Lauri M Bloemenkamp, C Erik Hack

J Neuroinflammation· April 2024

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Human IAPP is a contributor to painful diabetic peripheral neuropathy.
Mohammed Mh Albariqi, Sabine Versteeg, Elisabeth M Brakkee, J Henk Coert, Barend Ow Elenbaas, C Erik Hack

J Clin Invest· April 2023

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Recombinant human C1 esterase inhibitor as prophylactic treatment in idiopathic non-histaminergic angioedema.
Mehran Alizadeh Aghdam, Zonne L M Hofman, Michelle Meertens, Ans Lebens, C Erik Hack

Allergy· December 2022

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Anti-C2 Antibody ARGX-117 Inhibits Complement in a Disease Model for Multifocal Motor Neuropathy.
Kevin Budding, Lill Eva Johansen, Inge Van de Walle, Kim Dijkxhoorn, Elisabeth de Zeeuw, C Erik Hack

Neurol Neuroimmunol Neuroinflamm· January 2022

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Anti-PEG antibodies compromise the integrity of PEGylated lipid-based nanoparticles via complement.
Mariona Estapé Senti, Caroline A de Jongh, Kim Dijkxhoorn, Johan J F Verhoef, Janos Szebeni, C Erik Hack

J Control Release· January 2022

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A generic sample preparation method for the multiplex analysis of seven therapeutic monoclonal antibodies in human plasma or serum with liquid chromatography-tandem mass spectrometry.
Mohsin El Amrani, Laszlo Gerencser, Alwin D R Huitema, C Erik Hack, Matthijs van Luin

J Chromatogr A· October 2021

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CXCL4 Links Inflammation and Fibrosis by Reprogramming Monocyte-Derived Dendritic Cells .
Sandra C Silva-Cardoso, Weiyang Tao, Chiara Angiolilli, Ana P Lopes, Cornelis P J Bekker, Erik Hack

Front Immunol· May 2021

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ARGX-117, a therapeutic complement inhibiting antibody targeting C2.
Inge Van de Walle, Karen Silence, Kevin Budding, Liesbeth Van de Ven, Kim Dijkxhoorn, C Erik Hack

J Allergy Clin Immunol· April 2021

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Cytokine receptor clustering in sensory neurons with an engineered cytokine fusion protein triggers unique pain resolution pathways.
Judith Prado, Remco H S Westerink, Jelena Popov-Celeketic, Cristine Steen-Louws, Aridaman Pandit, C Erik Hack

Proc Natl Acad Sci U S A· March 2021

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Detecting oral kallikrein-targeting therapy through triggered contact activation: A phase I study.
Zonne L M Hofman, Chantal C Clark, C Erik Hack, Steven de Maat, Coen Maas

J Allergy Clin Immunol· December 2020

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Increased intra-articular granzyme M may trigger local IFN-λ1/IL-29 response in rheumatoid arthritis.
Liling Shan, Lucas L van den Hoogen, Jan Meeldijk, Helena M Kok, Lieneke H Jongeneel, C Erik Hack

Clin Exp Rheumatol· April 2020

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Evidence for bradykinin release in chronic spontaneous urticaria.
Zonne L M Hofman, Mignon T van den Elzen, Jeffrey Kuijpers, Steven de Maat, C Erik Hack

Clin Exp Allergy· March 2020

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Quantification of T Cell Binding Polyclonal Rabbit Anti-thymocyte Globulin in Human Plasma with Liquid Chromatography Tandem-Mass Spectrometry.
Mohsin El Amrani, Rick Admiraal, Lobke Willaert, Lysette J C Ebskamp-van Raaij, Amelia M Lacna, C Erik Hack

AAPS J· February 2020

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A mutation in the kringle domain of human factor XII that causes autoinflammation, disturbs zymogen quiescence, and accelerates activation.
Zonne L M Hofman, Chantal C Clark, Wariya Sanrattana, Aziz Nosairi, Naomi M J Parr, C Erik Hack

J Biol Chem· January 2020

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Sialic Acid-Engineered IL4-10 Fusion Protein is Bioactive and Rapidly Cleared from the Circulation.
Cristine Steen-Louws, Peter Boross, Judith Prado, Jan Meeldijk, Jurgen B Langenhorst, C Erik Hack

Pharm Res· December 2019

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Six-step workflow for the quantification of therapeutic monoclonal antibodies in biological matrices with liquid chromatography mass spectrometry - A tutorial.
Mohsin El Amrani, Anouk A M Donners, C Erik Hack, Alwin D R Huitema, Erik M van Maarseveen

Anal Chim Acta· November 2019

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The Autoimmune-Associated Single Nucleotide Polymorphism Within Correlates With Clinical Outcome After Lung Transplantation.
Kevin Budding, Jessica van Setten, Eduard A van de Graaf, Oliver A van Rossum, Tineke Kardol-Hoefnagel, C Erik Hack

Front Immunol· October 2019

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Simultaneous Quantification of Free Adalimumab and Infliximab in Human Plasma Using a Target-Based Sample Purification and Liquid Chromatography-Tandem Mass Spectrometry.
Mohsin El Amrani, Sabine M Bosman, Annelies C Egas, C Erik Hack, Alwin D R Huitema

Ther Drug Monit· October 2019

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High occurrence of antihistamine resistance in patients with recurrent idiopathic angioedema.
Zonne L M Hofman, Nikki van West, C Erik Hack, André C Knulst, Coen Maas

Clin Transl Allergy· July 2019

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Inflammatory response and optimalisation of perioperative fluid administration during hyperthermic intraoperative intraperitoneal chemotherapy surgery.
Piet de Witte, Christien A de Witt, Johan L van de Minkelis, Djamila Boerma, H Frank Solinger, C Erik Hack

J Gastrointest Oncol· April 2019

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Quantification of neutralizing anti-drug antibodies and their neutralizing capacity using competitive displacement and tandem mass spectrometry: Infliximab as proof of principle.
Mohsin El Amrani, Camiel Göbel, Annelies C Egas, Stefan Nierkens, C Erik Hack

J Transl Autoimmun· April 2019

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Effect of cytomegalovirus reactivation on the time course of systemic host response biomarkers in previously immunocompetent critically ill patients with sepsis: a matched cohort study.
Kirsten van de Groep, Stefan Nierkens, Olaf L Cremer, Linda M Peelen, Peter M C Klein Klouwenberg, C Erik Hack

Crit Care· December 2018

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