Publications by authors named "Erin Flynt"

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Multiple cereblon genetic changes are associated with acquired resistance to lenalidomide or pomalidomide in multiple myeloma.
Sarah Gooding, Naser Ansari-Pour, Fadi Towfic, María Ortiz Estévez, Philip P Chamberlain, Kao-Tai Tsai, Erin Flynt, Marissa Hirst, Dan Rozelle, Paula Dhiman

Blood· January 2021

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Distinct patient, tumour and chimeric antigen receptor T-cell characteristics are associated with initiating versus sustaining responses to idecabtagene vicleucel in relapsed and refractory multiple myeloma.
Nathan Martin, Ethan Thompson, Nicholas Stong, Yang Xu, Olivia Finney, Erin Flynt

Br J Haematol· September 2025

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Iberdomide increases innate and adaptive immune cell subsets in the bone marrow of patients with relapsed/refractory multiple myeloma.
Oliver Van Oekelen, Michael Amatangelo, Manman Guo, Bhaskar Upadhyaya, Adam P Cribbs, Erin Flynt

Cell Rep Med· June 2024

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Pharmacodynamic changes in tumor and immune cells drive iberdomide's clinical mechanisms of activity in relapsed and refractory multiple myeloma.
Michael Amatangelo, Erin Flynt, Nicholas Stong, Pradipta Ray, Oliver Van Oekelen

Cell Rep Med· June 2024

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ETV4-Dependent Transcriptional Plasticity Maintains MYC Expression and Results in IMiD Resistance in Multiple Myeloma.
Paola Neri, Benjamin G Barwick, David Jung, Jonathan C Patton, Ranjan Maity, Erin Flynt

Blood Cancer Discov· January 2024

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The location of the t(4;14) translocation breakpoint within the NSD2 gene identifies a subset of patients with high-risk NDMM.
Nicholas Stong, María Ortiz-Estévez, Fadi Towfic, Mehmet Samur, Amit Agarwal, Erin Flynt

Blood· March 2023

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Whole-genome analysis identifies novel drivers and high-risk double-hit events in relapsed/refractory myeloma.
Naser Ansari-Pour, Mehmet Samur, Erin Flynt, Sarah Gooding, Fadi Towfic

Blood· February 2023

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Loss of COP9 signalosome genes at 2q37 is associated with IMiD resistance in multiple myeloma.
Sarah Gooding, Naser Ansari-Pour, Mohammad Kazeroun, Kubra Karagoz, Ann Polonskaia, Erin Flynt

Blood· October 2022

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Myeloma Genome Project Panel is a Comprehensive Targeted Genomics Panel for Molecular Profiling of Patients with Multiple Myeloma.
Parvathi Sudha, Aarif Ahsan, Cody Ashby, Tasneem Kausar, Akhil Khera, Erin Flynt

Clin Cancer Res· July 2022

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Multiple Myeloma Patient Tumors With High Levels of Cereblon Exon-10 Deletion Splice Variant Upregulate Clinically Targetable Pro-Inflammatory Cytokine Pathways.
Kubra Karagoz, Matthew Stokes, María Ortiz-Estévez, Fadi Towfic, Erin Flynt

Front Genet· February 2022

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Integrative multi-omics identifies high risk multiple myeloma subgroup associated with significant DNA loss and dysregulated DNA repair and cell cycle pathways.
María Ortiz-Estévez, Fadi Towfic, Erin Flynt, Nicholas Stong, In Sock Jang

BMC Med Genomics· December 2021

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Developing next generation immunomodulatory drugs and their combinations in multiple myeloma.
Anjan Thakurta, William E Pierceall, Michael D Amatangelo, Erin Flynt, Amit Agarwal

Oncotarget· July 2021

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Differential RNA splicing as a potentially important driver mechanism in multiple myeloma.
Michael A Bauer, Cody Ashby, Christopher Wardell, Eileen M Boyle, Maria Ortiz, Erin Flynt

Haematologica· March 2021

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Multiple Myeloma DREAM Challenge reveals epigenetic regulator PHF19 as marker of aggressive disease.
Mike J Mason, Carolina Schinke, Christine L P Eng, Fadi Towfic, Fred Gruber, Erin Flynt

Leukemia· July 2020

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and Mutations Associate with Adverse Outcome in a Long-term Follow-up of Patients with Multiple Myeloma.
Eileen M Boyle, Cody Ashby, Ruslana G Tytarenko, Shayu Deshpande, Hongwei Wang, Erin Flynt

Clin Cancer Res· May 2020

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Iberdomide (CC-220) is a potent cereblon E3 ligase modulator with antitumor and immunostimulatory activities in lenalidomide- and pomalidomide-resistant multiple myeloma cells with dysregulated CRBN.
Chad C Bjorklund, Jian Kang, Michael Amatangelo, Ann Polonskaia, Mark Katz, J Erin Flynt

Leukemia· April 2020

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Prognosis, Biology, and Targeting of Dysregulation in Multiple Myeloma.
Erin Flynt, Kamlesh Bisht, Vinidhra Sridharan, María Ortiz, Fadi Towfic

Cells· January 2020

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High subclonal fraction of 17p deletion is associated with poor prognosis in multiple myeloma.
Anjan Thakurta, Maria Ortiz, Pedro Blecua, Fadi Towfic, Jill Corre, Erin Flynt

Blood· March 2019

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Cereblon gene expression and correlation with clinical outcomes in patients with relapsed/refractory multiple myeloma treated with pomalidomide: an analysis of STRATUS.
Xiaozhong Qian, Meletios A Dimopoulos, Michael Amatangelo, Chad Bjorklund, Fadi Towfic, Erin Flynt

Leuk Lymphoma· February 2019

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A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis.
Brian A Walker, Konstantinos Mavrommatis, Christopher P Wardell, T Cody Ashby, Michael Bauer, Erin Flynt

Leukemia· January 2019

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Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma.
Brian A Walker, Konstantinos Mavrommatis, Christopher P Wardell, T Cody Ashby, Michael Bauer, Erin Flynt

Blood· August 2018

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Activity of lenalidomide in mantle cell lymphoma can be explained by NK cell-mediated cytotoxicity.
Patrick R Hagner, Hsiling Chiu, Maria Ortiz, Benedetta Apollonio, Maria Wang, Erin Flynt

Br J Haematol· November 2017

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