Publications by authors named "Ernst Conzelmann"

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Peroxisomal membrane channel Pxmp2 in the mammary fat pad is essential for stromal lipid homeostasis and for development of mammary gland epithelium in mice.
Miia H Vapola, Aare Rokka, Raija T Sormunen, Leena Alhonen, Werner Schmitz, Ernst Conzelmann

Dev Biol· July 2014

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Metabolic adaptation allows Amacr-deficient mice to remain symptom-free despite low levels of mature bile acids.
Eija M Selkälä, Sanna M Kuusisto, Tuire Salonurmi, Markku J Savolainen, Matti Jauhiainen, Ernst Conzelmann

Biochim Biophys Acta· August 2013

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The enolization chemistry of a thioester-dependent racemase: the 1.4 Å crystal structure of a reaction intermediate complex characterized by detailed QM/MM calculations.
Satyan Sharma, Prasenjit Bhaumik, Werner Schmitz, Rajaram Venkatesan, J Kalervo Hiltunen, Ernst Conzelmann

J Phys Chem B· March 2012

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Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis.
Ilkka J Miinalainen, Werner Schmitz, Anne Huotari, Kaija J Autio, Raija Soininen, Ernst Conzelmann

PLoS Genet· July 2009

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Proteomic analysis of cathepsin B- and L-deficient mouse brain lysosomes.
Sonja Stahl, Yvonne Reinders, Esther Asan, Walther Mothes, Ernst Conzelmann

Biochim Biophys Acta· October 2007

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The catalysis of the 1,1-proton transfer by alpha-methyl-acyl-CoA racemase is coupled to a movement of the fatty acyl moiety over a hydrophobic, methionine-rich surface.
Prasenjit Bhaumik, Werner Schmitz, Antti Hassinen, J Kalervo Hiltunen, Ernst Conzelmann

J Mol Biol· April 2007

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The human IgM antibody SAM-6 induces tumor-specific apoptosis with oxidized low-density lipoprotein.
Stephanie Brändlein, Nicole Rauschert, Leo Rasche, Angela Dreykluft, Frank Hensel, Ernst Conzelmann

Mol Cancer Ther· January 2007

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Alpha-methylacyl-CoA racemase from Mycobacterium tuberculosis. Mutational and structural characterization of the active site and the fold.
Kalle Savolainen, Prasenjit Bhaumik, Werner Schmitz, Tiina J Kotti, Ernst Conzelmann

J Biol Chem· April 2005

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A mouse model for alpha-methylacyl-CoA racemase deficiency: adjustment of bile acid synthesis and intolerance to dietary methyl-branched lipids.
Kalle Savolainen, Tiina J Kotti, Werner Schmitz, Teuvo I Savolainen, Raija T Sormunen, Ernst Conzelmann

Hum Mol Genet· May 2004

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Elevated alpha-methylacyl-CoA racemase enzymatic activity in prostate cancer.
Chandan Kumar-Sinha, Rajal B Shah, Bharathi Laxman, Scott A Tomlins, Jason Harwood, Ernst Conzelmann

Am J Pathol· March 2004

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Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2.
Simone Rost, Andreas Fregin, Vytautas Ivaskevicius, Ernst Conzelmann, Konstanze Hörtnagel

Nature· February 2004

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Crystallization and preliminary X-ray diffraction studies of an alpha-methylacyl-CoA racemase from Mycobacterium tuberculosis.
Prasenjit Bhaumik, Petri Kursula, Ville Ratas, Ernst Conzelmann, J Kalervo Hiltunen

Acta Crystallogr D Biol Crystallogr· February 2003

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Defects in degradation of blood group A and B glycosphingolipids in Schindler and Fabry diseases.
Befekadu Asfaw, Jana Ledvinová, Robert Dobrovolńy, Henk D Bakker, Robert J Desnick, Ernst Conzelmann

J Lipid Res· July 2002

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PEX1 mutations in complementation group 1 of Zellweger spectrum patients correlate with severity of disease.
Natalie Preuss, Ute Brosius, Martina Biermanns, Ania C Muntau, Ernst Conzelmann

Pediatr Res· June 2002

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The role of alpha-methylacyl-CoA racemase in bile acid synthesis.
Dean A Cuebas, Christopher Phillips, Werner Schmitz, Ernst Conzelmann, Dmitry K Novikov

Biochem J· May 2002

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