Publications by authors named "Eskandar Qaed"

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Phosphocreatine attenuates doxorubicin-induced hepatotoxicity via activation of Nrf2/HO-1 and PGC-1α pathways in mice.
Eskandar Qaed, Mueataz A Mahyoub, Waleed Q A Naji, Fu Han Wang, Wu Liu

Tissue Cell· February 2026

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Advanced glycation end products (AGEs) and their role in diabetes mellitus and related complications: mechanisms and therapeutic insights.
Eskandar Qaed, Waleed Aldahmash, Mueataz A Mahyoub

Glycoconj J· December 2025

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Phosphocreatine alleviates liver fibrosis in diabetic mice by targeting TGF-β/Smad and α-SMA pathways.
Fu Han Wang, Eskandar Qaed, Waleed Aldahmash, Mueataz A Mahyoub, Dalal Sanad Al-Mutairi

Tissue Cell· October 2025

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Phosphocreatine Mitigates Doxorubicin-Induced Neurotoxicity in Rats by Regulating Mitochondrial Function and Apoptosis via the NF-κB/PGC-1α Pathway.
Eskandar Qaed, Waleed Aldahmash, Mueataz A Mahyoub, Dalal Sanad Al-Mutairi, Zeyao Tang

Neuromolecular Med· August 2025

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Unleashing the potential of Genistein and its derivatives as effective therapeutic agents for breast cancer treatment.
Eskandar Qaed, Wu Liu, Marwan Almoiliqy, Rawan Mohamed, Zeyao Tang

Naunyn Schmiedebergs Arch Pharmacol· April 2025

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Phosphocreatine-mediated enhancement of mitochondrial function for accelerated healing of diabetic foot ulcers through the PGC-1α-NRF-1 signaling pathway.
Eskandar Qaed, Marwan Almoiliqy, Wu Liu, Jingyu Wang, Haitham Saad Al-Mashriqi

Tissue Cell· April 2025

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Sigma-1 Receptor Specific Biological Functions, Protective Role, and Therapeutic Potential in Cardiovascular Diseases.
Ahmed Almaamari, Marwa Sultan, Tao Zhang, Eskandar Qaed, Shang Wu

Cardiovasc Toxicol· April 2025

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Strategic enhancement of collagen detection using lanthanide-functionalized collagen targeted peptides.
Jean Claude Munyemana, Xiuxia Sun, Lu Li, Chunxia Zhang, Eskandar Qaed

Talanta· February 2025

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Protective effects of phosphocreatine against Doxorubicin-Induced cardiotoxicity through mitochondrial function enhancement and apoptosis suppression via AMPK/PGC-1α signaling pathway.
Eskandar Qaed, Marwan Almoiliqy, Wu Liu, Haitham Saad Al-Mashriqi, Eman Alyafeai

Int Immunopharmacol· January 2025

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Phosphocreatine ameliorates hepatocellular apoptosis mediated by protecting mitochondrial damage in liver ischemia/reperfusion injury through inhibiting TLR4 and Agonizing Akt Pathway.
Fu Han Wang, Eskandar Qaed, Waleed Aldahmash, Mueataz A Mahyoub, Zhongyuan Tang

Tissue Cell· December 2024

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Molecular dynamics of DNA repair and carcinogen interaction: Implications for cancer initiation, progression, and therapeutic strategies.
Eman Alyafeai, Eskandar Qaed, Haitham Saad Al-Mashriqi, Ahmed Almaamari, Anisa H Almansory

Mutat Res· November 2024

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Phosphocreatine attenuates doxorubicin-induced nephrotoxicity through inhibition of apoptosis, and restore mitochondrial function via activation of Nrf2 and PGC-1α pathways.
Eskandar Qaed, Ahmed Almaamari, Marwan Almoiliqy, Eman Alyafeai, Marwa Sultan

Chem Biol Interact· September 2024

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Evaluating the pharmacological activities of -Silver nanoparticles induced apoptosis against colon cancer cells (HCT-116).
Omar Hotan, Ali Alhaj, Abdulghfor Al-Quhaim, Khaled Alburaihi, Yahya Ahmed, Eskandar Qaed

Food Sci Nutr· August 2024

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Mechanism study of oleanolic acid derivative, K73-03, inducing cell apoptosis in hepatocellular carcinoma.
Jiaqi Wang, Chuchu Ma, Zhongyuan Tang, Zhengwu Sun, Eskandar Qaed

Cancer Cell Int· January 2024

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Uncovering the Therapeutic Potential of Phosphocreatine in Diabetic Retinopathy: Mitigating Mitochondrial Dysfunction and Apoptosis via JAK2/STAT3 Signaling Pathway.
Eskandar Qaed, Eman Alyafeai, Ahmed Al-Maamari, Mohamed Y Zaky, Marwan Almoiliqy

J Mol Neurosci· January 2024

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Procyanidins: A promising anti-diabetic agent with potential benefits on glucose metabolism and diabetes complications.
Eskandar Qaed, Marwan Almoiliqy, Bandar Al-Hamyari, Abdullah Qaid, Haneen Alademy

Wound Repair Regen· November 2023

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Fisetin's Promising Antitumor Effects: Uncovering Mechanisms and Targeting for Future Therapies.
Eskandar Qaed, Bandar Al-Hamyari, Ahmed Al-Maamari, Abdullah Qaid, Haneen Alademy

Glob Med Genet· September 2023

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Protective effects of phosphocreatine on human vascular endothelial cells against hydrogen peroxide-induced apoptosis and in the hyperlipidemic rat model.
Zhongyuan Tang, Zonghui Zhang, Jiaqi Wang, Zhengwu Sun, Eskandar Qaed

Chem Biol Interact· September 2023

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Research Progress and New Perspectives of Anticancer Effects of Emodin.
Wu Liu, Eskandar Qaed, Yuelin Zhu, Wenzhang Tian, Yizhen Wang

Am J Chin Med· September 2023

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Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.
Hongyan Wang, Jie Ai, Abdullah Shopit, Mengyue Niu, Nisar Ahmed, Eskandar Qaed

Cell Biol Toxicol· June 2022

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Corrigendum to 'Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways' [Free Radic. Biol. Med. 120 (2018) 228-238/ PMID: 29559323].
Hailong Li, Zhongyuan Tang, Peng Chu, Yanlin Song, Ying Yang, Eskandar Qaed

Free Radic Biol Med· February 2022

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Protective Effects of Cinnamaldehyde against Mesenteric Ischemia-Reperfusion-Induced Lung and Liver Injuries in Rats.
Marwan Almoiliqy, Jin Wen, Eskandar Qaed, Yuchao Sun, Mengqiao Lian

Oxid Med Cell Longev· September 2021

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Non-energy mechanism of phosphocreatine on the protection of cell survival.
Wu Liu, Eskandar Qaed, Han Guo Zhu, Ma Xiao Dong, ZeYao Tang

Biomed Pharmacother· September 2021

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miR-421 up-regulation by the oleanolic acid derivative K73-03 regulates epigenetically SPINK1 transcription in pancreatic cancer cells leading to metabolic changes and enhanced apoptosis.
Abdullah Shopit, Xiaodong Li, Zhongyuan Tang, Mohammed Awsh, Loubna Shobet, Eskandar Qaed

Pharmacol Res· November 2020

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Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53.
Marwan Almoiliqy, Jin Wen, Bin Xu, Yu-Chao Sun, Meng-Qiao Lian, Eskandar Qaed

Acta Pharmacol Sin· September 2020

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