Publications by authors named "Eslam Ali"

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Discovery of potential RAF selective back pocket as a promising biological site for BRAF inhibitors targeting resistant melanoma opens the door for a new generation of kinase inhibitors: Design, synthesis, biological evaluation, and in silico molecular simulation.
Usama Ammar, Mahmoud Gamal El-Din, Mohammed Abdel-Maksoud, Eslam Ali, Mohammed I El-Gamal

Int J Biol Macromol· August 2025

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ByeTAC: Bypassing E-Ligase-Targeting Chimeras for Direct Proteasome Degradation.
Cody A Loy, Eslam M H Ali, Laurence J Seabrook, Timothy J Harris, Kate A Kragness

J Med Chem· May 2025

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Structural Optimization and MD Simulation Study of Benzimidazole Derivatives as Potent Mutant FLT3 Kinase Inhibitors Targeting AML.
Nada Alaa El-Deen, RosaAnna DeFilippis, Amal Kamal Abdel-Aziz, Sandra N Milik, Suhana Patel, Eslam M H Ali

Arch Pharm (Weinheim)· May 2025

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Empowering cancer prevention with AI: unlocking new frontiers in prediction, diagnosis, and intervention.
Marianna-Foteini Dafni, Mohamed Shih, Agnes Zanotto Manoel, Mohamed Yousif Elamin Yousif, Stavroula Spathi, Swarali Yatin Chodnekar, Eslam Salih Musa Ali

Cancer Causes Control· April 2025

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ByeTAC: Bypassing an E3 Ligase for Targeted Protein Degradation.
Eslam M H Ali, Cody A Loy, Darci J Trader

bioRxiv· January 2024

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Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun N-terminal kinase (JNK) inhibitors in leukemia cells.
Karim I Mersal, Mohammed S Abdel-Maksoud, Eslam M H Ali, Usama M Ammar, Seyed-Omar Zaraei

Eur J Med Chem· December 2023

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Discovery of a non-covalent ligand for Rpn-13, a therapeutic target for hematological cancers.
Cody A Loy, Christine S Muli, Eslam M H Ali, Dan Xie, Mostafa H Ahmed

Bioorg Med Chem Lett· October 2023

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Changing incidence and survival of intrahepatic cholangiocarcinoma based on Surveillance, Epidemiology, and End Results Database (2000-2017).
Hassam Ali, Brandon Tedder, Syed Hamza Waqar, Rana Mohamed, Edward Lawson Cate, Eslam Ali

Ann Hepatobiliary Pancreat Surg· August 2022

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Identification of Novel Aryl Carboxamide Derivatives as Death-Associated Protein Kinase 1 (DAPK1) Inhibitors with Anti-Proliferative Activities: Design, Synthesis, In Vitro, and In Silico Biological Studies.
Ahmed Elkamhawy, Sora Paik, Eslam M H Ali, Ahmed H E Hassan, So Jin Kang

Pharmaceuticals (Basel)· August 2022

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Structural optimization of 4-(imidazol-5-yl)pyridine derivatives affords broad-spectrum anticancer agents with selective B-RAF/p38α kinase inhibitory activity: Synthesis, in vitro assays and in silico study.
Eslam M H Ali, Karim I Mersal, Usama M Ammar, Seyed-Omar Zaraei, Mohammed S Abdel-Maksoud

Eur J Pharm Sci· April 2022

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Inpatient outcomes of Dieulafoy's lesions in the United States.
Hassam Ali, Nicole Leigh Bolick, Rahul Pamarthy, Muhammad Fahd Farooq, Muhammad Hassan Farooq, Ali Eslam

Proc (Bayl Univ Med Cent)· March 2022

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New horizons in drug discovery of lymphocyte-specific protein tyrosine kinase (Lck) inhibitors: a decade review (2011-2021) focussing on structure-activity relationship (SAR) and docking insights.
Ahmed Elkamhawy, Eslam M H Ali, Kyeong Lee

J Enzyme Inhib Med Chem· December 2021

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Phentermine-Associated Pseudomembranous Colitis.
Narasimha Swamy Gollol Raju, Sriraksha Jayananda, Eslam Ali, Glenn Harvin

Am J Ther· September 2021

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Diagnostic Accuracy for Per-Patient Polyp Detection of Second-Generation Capsule Endoscopy Compared to Colonoscopy: A Meta-Analysis of Multicenter Studies.
Hassam Ali, Rahul Pamarthy, Shiza Sarfraz, Eslam Ali

Cureus· August 2021

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Facilitators and barriers to colorectal cancer screening in an outpatient setting.
Gbeminiyi Samuel, MaryKate Kratzer, Oghale Asagbra, Josef Kinderwater, Shiva Poola, Eslam Ali

World J Clin Cases· July 2021

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Discovery of New Imidazo[2,1-]thiazole Derivatives as Potent Pan-RAF Inhibitors with Promising and Anti-melanoma Activity.
Mohammed S Abdel-Maksoud, Mohammed I El-Gamal, Bong S Lee, Mahmoud M Gamal El-Din, Hong R Jeon, Eslam M H Ali

J Med Chem· May 2021

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Design, synthesis, biological evaluation, and docking studies of novel (imidazol-5-yl)pyrimidine-based derivatives as dual BRAF/p38α inhibitors.
Eslam M H Ali, Rania Farag A El-Telbany, Mohammed S Abdel-Maksoud, Usama M Ammar, Karim I Mersal

Eur J Med Chem· April 2021

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Design, synthesis and anti-inflammatory activity of imidazol-5-yl pyridine derivatives as p38α/MAPK14 inhibitor.
Eslam M H Ali, Mohammed S Abdel-Maksoud, Rasha Mohamed Hassan, Karim I Mersal, Usama M Ammar

Bioorg Med Chem· February 2021

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Design, synthesis, and biological evaluation of novel imidazole derivatives possessing terminal sulphonamides as potential BRAFinhibitors.
Eslam M H Ali, Mohammed S Abdel-Maksoud, Usama M Ammar, Karim I Mersal, Kyung Ho Yoo

Bioorg Chem· January 2021

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Ligand-based design, molecular dynamics and ADMET studies of suggested SARS-CoV-2 M inhibitors.
Nada M Mohamed, Eslam M H Ali, Asmaa M AboulMagd

RSC Adv· January 2021

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Modification of imidazothiazole derivatives gives promising activity in B-Raf kinase enzyme inhibition; synthesis, in vitro studies and molecular docking.
Usama M Ammar, Mohammed S Abdel-Maksoud, Karim I Mersal, Eslam M H Ali, Kyung Ho Yoo

Bioorg Med Chem Lett· October 2020

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Factors influencing inpatient colonoscopy bowel preparation quality.
Shiva Poola, Nannaya Jampala, Dmitry Tumin, Eslam Ali

Minerva Gastroenterol Dietol· September 2020

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Structural optimization of imidazothiazole derivatives affords a new promising series as B-Raf V600E inhibitors; synthesis, in vitro assay and in silico screening.
Usama M Ammar, Mohammed S Abdel-Maksoud, Eslam M H Ali, Karim I Mersal, Kyung Ho Yoo

Bioorg Chem· July 2020

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Design and synthesis of novel pyrrolo[2,3-b]pyridine derivatives targeting BRAF.
Mohammed S Abdel-Maksoud, Eslam M H Ali, Usama M Ammar, Karim I Mersal, Kyung Ho Yoo

Bioorg Med Chem· June 2020

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Endoscopic advances in the management of non-variceal upper gastrointestinal bleeding: A review.
Maliha Naseer, Karissa Lambert, Ahmed Hamed, Eslam Ali

World J Gastrointest Endosc· January 2020

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