Publications by authors named "Eugen Timin"

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Assay for evaluation of proarrhythmic effects of herbal products: Case study with 12 preparations.
Bozhidar Baltov, Stanislav Beyl, Igor Baburin, Jakob Reinhardt, Phillip Szkokan, Eugen Timin

Toxicol Rep· April 2023

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Key role of segment IS4 in Cav1.2 inactivation: link between activation and inactivation.
Stanislav Andranovits, Stanislav Beyl, Annette Hohaus, Eva Maria Zangerl-Plessl, Eugen Timin

Pflugers Arch· November 2017

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Upward movement of IS4 and IIIS4 is a rate-limiting stage in Ca1.2 activation.
Stanislav Beyl, Annette Hohaus, Stanislav Andranovits, Eugen Timin, Steffen Hering

Pflugers Arch· November 2016

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Direct Estimation of CaV1.2 Gating Parameters: Quantification of Voltage Sensor - Pore Transductions and their Modulation by FLP 64176.
Beyl Stanislav, Kügler Philipp, Timin Eugen, Hering Steffen

Curr Mol Pharmacol· August 2016

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Drug trapping in hERG K channels: (not) a matter of drug size?
Tobias Linder, Harald Bernsteiner, Priyanka Saxena, Florian Bauer, Thomas Erker, Eugen Timin

Medchemcomm· March 2016

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Structural insights into trapping and dissociation of small molecules in K⁺ channels.
Tobias Linder, Priyanka Saxena, Eugen Timin, Steffen Hering, Anna Stary-Weinzinger

J Chem Inf Model· November 2014

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Neutralisation of a single voltage sensor affects gating determinants in all four pore-forming S6 segments of Ca(V)1.2: a cooperative gating model.
Stanislav Beyl, Katrin Depil, Annette Hohaus, Anna Stary-Weinzinger, Tobias Linder, Eugen Timin

Pflugers Arch· October 2012

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Timothy mutation disrupts the link between activation and inactivation in Ca(V)1.2 protein.
Katrin Depil, Stanislav Beyl, Anna Stary-Weinzinger, Annette Hohaus, Eugen Timin

J Biol Chem· September 2011

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Pore stability and gating in voltage-activated calcium channels.
Steffen Hering, Stansilav Beyl, Anna Stary, Michaela Kudrnac, Annette Hohaus, Eugen Timin

Channels (Austin)· May 2011

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Physicochemical properties of pore residues predict activation gating of Ca V1.2: a correlation mutation analysis.
Stanislav Beyl, Katrin Depil, Annette Hohaus, Anna Stary-Weinzinger, Eugen Timin

Pflugers Arch· January 2011

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Molecular dynamics and mutational analysis of a channelopathy mutation in the IIS6 helix of Ca V 1.2.
Anna Stary, Michaela Kudrnac, Stanislav Beyl, Annette Hohaus, Eugen N Timin

Channels (Austin)· October 2010

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The hERG potassium channel and drug trapping: insight from docking studies with propafenone derivatives.
Khac-Minh Thai, Andreas Windisch, Daniela Stork, Anna Weinzinger, Andrea Schiesaro, Eugen N Timin

ChemMedChem· March 2010

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Different pathways for activation and deactivation in CaV1.2: a minimal gating model.
Stanislav Beyl, Philipp Kügler, Michaela Kudrnac, Annette Hohaus, Steffen Hering, Eugen Timin

J Gen Physiol· September 2009

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Coupled and independent contributions of residues in IS6 and IIS6 to activation gating of CaV1.2.
Michaela Kudrnac, Stanislav Beyl, Annette Hohaus, Anna Stary, Thomas Peterbauer, Eugen Timin

J Biol Chem· May 2009

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Probing the architecture of an L-type calcium channel with a charged phenylalkylamine: evidence for a widely open pore and drug trapping.
Stanislav Beyl, Eugen N Timin, Annette Hohaus, Anna Stary, Michaela Kudrnac

J Biol Chem· February 2007

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Structural determinants of L-type channel activation in segment IIS6 revealed by a retinal disorder.
Annette Hohaus, Stanislav Beyl, Michaela Kudrnac, Stanislav Berjukow, Eugen N Timin

J Biol Chem· November 2005

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