Publications by authors named "Eugene A Terefenko"

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Discovery of novel selective norepinephrine inhibitors: 1-(2-morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxides (WYE-114152).
David J O'Neill, Adedayo Adedoyin, Jenifer A Bray, Darlene C Deecher, Andrew Fensome, Eugene A Terefenko

J Med Chem· October 2011

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Structure-activity relationships of the 1-amino-3-(1H-indol-1-yl)-3-phenylpropan-2-ol series of monoamine reuptake inhibitors.
Paige E Mahaney, Callain Y Kim, Richard D Coghlan, Stephen T Cohn, Gavin D Heffernan, Eugene A Terefenko

Bioorg Med Chem Lett· October 2009

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1- or 3-(3-Amino-2-hydroxy-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones: potent, selective, and orally efficacious norepinephrine reuptake inhibitors.
Puwen Zhang, Eugene A Terefenko, Jenifer Bray, Darlene Deecher, Andrew Fensome

J Med Chem· September 2009

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3-(Arylamino)-3-phenylpropan-2-olamines as a new series of dual norepinephrine and serotonin reuptake inhibitors.
An T Vu, Stephen T Cohn, Eugene A Terefenko, William J Moore, Puwen Zhang

Bioorg Med Chem Lett· May 2009

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Synthesis and activity of novel 1- or 3-(3-amino-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones as selective norepinephrine reuptake inhibitors.
Puwen Zhang, Eugene A Terefenko, Casey C McComas, Paige E Mahaney, An Vu

Bioorg Med Chem Lett· December 2008

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1,5-Dihydro-benzo[e][1,4]oxazepin-2(1H)-ones containing a 7-(5'-cyanopyrrol-2-yl) group as nonsteroidal progesterone receptor modulators.
Jeffrey C Kern, Eugene A Terefenko, Andrew Fensome, Ray Unwalla, Jay Wrobel

Bioorg Med Chem Lett· September 2008

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7-aryl 1,5-dihydro-benzo[e][1,4]oxazepin-2-ones and analogs as non-steroidal progesterone receptor antagonists.
Puwen Zhang, Jeffrey C Kern, Eugene A Terefenko, Andrew Fensome, Ray Unwalla

Bioorg Med Chem· July 2008

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SAR studies of 6-(arylamino)-4,4-disubstituted-1-methyl-1,4-dihydro-benzo[d][1,3]oxazin-2-ones as progesterone receptor antagonists.
Jeffrey C Kern, Eugene A Terefenko, Andrew Fensome, Ray Unwallla, Jay Wrobel

Bioorg Med Chem Lett· January 2007

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SAR studies of 6-aryl-1,3-dihydrobenzimidazol-2-ones as progesterone receptor antagonists.
Eugene A Terefenko, Jeffrey Kern, Andrew Fensome, Jay Wrobel, Yuan Zhu

Bioorg Med Chem Lett· August 2005

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Synthesis and structure-activity relationship of novel 6-aryl-1,4-dihydrobenzo[d][1,3]oxazine-2-thiones as progesterone receptor modulators leading to the potent and selective nonsteroidal progesterone receptor agonist tanaproget.
Andrew Fensome, Reinhold Bender, Rajiv Chopra, Jeff Cohen, Mark A Collins, Eugene A Terefenko

J Med Chem· August 2005

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Novel 6-aryl-1,4-dihydrobenzo[d]oxazine-2-thiones as potent, selective, and orally active nonsteroidal progesterone receptor agonists.
Puwen Zhang, Eugene A Terefenko, Andrew Fensome, Jay Wrobel, Richard Winneker

Bioorg Med Chem Lett· April 2003

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6-Aryl-1,4-dihydro-benzo[d][1,3]oxazin- 2-ones: a novel class of potent, selective, and orally active nonsteroidal progesterone receptor antagonists.
Puwen Zhang, Eugene A Terefenko, Andrew Fensome, Jay Wrobel, Richard Winneker

J Med Chem· September 2002

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Potent nonsteroidal progesterone receptor agonists: synthesis and SAR study of 6-aryl benzoxazines.
Puwen Zhang, Eugene A Terefenko, Andrew Fensome, Zhiming Zhang, Yuan Zhu

Bioorg Med Chem Lett· March 2002

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