Publications by authors named "Eugene L Piatnitski Chekler"

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Structure-Based Design of Highly Selective Inhibitors of the CREB Binding Protein Bromodomain.
R Aldrin Denny, Andrew C Flick, Jotham Coe, Jonathan Langille, Arindrajit Basak, Eugene L Piatnitski Chekler

J Med Chem· July 2017

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Structure-Based Approach To Identify 5-[4-Hydroxyphenyl]pyrrole-2-carbonitrile Derivatives as Potent and Tissue Selective Androgen Receptor Modulators.
Ray Unwalla, James J Mousseau, Olugbeminiyi O Fadeyi, Chulho Choi, Kevin Parris, Eugene L Piatnitski Chekler

J Med Chem· July 2017

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Transcriptional Profiling of a Selective CREB Binding Protein Bromodomain Inhibitor Highlights Therapeutic Opportunities.
Eugene L Piatnitski Chekler, Jessica A Pellegrino, Thomas A Lanz, R Aldrin Denny, Andrew C Flick

Chem Biol· December 2015

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Perturbation of cellular proteostasis networks identifies pathways that modulate precursor and intermediate but not mature levels of frataxin.
Joseph F Nabhan, Renea L Gooch, Eugene L Piatnitski Chekler, Betsy Pierce, Christine E Bulawa

Sci Rep· December 2015

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1-(2-Hydroxy-2-methyl-3-phenoxypropanoyl)indoline-4-carbonitrile derivatives as potent and tissue selective androgen receptor modulators.
Eugene L Piatnitski Chekler, Rayomond Unwalla, Taukeer A Khan, Raghuram S Tangirala, Mark Johnson

J Med Chem· March 2014

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Target validation using chemical probes.
Mark E Bunnage, Eugene L Piatnitski Chekler, Lyn H Jones

Nat Chem Biol· April 2013

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Discovery of Dual VEGFR-2 and Tubulin Inhibitors with in Vivo Efficacy.
Eugene L Piatnitski Chekler, Alexander S Kiselyov, Xiaohu Ouyang, Xiaoling Chen, Vatee Pattaropong

ACS Med Chem Lett· December 2010

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Electrostatic docking of a supramolecular host-guest assembly to cytochrome c probed by bidirectional photoinduced electron transfer.
Katarzyna I Jankowska, Cynthia V Pagba, Eugene L Piatnitski Chekler, Kurt Deshayes, Piotr Piotrowiak

J Am Chem Soc· November 2010

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Discovery of a class of potent gap-junction modifiers as novel antiarrhythmic agents.
Eugene L Piatnitski Chekler, John A Butera, Li Di, Robert E Swillo, Gwen A Morgan

Bioorg Med Chem Lett· August 2009

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Arylphthalazines as potent, and orally bioavailable inhibitors of VEGFR-2.
Matthew A J Duncton, Eugene L Piatnitski Chekler, Reeti Katoch-Rouse, Dan Sherman, Wai C Wong

Bioorg Med Chem· January 2009

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Synthesis and evaluation of heteroaryl-ketone derivatives as a novel class of VEGFR-2 inhibitors.
Eugene L Piatnitski Chekler, Reeti Katoch-Rouse, Alexander S Kiselyov, Dan Sherman, Xiaohu Ouyang

Bioorg Med Chem Lett· August 2008

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