Publications by authors named "Eugene Mueller"

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Optimization of Data-Dependent Acquisition Parameters in Mass Spectrometry for Oligonucleotide Identification.
Audriy Jebet, Xipeng Ma, Liqing He, Adam J Anthony, Seongho Kim, Eugene Mueller

J Am Soc Mass Spectrom· November 2025

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Comparison of liver bile acid profiles in chronic alcohol feeding and NIAAA binge-on-chronic alcohol feeding mouse models.
Jing Feng, Liqing He, Xipeng Ma, Xinmin Yin, Eugene G Mueller

J Chromatogr B Analyt Technol Biomed Life Sci· August 2025

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Multiomics Studies on Metabolism Changes in Alcohol-Associated Liver Disease.
Liqing He, Raobo Xu, Xipeng Ma, Xinmin Yin, Eugene Mueller

J Proteome Res· November 2024

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Metabolomics analysis of urine from patients with alcohol-associated liver disease reveals dysregulated caffeine metabolism.
Raobo Xu, Liqing He, Vatsalya Vatsalya, Xipeng Ma, Seongho Kim, Eugene G Mueller

Am J Physiol Gastrointest Liver Physiol· February 2023

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Kinetic Isotope Effect Studies to Elucidate the Reaction Mechanism of RNA-Modifying Enzymes.
Govardhan R Veerareddygari, Eugene G Mueller

Methods Enzymol· May 2018

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Characterization of the catalytic disulfide bond in E. coli 4-thiouridine synthetase to elucidate its functional quaternary structure.
Govardhan Reddy Veerareddygari, Thomas C Klusman, Eugene G Mueller

Protein Sci· September 2016

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The Pseudouridine Synthases Proceed through a Glycal Intermediate.
Govardhan Reddy Veerareddygari, Sanjay K Singh, Eugene G Mueller

J Am Chem Soc· June 2016

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Metabolomic analysis of the effects of polychlorinated biphenyls in nonalcoholic fatty liver disease.
Xue Shi, Banrida Wahlang, Xiaoli Wei, Xinmin Yin, K Cameron Falkner, Eugene G Mueller

J Proteome Res· July 2012

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Unexpected linear ion trap collision-induced dissociation and Fourier transform ion cyclotron resonance infrared multi-photon dissociation fragmentation of a hydrated C-glycoside of 5-fluorouridine formed by the action of the pseudouridine synthases RluA and TruB.
Edward J Miracco, Bogdan Bogdanov, Eugene G Mueller

Rapid Commun Mass Spectrom· September 2011

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The products of 5-fluorouridine by the action of the pseudouridine synthase TruB disfavor one mechanism and suggest another.
Edward J Miracco, Eugene G Mueller

J Am Chem Soc· August 2011

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The handling of the mechanistic probe 5-fluorouridine by the pseudouridine synthase TruA and its consistency with the handling of the same probe by the pseudouridine synthases TruB and RluA.
Marguerite K McDonald, Edward J Miracco, Junjun Chen, Yizhou Xie, Eugene G Mueller

Biochemistry· January 2011

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Se-ing into selenocysteine biosynthesis.
Eugene G Mueller

Nat Chem Biol· September 2009

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Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure.
Charmaine Hoang, Junjun Chen, Caroline A Vizthum, Jason M Kandel, Christopher S Hamilton, Eugene G Mueller

Mol Cell· November 2006

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Mechanistic investigations of the pseudouridine synthase RluA using RNA containing 5-fluorouridine.
Christopher S Hamilton, Todd M Greco, Caroline A Vizthum, Joy M Ginter, Murray V Johnston, Eugene G Mueller

Biochemistry· October 2006

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Direct evidence for enzyme persulfide and disulfide intermediates during 4-thiouridine biosynthesis.
Chapman M Wright, Glenn D Christman, Ann M Snellinger, Murray V Johnston, Eugene G Mueller

Chem Commun (Camb)· August 2006

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Trafficking in persulfides: delivering sulfur in biosynthetic pathways.
Eugene G Mueller

Nat Chem Biol· April 2006

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Precursor complex structure of pseudouridine synthase TruB suggests coupling of active site perturbations to an RNA-sequestering peripheral protein domain.
Charmaine Hoang, Christopher S Hamilton, Eugene G Mueller, Adrian R Ferré-D'Amaré

Protein Sci· August 2005

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The roles of the essential Asp-48 and highly conserved His-43 elucidated by the pH dependence of the pseudouridine synthase TruB.
Christopher S Hamilton, Christopher J Spedaliere, Joy M Ginter, Murray V Johnston, Eugene G Mueller

Arch Biochem Biophys· January 2005

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The pseudouridine synthases: revisiting a mechanism that seemed settled.
Christopher J Spedaliere, Joy M Ginter, Murray V Johnston, Eugene G Mueller

J Am Chem Soc· October 2004

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Not all pseudouridine synthases are potently inhibited by RNA containing 5-fluorouridine.
Christopher J Spedaliere, Eugene G Mueller

RNA· February 2004

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A paradigm for biological sulfur transfers via persulfide groups: a persulfide-disulfide-thiol cycle in 4-thiouridine biosynthesis.
Chapman M Wright, Peter M Palenchar, Eugene G Mueller

Chem Commun (Camb)· November 2002

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Chips off the old block.
Eugene G Mueller

Nat Struct Biol· May 2002

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