Publications by authors named "Eva Hedlund"

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Transcriptional modulation unique to vulnerable motor neurons predicts ALS across species and SOD1 mutations.
Irene Mei, Susanne Nichterwitz, Melanie Leboeuf, Jik Nijssen, Isadora Lenoel, Eva Hedlund

Genome Res· September 2025

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Single-cell RNA-sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS.
Christoph Schweingruber, Jik Nijssen, Jonas Mechtersheimer, Stefan Reber, Mélanie Lebœuf, Eva Hedlund

Nat Commun· May 2025

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Intrinsic neuronal resilience as a tool for therapeutic discovery.
Stefania Corti, Eva Hedlund

Brain· April 2025

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Challenges of profiling motor neuron transcriptomes from human spinal cord.
Olivia Gautier, Jacob A Blum, James Maksymetz, Derek Chen, Christoph Schweingruber, Eva Hedlund

Neuron· December 2023

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Single-Cell mRNA-Seq of In Vitro-Derived Human Neurons Using Smart-Seq2.
Christoph Schweingruber, Jik Nijssen, Julio Aguila Benitez, Eva Hedlund

Methods Mol Biol· October 2022

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Mouse models of SMA show divergent patterns of neuronal vulnerability and resilience.
Victoria Woschitz, Irene Mei, Eva Hedlund, Lyndsay M Murray

Skelet Muscle· September 2022

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The Cell Autonomous and Non-Cell Autonomous Aspects of Neuronal Vulnerability and Resilience in Amyotrophic Lateral Sclerosis.
Christoph Schweingruber, Eva Hedlund

Biology (Basel)· August 2022

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Calf Muscle Oxygenation is Impaired and May Decline with Age in Young Patients with Total Cavopulmonary Connection.
Magne Sthen Bergdahl, Albert G Crenshaw, Eva Rylander Hedlund, Gunnar Sjöberg, Annika Rydberg

Pediatr Cardiol· February 2022

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Fontan circulation has improved life expectancy for infants born with complex heart disease over the last 50 years but has also resulted in significant morbidity.
Eva Hedlund, Bo Lundell

Acta Paediatr· January 2022

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Endurance training may improve exercise capacity, lung function and quality of life in Fontan patients.
Eva Hedlund, Bo Lundell

Acta Paediatr· January 2022

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Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity.
Jorge C Correia, Yildiz Kelahmetoglu, Paulo R Jannig, Christoph Schweingruber, Dasha Shvaikovskaya, Eva Hedlund

Cell Metab· November 2021

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Publisher Correction: Altered perivascular fibroblast activity precedes ALS disease onset.
Anna Månberg, Nathan Skene, Folkert Sanders, Marta Trusohamn, Julia Remnestål, Eva Hedlund

Nat Med· July 2021

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Spatial RNA Sequencing Identifies Robust Markers of Vulnerable and Resistant Human Midbrain Dopamine Neurons and Their Expression in Parkinson's Disease.
Julio Aguila, Shangli Cheng, Nigel Kee, Ming Cao, Menghan Wang, Eva Hedlund

Front Mol Neurosci· July 2021

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Altered perivascular fibroblast activity precedes ALS disease onset.
Anna Månberg, Nathan Skene, Folkert Sanders, Marta Trusohamn, Julia Remnestål, Eva Hedlund

Nat Med· April 2021

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Disrupted function of lactate transporter MCT1, but not MCT4, in Schwann cells affects the maintenance of motor end-plate innervation.
Filipa Bouçanova, Gill Pollmeier, Katalin Sandor, Carlos Morado Urbina, Jik Nijssen, Eva Hedlund

Glia· January 2021

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Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Daniel Jutzi, Sébastien Campagne, Ralf Schmidt, Stefan Reber, Jonas Mechtersheimer, Eva Hedlund

Nat Commun· December 2020

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LCM-seq reveals unique transcriptional adaptation mechanisms of resistant neurons and identifies protective pathways in spinal muscular atrophy.
Susanne Nichterwitz, Jik Nijssen, Helena Storvall, Christoph Schweingruber, Laura Helen Comley, Eva Hedlund

Genome Res· August 2020

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Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain.
Ahmed M Osman, Ying Sun, Terry C Burns, Liqun He, Nigel Kee, Eva Hedlund

Cell Rep· June 2020

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Appropriate heart rate during exercise in Fontan patients.
Eva R Hedlund, Liselott Söderström, Bo Lundell

Cardiol Young· May 2020

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Physical exercise may improve sleep quality in children and adolescents with Fontan circulation.
Eva R Hedlund, Li Villard, Bo Lundell, Gunnar Sjöberg

Cardiol Young· July 2019

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Axon-seq for in Depth Analysis of the RNA Content of Neuronal Processes.
Jik Nijssen, Julio Aguila, Eva Hedlund

Bio Protoc· July 2019

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Intact single muscle fibres from SOD1 amyotrophic lateral sclerosis mice display preserved specific force, fatigue resistance and training-like adaptations.
Arthur J Cheng, Ilary Allodi, Thomas Chaillou, Maja Schlittler, Niklas Ivarsson, Eva Hedlund

J Physiol· June 2019

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Modeling Motor Neuron Resilience in ALS Using Stem Cells.
Ilary Allodi, Jik Nijssen, Julio Aguila Benitez, Christoph Schweingruber, Andrea Fuchs, Eva Hedlund

Stem Cell Reports· June 2019

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A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate.
Phillip T Newton, Lei Li, Baoyi Zhou, Christoph Schweingruber, Maria Hovorakova, Eva Hedlund

Nature· March 2019

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