Publications by authors named "Eva Lion"

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Time-Series Transcriptome Analysis of the Older Adult Mouse Cochlea After Noise-Induced Hearing Loss Reveals an Acute Immune Response and Recovery-Associated Pathways.
Lize Sels, Fien Aben, Krystyna Szewczyk, Carole Faghel, Esther Bartholomeus, Eva Lion

Mol Neurobiol· November 2025

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AAV-mediated delivery of a proliferation inducing ligand (APRIL) to cortical neurons limits inflammation and demyelination in the corpus callosum of the cuprizone mouse model.
Leonardo Ricciardi, Federica Di Marco, Marion Decrop, Julia Di Stefano, Tejaswini Kakunuri, Eva Lion

J Neuroinflammation· October 2025

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Apolipoprotein E4 facilitates transfection of human monocyte-derived dendritic cells by lipid nanoparticles.
Izabella Lambart, Hannah Zaryouh, Jonas Van Audenaerde, Dana Liu, Delphine Quatannens, Eva Lion

Int J Pharm· June 2025

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Celluloepidemiology-A paradigm for quantifying infectious disease dynamics on a population level.
My K Ha, Anna Postovskaya, Maria Kuznetsova, Pieter Meysman, Vincent Van Deuren, Eva Lion

Sci Adv· May 2025

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Expanding the CAR toolbox with high throughput screening strategies for CAR domain exploration: a comprehensive review.
Gils Roex, Khloe S Gordon, Eva Lion, Michael E Birnbaum, Sébastien Anguille

J Immunother Cancer· April 2025

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Correction: WT1-mRNA dendritic cell vaccination of patients with glioblastoma multiforme, malignant pleural mesothelioma, metastatic breast cancer, and other solid tumors: type 1 T-lymphocyte responses are associated with clinical outcome.
Zwi N Berneman, Maxime De Laere, Paul Germonpré, Manon T Huizing, Yannick Willemen, Eva Lion

J Hematol Oncol· March 2025

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Analysis of Wilms' tumor protein 1 specific TCR repertoire in AML patients uncovers higher diversity in patients in remission than in relapsed.
Sofie Gielis, Donovan Flumens, Sanne van der Heijden, Maarten Versteven, Hans De Reu, Eva Lion

Ann Hematol· January 2025

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WT1-mRNA dendritic cell vaccination of patients with glioblastoma multiforme, malignant pleural mesothelioma, metastatic breast cancer, and other solid tumors: type 1 T-lymphocyte responses are associated with clinical outcome.
Zwi N Berneman, Maxime De Laere, Paul Germonpré, Manon T Huizing, Yannick Willemen, Eva Lion

J Hematol Oncol· January 2025

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A co-culture model to study modulators of tumor immune evasion through scalable arrayed CRISPR-interference screens.
Ramiro Martinez, Chiara Finocchiaro, Louis Delhaye, Fien Gysens, Jasper Anckaert, Eva Lion

Front Immunol· November 2024

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Integration of the PD-L1 inhibitor atezolizumab and WT1/DC vaccination into standard-of-care first-line treatment for patients with epithelioid malignant pleural mesothelioma-Protocol of the Immuno-MESODEC study.
Jolien Van den Bossche, Maxime De Laere, Koen Deschepper, Paul Germonpré, Yvan Valcke, Eva Lion

PLoS One· July 2024

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Training of epitope-TCR prediction models with healthy donor-derived cancer-specific T cells.
Donovan Flumens, Sofie Gielis, Esther Bartholomeus, Diana Campillo-Davo, Sanne van der Heijden, Eva Lion

Methods Cell Biol· April 2024

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Adjuvant Wilms' tumour 1-specific dendritic cell immunotherapy complementing conventional therapy for paediatric patients with high-grade glioma and diffuse intrinsic pontine glioma: protocol of a monocentric phase I/II clinical trial in Belgium.
Toon Van Genechten, Maxime De Laere, Jolien Van den Bossche, Barbara Stein, Kim De Rycke, Eva Lion

BMJ Open· March 2024

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IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts.
Astrid Van den Eynde, Laura Gehrcken, Tias Verhezen, Ho Wa Lau, Christophe Hermans, Eva Lion

J Hematol Oncol· February 2024

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Safety, tolerability, and immunogenicity of inactivated poliovirus vaccine with or without E.coli double mutant heat-labile toxin (dmLT) adjuvant in healthy adults; a phase 1 randomized study.
Rahsan Erdem, Ilse De Coster, Kanchanamala Withanage, Laina D Mercer, Arnaud Marchant, Eva Lion

Vaccine· March 2023

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One-step CRISPR-Cas9-mediated knockout of native TCRαβ genes in human T cells using RNA electroporation.
Donovan Flumens, Diana Campillo-Davo, Ibo Janssens, Gils Roex, Jorrit De Waele, Eva Lion

STAR Protoc· March 2023

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In vitro expansion of Wilms' tumor protein 1 epitope-specific primary T cells from healthy human peripheral blood mononuclear cells.
Sanne van der Heijden, Donovan Flumens, Maarten Versteven, Stefanie Peeters, Hans De Reu, Eva Lion

STAR Protoc· March 2023

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Humoral and Cellular Immune Responses against SARS-CoV-2 after Third Dose BNT162b2 following Double-Dose Vaccination with BNT162b2 versus ChAdOx1 in Patients with Cancer.
Yana Debie, Jonas R M Van Audenaerde, Timon Vandamme, Lieselot Croes, Laure-Anne Teuwen, Eva Lion

Clin Cancer Res· February 2023

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Anti-Tumor Potency of Short-Term Interleukin-15 Dendritic Cells Is Potentiated by Silencing of Programmed-Death Ligands.
Maarten Versteven, Donovan Flumens, Diana Campillo-Davó, Hans De Reu, Laura Van Bruggen, Eva Lion

Front Immunol· May 2022

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Two for one: targeting BCMA and CD19 in B-cell malignancies with off-the-shelf dual-CAR NK-92 cells.
Gils Roex, Diana Campillo-Davo, Donovan Flumens, Philip Anthony Gilbert Shaw, Laurens Krekelbergh, Eva Lion

J Transl Med· March 2022

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Preexisting memory CD4 T cells in naïve individuals confer robust immunity upon hepatitis B vaccination.
George Elias, Pieter Meysman, Esther Bartholomeus, Nicolas De Neuter, Nina Keersmaekers, Eva Lion

Elife· January 2022

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Novel Insights on MRGPRX2-Mediated Hypersensitivity to Neuromuscular Blocking Agents And Fluoroquinolones.
Jessy Elst, Marcus Maurer, Vito Sabato, Margaretha A Faber, Chris H Bridts, Eva Lion

Front Immunol· October 2021

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Trial Watch: Adoptive TCR-Engineered T-Cell Immunotherapy for Acute Myeloid Leukemia.
Diana Campillo-Davo, Sébastien Anguille, Eva Lion

Cancers (Basel)· September 2021

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The Ins and Outs of Messenger RNA Electroporation for Physical Gene Delivery in Immune Cell-Based Therapy.
Diana Campillo-Davo, Maxime De Laere, Gils Roex, Maarten Versteven, Donovan Flumens, Eva Lion

Pharmaceutics· March 2021

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Safety and clinical efficacy of BCMA CAR-T-cell therapy in multiple myeloma.
Gils Roex, Marijke Timmers, Kristien Wouters, Diana Campillo-Davo, Donovan Flumens, Eva Lion

J Hematol Oncol· December 2020

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The Quest for the Best: How TCR Affinity, Avidity, and Functional Avidity Affect TCR-Engineered T-Cell Antitumor Responses.
Diana Campillo-Davo, Donovan Flumens, Eva Lion

Cells· July 2020

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