Publications by authors named "Evan D Kharasch"

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Population Pharmacokinetics of Intravenous Methadone Enantiomers in Adults: A Comprehensive Model.
Thomas K Henthorn, Evan D Kharasch

Clin Pharmacol Ther· December 2025

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Combined Pecto-intercostal Fascial Plane and Rectus Sheath Blocks Versus Local Infiltration for Pain Management Following Pediatric Cardiac Surgery: A Randomized Clinical Trial.
Lisa M Einhorn, Evan D Kharasch, Janice Lim, Matthew Fuller, Jennifer L Turi

Anesth Analg· October 2025

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Urine C-reactive protein content and non-invasive molecular grading of renal cell carcinoma.
Jeremiah J Morrissey, Marilee A Fisher, Evan D Kharasch

Kidney Cancer J· October 2025

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The Nine Lives of Ketamine: From CI-581 to Present Day Clinical Application-Commentary on Domino et al.
Evan D Kharasch

Clin Pharmacol Ther· June 2025

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Etomidate and its derivatives: time to say goodbye? Response to Br J Anaesth 2024; 134: 11-13.
Andrew Bowdle, Evan D Kharasch

Br J Anaesth· May 2025

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Evaluating respiratory depression after methadone administration in surgical patients: protocol for a systematic review and meta-analysis.
Eduardo Nunez-Rodriguez, Guido Mazzinari, Sarah Lumsden, Kate J Krause, Nicolas Cortes, Evan D Kharasch

BMJ Open· May 2025

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What's old is new again: opioid and benzodiazepine actions on ventilation, a reminder of the importance of knowing one's drugs.
Konrad Meissner, Evan D Kharasch

Br J Anaesth· April 2025

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Opioid use in treated and untreated obstructive sleep apnoea: remifentanil pharmacokinetics and pharmacodynamics in adult volunteers.
Anil R Maharaj, Michael C Montana, Christoph P Hornik, Evan D Kharasch

Br J Anaesth· March 2025

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Morphine and hydromorphone pharmacokinetics in human volunteers: population-based modelling of interindividual and opioid-related variability.
Konrad Meissner, Erik Olofsen, Albert Dahan, Evan D Kharasch

Br J Anaesth· February 2025

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Epidural methadone and morphine pharmacokinetics and clinical effects in healthy volunteers: A randomized, crossover-design trial.
Alexander Hincker, Matthew Reschke, Yehuda Ginosar, Leonid Kagan, Evan D Kharasch

Br J Clin Pharmacol· November 2024

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Intraoperative methadone administration for total mastectomy: A single center retrospective study.
Juan P Cata, Yusuf Zaidi, Juan Jose Guerra-Londono, Evan D Kharasch, Matthew Piotrowski

J Clin Anesth· November 2024

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Methadone metabolism and cytochrome P450 polymorphisms: a systematic review and meta-analysis.
Seenae Eum, Nicholas P Vernacchia, Nia Doughty, Sahar Mehrzad, Andrew H Talal, Evan D Kharasch

Expert Opin Drug Metab Toxicol· November 2024

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Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2B6 Genotype and Methadone Therapy.
Katherine M Robinson, Seenae Eum, Zeruesenay Desta, Rachel F Tyndale, Andrea Gaedigk, Evan D Kharasch

Clin Pharmacol Ther· October 2024

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In Response.
Sarah Lumsden, Evan D Kharasch, Juan Cata

Anesth Analg· October 2024

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Methadone and Enhanced Recovery After Surgery: Concepts and Protocols.
Vijay K Ramaiah, Evan D Kharasch

Anesth Analg· September 2024

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Single-dose Intraoperative Methadone for Pain Management in Pediatric Tonsillectomy: A Randomized Double-blind Clinical Trial.
Lisa M Einhorn, Julia Hoang, Jong Ok La, Evan D Kharasch

Anesthesiology· September 2024

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Intraoperative Methadone and Postoperative Anesthesia Care Unit Outcomes: A Retrospective Cohort Analysis.
Evan D Kharasch

Anesthesiology· August 2024

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Intrasubject Variability in Intravenous and Oral Probes for Hepatic and First-Pass CYP3A Activity.
Evan D Kharasch, Christine Hoffer, Pamela Bedynek

Clin Pharmacokinet· August 2024

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Intraoperative Methadone Administration Is Not Associated With an Increase in Perioperative Use of Naloxone: A Retrospective Study.
Sarah Lumsden, Evan D Kharasch, Bryce Speer, Andrzej Kwater, Tong Joo Gan

Anesth Analg· May 2024

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Coronavirus Disease-2019 Pandemic Effects on Patient Decisions Regarding Clinical Trial Participation.
Evan D Kharasch, Carrie Schlabaugh, Emmalee Metzler, Alicja Schultz

Anesth Analg· April 2024

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Pharmacogenetic Influence on Stereoselective Steady-State Disposition of Bupropion.
Evan D Kharasch, Eric J Lenze

Drug Metab Dispos· April 2024

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Natural Products Inhibition of Cytochrome P450 2B6 Activity and Methadone Metabolism.
Pan-Fen Wang, Yanming Yang, Vishal Patel, Alicia Neiner, Evan D Kharasch

Drug Metab Dispos· February 2024

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Scholarly Debate About Drug Efficacy in Scientific Journals Is "Protected Speech," Not Libel.
Evan D Kharasch, Paul B Klaas, William L Lanier

Mayo Clin Proc· February 2024

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Opioid sensitivity in treated and untreated obstructive sleep apnoea: a prospective cohort study.
Michael C Montana, Michael McLeland, Marilee Fisher, Lindsay Juriga, Patrick M Ercole, Evan D Kharasch

Br J Anaesth· January 2024

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