Publications by authors named "Ewen D D Calder"

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Indolequinone-Based Hypoxia-Activated Proteolysis Targeting Chimeras Selectively Degrade BRD4 in Hypoxic Cancer Cells.
Marta Serafini, Sophie A Twigger, George Delfas, Maxim Mallerman, Elliot P Bailey, Ewen D D Calder

J Am Chem Soc· October 2025

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Discovering covalent cyclic peptide inhibitors of peptidyl arginine deiminase 4 (PADI4) using mRNA-display with a genetically encoded electrophilic warhead.
Isabel R Mathiesen, Ewen D D Calder, Simone Kunzelmann, Louise J Walport

Commun Chem· December 2024

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Corrigendum: HPLC for at-line reaction monitoring and purification improves yield and purity of tRNA.
Polona Megušar, Ewen D D Calder, Tina Vodopivec Seravalli, Sergeja Lebar, Louise J Walport

Front Mol Biosci· October 2024

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HPLC for at-line reaction monitoring and purification improves yield and purity of tRNA.
Polona Megušar, Ewen D D Calder, Tina Vodopivec Seravalli, Sergeja Lebar, Louise J Walport

Front Mol Biosci· September 2024

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Zap-Pano: a Photocaged Prodrug of the KDAC Inhibitor Panobinostat.
Kathrin S Troelsen, Ewen D D Calder, Anna Skwarska, Deborah Sneddon, Ester M Hammond

ChemMedChem· December 2021

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Fluorescent Amino Acid Initiated de novo Cyclic Peptides for the Label-Free Assessment of Cell Permeability*.
Yuteng Wu, M Teresa Bertran, James Rowley, Ewen D D Calder, Dhira Joshi

ChemMedChem· October 2021

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Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor.
Anna Skwarska, Ewen D D Calder, Deborah Sneddon, Hannah Bolland, Maria L Odyniec

Cell Chem Biol· September 2021

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Strategies to expand peptide functionality through hybridisation with a small molecule component.
Yuteng Wu, Jack Williams, Ewen D D Calder, Louise J Walport

RSC Chem Biol· February 2021

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One-Pot Asymmetric Synthesis of Alkylidene 1-Alkylindan-1-ols Using Brønsted Acid and Palladium Catalysis.
Réka J Faggyas, Ewen D D Calder, Claire Wilson, Andrew Sutherland

J Org Chem· November 2017

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Clinical Advances of Hypoxia-Activated Prodrugs in Combination With Radiation Therapy.
Ishna N Mistry, Matthew Thomas, Ewen D D Calder, Stuart J Conway, Ester M Hammond

Int J Radiat Oncol Biol Phys· August 2017

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Characterization of HSP90 isoforms in transformed bovine leukocytes infected with Theileria annulata.
Jane H Kinnaird, Meetali Singh, Victoria Gillan, William Weir, Ewen D D Calder

Cell Microbiol· March 2017

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Intermolecular Aryl C-H Amination through Sequential Iron and Copper Catalysis.
Mohamed A B Mostafa, Ewen D D Calder, Daugirdas T Racys, Andrew Sutherland

Chemistry· January 2017

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Synthesis of Allylic Amide Functionalized 2H-Chromenes and Coumarins Using a One-Pot Overman Rearrangement and Gold(I)-Catalyzed Hydroarylation.
Salaheddin A I Sharif, Ewen D D Calder, Alexander H Harkiss, Marie Maduro, Andrew Sutherland

J Org Chem· October 2016

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Synthesis of 5-Amino-2,5-dihydro-1H-benzo[b]azepines Using a One-Pot Multibond Forming Process.
Salaheddin A I Sharif, Ewen D D Calder, Fábio G Delolo, Andrew Sutherland

J Org Chem· August 2016

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One-Pot Synthesis of 5-Amino-2,5-dihydro-1-benzoxepines: Access to Pharmacologically Active Heterocyclic Scaffolds.
Ewen D D Calder, Salaheddin A I Sharif, Fiona I McGonagle, Andrew Sutherland

J Org Chem· May 2015

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Enantioselective Synthesis of 3-Methyleneindan-1-ols via a One-Pot Allylboration-Heck Reaction of 2-Bromobenzaldehydes.
Ewen D D Calder, Andrew Sutherland

Org Lett· May 2015

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Preparation of amino-substituted indenes and 1,4-dihydronaphthalenes using a one-pot multireaction approach: total synthesis of oxybenzo[c]phenanthridine alkaloids.
Ewen D D Calder, Fiona I McGonagle, Alexander H Harkiss, Grant A McGonagle, Andrew Sutherland

J Org Chem· August 2014

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Stereodivergent organocatalytic intramolecular Michael addition/lactonization for the asymmetric synthesis of substituted dihydrobenzofurans and tetrahydrofurans.
Dorine Belmessieri, Alix de la Houpliere, Ewen D D Calder, James E Taylor, Andrew D Smith

Chemistry· July 2014

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Preparation of anti-vicinal amino alcohols: asymmetric synthesis of D-erythro-sphinganine, (+)-spisulosine, and D-ribo-phytosphingosine.
Ewen D D Calder, Ahmed M Zaed, Andrew Sutherland

J Org Chem· July 2013

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