Publications by authors named "Fabian Model"

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Five-year efficacy outcomes of ocrelizumab in relapsing multiple sclerosis: A propensity-matched comparison of the OPERA studies with other disease-modifying therapies in real-world lines of treatments.
Erwan Muros-Le Rouzic, Yanic Heer, Sean Yiu, Viola Tozzi, Stefan Braune, Fabian Model

J Cent Nerv Syst Dis· September 2024

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Estimating drug concentration-response relationships by applying causal inference methods for continuous point exposures and time-to-event outcomes.
Sean Yiu, Qing Wang, Francois Mercier, Marianna Manfrini, Harold Koendgen, Fabian Model

Stat Methods Med Res· December 2023

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Blood neurofilament light levels predict non-relapsing progression following anti-CD20 therapy in relapsing and primary progressive multiple sclerosis: findings from the ocrelizumab randomised, double-blind phase 3 clinical trials.
Amit Bar-Or, Gian-Andrea Thanei, Christopher Harp, Corrado Bernasconi, Ulrike Bonati, Fabian Model

EBioMedicine· July 2023

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Association of Higher Ocrelizumab Exposure With Reduced Disability Progression in Multiple Sclerosis.
Stephen L Hauser, Amit Bar-Or, Martin S Weber, Heidemarie Kletzl, Andreas Günther, Fabian Model

Neurol Neuroimmunol Neuroinflamm· March 2023

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Recurrent disability progression endpoints in multiple sclerosis clinical trials.
Alexandra Bühler, Marcel Wolbers, Fabian Model, Qing Wang, Shibeshih Belachew

Mult Scler· January 2023

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Risk of requiring a wheelchair in primary progressive multiple sclerosis: Data from the ORATORIO trial and the MSBase registry.
Helmut Butzkueven, Tim Spelman, Dana Horakova, Stella Hughes, Claudio Solaro, Fabian Model

Eur J Neurol· April 2022

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Ocrelizumab in relapsing and primary progressive multiple sclerosis: Pharmacokinetic and pharmacodynamic analyses of OPERA I, OPERA II and ORATORIO.
Ekaterina Gibiansky, Claire Petry, Francois Mercier, Andreas Günther, Ann Herman, Fabian Model

Br J Clin Pharmacol· June 2021

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Contribution of Relapse-Independent Progression vs Relapse-Associated Worsening to Overall Confirmed Disability Accumulation in Typical Relapsing Multiple Sclerosis in a Pooled Analysis of 2 Randomized Clinical Trials.
Ludwig Kappos, Jerry S Wolinsky, Gavin Giovannoni, Douglas L Arnold, Qing Wang, Fabian Model

JAMA Neurol· September 2020

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Five years of ocrelizumab in relapsing multiple sclerosis: OPERA studies open-label extension.
Stephen L Hauser, Ludwig Kappos, Douglas L Arnold, Amit Bar-Or, Bruno Brochet, Fabian Model

Neurology· September 2020

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Initiation of symptomatic medication in Alzheimer's disease clinical trials: Hypothetical versus treatment policy approach.
Michael C Donohue, Fabian Model, Paul Delmar, Nicola Volye, Hong Liu-Seifert

Alzheimers Dement· May 2020

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Chronic white matter lesion activity predicts clinical progression in primary progressive multiple sclerosis.
Colm Elliott, Shibeshih Belachew, Jerry S Wolinsky, Stephen L Hauser, Ludwig Kappos, Fabian Model

Brain· September 2019

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DNA methylation biomarkers of prostate cancer: confirmation of candidates and evidence urine is the most sensitive body fluid for non-invasive detection.
Shannon R Payne, Jurgen Serth, Martin Schostak, Jorn Kamradt, Arne Strauss, Fabian Model

Prostate· September 2009

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Circulating methylated SEPT9 DNA in plasma is a biomarker for colorectal cancer.
Theo deVos, Reimo Tetzner, Fabian Model, Gunter Weiss, Matthias Schuster

Clin Chem· July 2009

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Sensitive detection of colorectal cancer in peripheral blood by septin 9 DNA methylation assay.
Robert Grützmann, Bela Molnar, Christian Pilarsky, Jens K Habermann, Peter M Schlag, Fabian Model

PLoS One· February 2009

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Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue.
Georg Wieczorek, Anne Asemissen, Fabian Model, Ivana Turbachova, Stefan Floess

Cancer Res· January 2009

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DNA methylation biomarkers for blood-based colorectal cancer screening.
Catherine Lofton-Day, Fabian Model, Theo Devos, Reimo Tetzner, Juergen Distler

Clin Chem· February 2008

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DNA methylation analysis as novel tool for quality control in regenerative medicine.
Stephen Rapko, Udo Baron, Ulrich Hoffmüller, Fabian Model, Leslie Wolfe

Tissue Eng· September 2007

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Identification and validation of colorectal neoplasia-specific methylation markers for accurate classification of disease.
Fabian Model, Neal Osborn, David Ahlquist, Robert Gruetzmann, Bela Molnar

Mol Cancer Res· February 2007

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Aristaless-like homeobox-4 gene methylation is a potential marker for colorectal adenocarcinomas.
Matthias P A Ebert, Fabian Model, Suzanne Mooney, Kari Hale, Joe Lograsso

Gastroenterology· November 2006

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Association of DNA methylation of phosphoserine aminotransferase with response to endocrine therapy in patients with recurrent breast cancer.
John W M Martens, Inko Nimmrich, Thomas Koenig, Maxime P Look, Nadia Harbeck, Fabian Model

Cancer Res· May 2005

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Statistical process control for large scale microarray experiments.
Fabian Model, Thomas König, Christian Piepenbrock, Péter Adorján

Bioinformatics· October 2004

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Differences in DNA methylation patterns between humans and chimpanzees.
Wolfgang Enard, Anne Fassbender, Fabian Model, Péter Adorján, Svante Pääbo

Curr Biol· February 2004

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Tumour class prediction and discovery by microarray-based DNA methylation analysis.
Péter Adorján, Jürgen Distler, Evelyne Lipscher, Fabian Model, Jürgen Müller

Nucleic Acids Res· March 2002

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